Bottromycin A2
- BTM A2 - I 337B
Axon N0013
CAS:
15005-62-6
- Optical Purity: Optically pure
- Soluble in water
- MF: C42H62N8O7S
- MW: 823.06
Description
Antibacterial (gram-positive), potent antibiotic against MRSA and VRE, inhibits bacterial protein synthesis.
Source information: Streptomyces, No. 3668-L2
More Information
| Parent CAS No. | 15005-62-6 |
|---|---|
| Chemical Name | (R)-methyl 3-((2S,3S)-2-((S)-2-((Z)-((3S,6S,14R,14aS)-6-tert-butyl-3-isopropyl-14-methyl-1,4,10-trioxododecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecin-7(8H)-ylidene)amino)-3,3-dimethylbutanamido)-3-phenylbutanamido)-3-(thiazol-2-yl)propanoate |
| SMILES | C1(=O)[C@H](C(C)C)NC(=O)[C@]2([H])[C@@](C)([H])CCN2C(=O)CN/C(=N[C@@H](C(C)(C)C)C(=O)N[C@@]([H])([C@@H](C)C2C=CC=CC=2)C(=O)N[C@H](CC(OC)=O)C2SC=CN=2)/[C@H](C(C)(C)C)N1 |&1:2,9,11,23,31,33,44,55,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | Antibacterial and antibiotic |
References
- S Nakamura et al. Isolation and characterization of bottromycins A2, B2, C2. J Antibiot (Tokyo). 1967 Jan;20(1):1-5.
- H Gouda et al. Three-dimensional solution structure of bottromycin A2: a potent antibiotic active against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci. Chem Pharm Bull (Tokyo). 2012;60(2):169-71. doi: 10.1248/cpb.60.169.
