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OICR-12694

 - JNJ-65234637
Axon 4269
CAS:  2360625-97-2
  • Optical Purity:  98% e.e.
  • Soluble in DMSO
  • MF:  C29H28ClF3N8O4
  • MW:  645.03

Description

OICR-12694 is a highly potent, selective, and orally bioavailable inhibitor of B cell lymphoma 6 (BCL6) with low nanomolar DLBCL cell growth inhibition and an excellent oral pharmacokinetic profile.

More Information

Parent CAS No. 2360625-97-2
Chemical Name (S)-5-(1-(2-(3-Chloro-6-(2,4-dimethylpiperazin-1-yl)-2-fluoropyridin-4-ylamino)-2-oxoethyl)-4-oxo-4,6,7,8-tetrahydro-1H-dipyrrolo[1,2-a:2',3'-d]pyrimidin-3-yl)-3,4-difluoro-2-hydroxybenzamide
extra_info Sold in collaboration with Chemietek
SMILES C12C(C3C(F)=C(F)C(O)=C(C(N)=O)C=3)=CN(CC(=O)NC3C(Cl)=C(F)N=C(N4CCN(C)C[C@@H]4C)C=3)C=1N=C1CCCN1C2=O |&1:33,r|
MFCD N.A.
InChi N.A.
InChiKey N.A.
CID N.A.
Short Description BCL6 inhibitor

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