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SA-15-P
Axon 3980
CAS:
852846-00-5
Purity:
99%
- Soluble in DMSO and EtOH
- MF: C26H24N2O4
- MW: 428.48
Description
SA-15-P is a first-in-class inhibitor of lymphocyte activation gene 3 (LAG-3) with IC50 values of 4.21 and 6.52 μM for LAG-3/MHCII and LAG-3/FGL1 interactions, respectively.
More Information
| Parent CAS No. | 852846-00-5 |
|---|---|
| Chemical Name | N-(4-(2-(1-Benzyl-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxoethoxy)phenyl)furan-2-carboxamide |
| SMILES | C1(OCC(=O)C2=C(C)N(CC3C=CC=CC=3)C(C)=C2)C=CC(NC(=O)C2=CC=CO2)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C26H24N2O4/c1-18-15-23(19(2)28(18)16-20-7-4-3-5-8-20)24(29)17-32-22-12-10-21(11-13-22)27-26(30)25-9-6-14-31-25/h3-15H,16-17H2,1-2H3,(H,27,30) |
| InChiKey | IYGLJCOGIQDUAE-UHFFFAOYSA-N |
| CID | 4786555 |
| Short Description | LAG-3 inhibitor |
