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MK 0354
Axon 1576
CAS:
851776-28-8
Purity:
99%
- Soluble in DMSO
- MF: C7H8N6
- MW: 176.18
Description
Partial agonist of Niacin receptor, G-protein coupled receptor 109a
More Information
| Parent CAS No. | 851776-28-8 |
|---|---|
| Chemical Name | 3-(1H-Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole |
| SMILES | C1CC2NN=C(C3=NN=NN3)C=2C1 |
| MFCD | MFCD12400897 |
| InChi | InChI=1S/C7H8N6/c1-2-4-5(3-1)8-9-6(4)7-10-12-13-11-7/h1-3H2,(H,8,9)(H,10,11,12,13) |
| InChiKey | LTQYSJKGRPGMPO-UHFFFAOYSA-N |
| CID | 11159621 |
| Short Description | Niacin receptor partial agonist |
References
- E Lai et al, Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans. J. Clin. Lipidol. 2008, 2(5), 375-383.
- G Semple et al. 3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice. JMC. 2008, 51(16), 5101.
