OICR-12694
- JNJ-65234637
Axon 4269
CAS:
2360625-97-2
- Optical Purity: 98% e.e.
- Soluble in DMSO
- MF: C29H28ClF3N8O4
- MW: 645.03
Description
OICR-12694 is a highly potent, selective, and orally bioavailable inhibitor of B cell lymphoma 6 (BCL6) with low nanomolar DLBCL cell growth inhibition and an excellent oral pharmacokinetic profile.
More Information
| Parent CAS No. | 2360625-97-2 |
|---|---|
| Chemical Name | (S)-5-(1-(2-(3-Chloro-6-(2,4-dimethylpiperazin-1-yl)-2-fluoropyridin-4-ylamino)-2-oxoethyl)-4-oxo-4,6,7,8-tetrahydro-1H-dipyrrolo[1,2-a:2',3'-d]pyrimidin-3-yl)-3,4-difluoro-2-hydroxybenzamide |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C12C(C3C(F)=C(F)C(O)=C(C(N)=O)C=3)=CN(CC(=O)NC3C(Cl)=C(F)N=C(N4CCN(C)C[C@@H]4C)C=3)C=1N=C1CCCN1C2=O |&1:33,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | BCL6 inhibitor |
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