Althiomycin
- Matamycin - NSC 102809
Axon N0002
CAS:
12656-40-5
- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C16H17N5O6S2
- MW: 439.47
Description
Bacterial protein synthesis inhibitor, antibacterial (gram-positive & negative).
Source information: Streptomyces althioticus No. 245-Z2
More Information
| Parent CAS No. | 12656-40-5 |
|---|---|
| Chemical Name | (S,E)-N-(2-hydroxy-1-(4-(4-methoxy-2-oxo-2,5-dihydro-1H-pyrrole-1-carbonyl)-4,5-dihydrothiazol-2-yl)ethyl)-2-((hydroxyimino)methyl)thiazole-4-carboxamide |
| SMILES | C(NC(=O)C1=CSC(/C=N/O)=N1)(CO)C1=N[C@@H](C(=O)N2C(=O)C=C(OC)C2)CS1 |w:0,&1:16,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | Antibacterial |
References
- H Yamaguchi et al. A new antibiotic, althiomycin. J Antibiot (Tokyo). 1957 Sep;10(5):195-200.
- H Sakakibara et al. The structure of althiomycin. J Antibiot (Tokyo). 1974 Nov;27(11):897-9.
- HA Kirst et al. Structure of althiomycin. J Antibiot (Tokyo). 1975 Apr;28(4):286-91.
- H Fujimoto et al. J Antibiot (Tokyo). 1970 Jun;23(6):271-5.
- P Zarantonello et al. Total synthesis and semi-synthetic approaches to analogues of antibacterial natural product althiomycin. Bioorg Med Chem Lett. 2002 Feb 25;12(4):561-5.
