List of publications using AS 1517499 (Axon 1992) purchased from Axon Medchem

(Total 91 citations listed from 2014; updated up to June 2022) 

2022
Fang, F., Cao, W., Mu, Y., Okuyama, H., Li, L., Qiu, J., ... & Goronzy, J. J. (2022). IL-4 prevents adenosine-mediated immunoregulation by inhibiting CD39 expression. JCI Insight, 7(12).
https://insight.jci.org/articles/view/157509

Lee, Y. J., Kim, K., Kim, M., Ahn, Y. H., & Kang, J. L. (2022). Inhibition of STAT6 Activation by AS1517499 Inhibits Expression and Activity of PPARγ in Macrophages to Resolve Acute Inflammation in Mice. Biomolecules, 12(3), 447.
https://www.mdpi.com/2218-273X/12/3/447/htm
https://www.mdpi.com/2218-273X/12/3/447

Hara, T., Kasagi, Y., Wang, J., Sasaki, M., Aaron, B., Karami, A., ... & Muir, A. B. (2022). CD73+ Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis. Cellular and Molecular Gastroenterology and Hepatology, 13(5), 1449-1467.
https://www.sciencedirect.com/science/article/pii/S2352345X22000182

2021
Kimura, S., Noguchi, H., Nanbu, U., & Nakayama, T. (2021). Macrophage CCL22 expression promotes lymphangiogenesis in patients with tongue squamous cell carcinoma via IL-4/STAT6 in the tumor microenvironment. Oncology Letters, 21(5), 1-11.
https://www.spandidos-publications.com/10.3892/ol.2021.12644

Li, P., Li, X., Deng, P., Wang, D., Bai, X., Li, Y., ... & Yi, B. (2021). Activation of adenosine A3 receptor reduces early brain injury by alleviating neuroinflammation after subarachnoid hemorrhage in elderly rats. Aging (Albany Ny), 13(1), 694.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835045/

Dumigan, A., Cappa, O., Morris, B., Calderon-Gonzalez, R., Mills, G., Lancaster, R., ... & Bengoechea, J. A. (2021). In vivo single cell transcriptomics reveals Klebsiella pneumoniae rewiring of lung macrophages to promote infection. bioRxiv.
https://www.biorxiv.org/content/10.1101/2021.10.18.464784v1.full

Li, S., olde Heuvel, F., Rehman, R., Li, Z., Aousji, O., Froehlich, A., ... & Roselli, F. (2021). Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection. bioRxiv.
https://www.biorxiv.org/content/10.1101/2021.12.01.470746v1.full

Wu, W. J., Wang, S. H., Wu, C. C., Su, Y. A., Chiang, C. Y., Lai, C. H., ... & Lee, Y. J. (2021). IL-4 and IL-13 Promote Proliferation of Mammary Epithelial Cells through STAT6 and IRS-1. International journal of molecular sciences, 22(21), 12008.
https://www.mdpi.com/1422-0067/22/21/12008/htm

Jiao, B., An, C., Tran, M., Du, H., Wang, P., Zhou, D., & Wang, Y. (2021). Pharmacological Inhibition of STAT6 Ameliorates Myeloid Fibroblast Activation and Alternative Macrophage Polarization in Renal Fibrosis. Frontiers in Immunology, 12. 735014.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426438/

Deimel, L. P., Li, Z., Roy, S., & Ranasinghe, C. (2021). STAT3 determines IL-4 signalling outcomes in naïve T cells. Scientific reports, 11(1), 1-14.
https://www.nature.com/articles/s41598-021-89860-7
* both Stattic and AS1517499 from Axon Medchem

Chu, K. H., Lin, S. Y., & Chiang, B. L. (2021). STAT6 Pathway Is Critical for the Induction and Function of Regulatory T Cells Induced by Mucosal B Cells. Frontiers in immunology, 3651.
https://www.frontiersin.org/articles/10.3389/fimmu.2020.615868/full

2020
Portales-Cervantes, L., Crump, O. M., Dada, S., Liwski, C. R., Gotovina, J., Haidl, I. D., & Marshall, J. S. (2020). IL-4 enhances interferon production by virus-infected human mast cells. Journal of Allergy and Clinical Immunology, 146(3), 675-677.
https://www.jacionline.org/article/S0091-6749(20)30264-5/fulltext
* Both AS1517499 and NT157 from Axon Medchem

Adhyatmika, A., Putri, K. S., Gore, E., Mangnus, K. A., Reker-Smit, C., Schuppan, D., ... & Melgert, B. N. (2020). Osteoprotegerin expression in liver is induced by IL-13 through TGF-β. bioRxiv.
https://www.biorxiv.org/content/10.1101/2020.12.11.421479v1.full

Yang, W. L., Chen, S. Y., Ho, C. Y., & Yen, G. C. (2020). Citrus flavonoids suppress IL-5 and ROS through distinct pathways in PMA/ionomycin-induced EL-4 cells. Food & Function, 11(1), 824-833.
https://pubs.rsc.org/en/content/articlehtml/2020/fo/c9fo02815c

Manson, M. L., Säfholm, J., James, A., Johnsson, A. K., Bergman, P., Al-Ameri, M., ... & Adner, M. (2020). IL-13 and IL-4, but not IL-5 nor IL-17A, induce hyperresponsiveness in isolated human small airways. Journal of Allergy and Clinical Immunology, 145(3), 808-817.
https://www.sciencedirect.com/science/article/pii/S0091674919316185

Gaydosik, A. M., Queen, D. S., Trager, M. H., Akilov, O. E., Geskin, L. J., & Fuschiotti, P. (2020). Genome-wide transcriptome analysis of the STAT6-regulated genes in advanced-stage cutaneous T-cell lymphoma. Blood, 136(15), 1748-1759.
https://ashpublications.org/blood/article/136/15/1748/456039/Genome-wide-transcriptome-analysis-of-the-STAT6

Mendoza-Rodríguez, M. G., Sánchez-Barrera, C. Á., Callejas, B. E., García-Castillo, V., Beristain-Terrazas, D. L., Delgado-Buenrostro, N. L., ... & Terrazas, L. I. (2020). Use of STAT6 phosphorylation inhibitor and trimethylglycine as new adjuvant therapies for 5-fluorouracil in colitis-associated tumorigenesis. International journal of molecular sciences, 21(6), 2130.
https://www.mdpi.com/1422-0067/21/6/2130/htm

Penke, L. R., Ouchi, H., Speth, J. M., Lugogo, N., Huang, Y. J., Huang, S. K., & Peters-Golden, M. (2020). Transcriptional regulation of the IL-13Rα2 gene in human lung fibroblasts. Scientific reports, 10(1), 1-14.
https://www.nature.com/articles/s41598-020-57972-1

2019
Liu, L., Zhu, X., Zhao, T., Yu, Y., Xue, Y., & Zou, H. (2019). Sirt1 ameliorates monosodium urate crystal–induced inflammation by altering macrophage polarization via the PI3K/Akt/STAT6 pathway. Rheumatology, 58(9), 1674-1683.
https://academic.oup.com/rheumatology/article/58/9/1674/5491522?login=true

olde Heuvel, F., Holl, S., Chandrasekar, A., Li, Z., Wang, Y., Rehman, R., ... & Roselli, F. (2019). STAT6 mediates the effect of ethanol on neuroinflammatory response in TBI. Brain, Behavior, and Immunity, 81, 228-246.
https://www.sciencedirect.com/science/article/abs/pii/S0889159119302545

Louca, M., Stylianou, A., Minia, A., Pliaka, V., Alexopoulos, L. G., Gkretsi, V., & Stylianopoulos, T. (2019). Ras suppressor-1 (RSU-1) promotes cell invasion in aggressive glioma cells and inhibits it in non-aggressive cells through STAT6 phospho-regulation. Scientific reports, 9(1), 1-13.
https://www.nature.com/articles/s41598-019-44200-8

Liang, Y., Yi, P., Yuan, D. M. K., Jie, Z., Kwota, Z., Soong, L., ... & Sun, J. (2019). IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis. Cellular & molecular immunology, 16(2), 126-137.
https://www.nature.com/articles/cmi2017147

Dumigan, A., Fitzgerald, M., Santos, J. S. P. G., Hamid, U., O’kane, C. M., McAuley, D. F., & Bengoechea, J. A. (2019). A porcine ex vivo lung perfusion model to investigate bacterial pathogenesis. MBio, 10(6), e02802-19.
https://journals.asm.org/doi/abs/10.1128/mBio.02802-19
 
Miller, M. M., Barik, S., Cattin-Roy, A. N., Ukah, T. K., Hoeman, C. M., & Zaghouani, H. (2019). A new IRF-1–driven apoptotic pathway triggered by IL-4/IL-13 kills neonatal Th1 cells and weakens protection against viral infection. The Journal of Immunology, 202(11), 3173-3186.
https://www.jimmunol.org/content/jimmunol/202/11/3173.full.pdf

Louca, M. A. (2019). In vitro investigation of the role of Ras Suppressor-1 (RSU-1) and Integrin-Linked kinase (ILK) in glioma progression and invasion.
https://gnosis.library.ucy.ac.cy/bitstream/handle/7/64841/Maria_A_Louca_PhD.pdf?sequence=1&isAllowed=y

ХАН, Ё. Х., ЧОН, С., СОН, К. Ю., КИМ, М. Х., & КИМ, Ч. Х. (2019). СПОСОБЫ ЛЕЧЕНИЯ ЛЕЙКОПЕНИИ И ТРОМБОЦИТОПЕНИИ.
https://elibrary.ru/item.asp?id=41277608

Liu, J., Li, Y., Lu, Z., Gu, J., Liang, Y., Huang, E., ... & Yu, H. (2019). Deceleration of glycometabolism impedes IgG‐producing B‐cell‐mediated tumor elimination by targeting SATB 1. Immunology, 156(1), 56-68.
https://onlinelibrary.wiley.com/doi/abs/10.1111/imm.12998

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., ... & Dickinson, R. S. (2019). IL4R Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo  American Journal of Respiratory and Critical Care Medicine, 200(2), 235-246.
https://www.research.ed.ac.uk/portal/files/81125537/rccm.201808_1599oc.pdf

Harris, A. J., Mirchandani, A. S., Lynch, R. W., Murphy, F., Delaney, L., Small, D., ... & Dickinson, R. S. (2019). IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses In Vivo. American journal of respiratory and critical care medicine, (ja).
https://www.atsjournals.org/doi/abs/10.1164/rccm.201808-1599OC

Li, Y., Zhao, C., Liu, J., Lu, Z., Lu, M., Gu, J., & Liu, R. (2019). CD1d highly expressed on DCs reduces lung tumor burden by enhancing antitumor immunity. Oncology reports, 41(5), 2679-2688.
https://www.spandidos-publications.com/or/41/5/2679

Sharba, S., Navabi, N., Padra, M., Persson, J. A., Quintana-Hayashi, M. P., Gustafsson, J. K., ... & Quiding-Järbrink, M. (2019). Interleukin 4 induces rapid mucin transport, increases mucus thickness and quality and decreases colitis and Citrobacter rodentium in contact with epithelial cells. Virulence, 10(1), 97-117.
https://www.tandfonline.com/doi/abs/10.1080/21505594.2019.1573050

Miller, M. M., Barik, S., Cattin-Roy, A. N., Ukah, T. K., Hoeman, C. M., & Zaghouani, H. (2019). A New IRF-1–Driven Apoptotic Pathway Triggered by IL-4/IL-13 Kills Neonatal Th1 Cells and Weakens Protection against Viral Infection. The Journal of Immunology, 202(11), 3173-3186.
http://www.jimmunol.org/content/early/2019/04/16/jimmunol.1800943.abstract

2018
Раецкая, А. А., Калиш, С. В., Лямина, С. В., Малышева, Е. В., Буданова, О. П., Бахтина, Л. Ю., & Малышев, И. Ю. (2018). Репрограммированые in vitro на м3 фенотип макрофаги останавливают рост солидной карциномы in vivo. Патологическая физиология и экспериментальная терапия, 62(1), 41-46.
https://www.pfiet.ru/index.php/pfiet/article/view/914
* S3I204 and AS1517499 from Axon Medchem

Ni, X., Fu, B., Zhang, J., Sun, R. U. I., Tian, Z., & Wei, H. (2018). Cytokine-Based Generation of CD49a+ Eomes−/+ Natural Killer Cell Subsets. Frontiers in immunology, 9.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167425/

SOHN, Ki Young; KIM, Jae Wha. Method for treating paroxysmal nocturnal hemoglobinuria. U.S. Patent Application No 15/775,810, 2018.
https://patents.google.com/patent/US20180296520A1/en

SOHN, Ki Young; KIM, Jae Wha. Method for treating hemolytic uremic syndrome. U.S. Patent Application No 15/775,811, 2018.
https://patents.google.com/patent/US20180325857A1/en

Jacobs, J. R., Greiner, S. P., & Bowdridge, S. A. (2018). Impaired interleukin‐4 signalling promotes establishment of Haemonchus contortus in sheep. Parasite immunology, 40(12), e12597.
https://onlinelibrary.wiley.com/doi/abs/10.1111/pim.12597

Mitamura, Y., Nunomura, S., Nanri, Y., Arima, K., Yoshihara, T., Komiya, K., ... & Izuhara, K. (2018). Hierarchical control of IL-13 signals in lung fibroblasts by STAT6 and SOX11. Journal of Biological Chemistry, jbc-RA117.
http://www.jbc.org/content/early/2018/08/03/jbc.RA117.001364.short

Kim, M. J., Lee, Y. J., Yoon, Y. S., Lim, J. H., Park, E. M., Chong, Y. H., & Kang, J. L. (2018). A STAT6 Inhibitor AS1517499 Reduces Preventive Effects of Apoptotic Cell Instillation on Bleomycin-Induced Lung Fibrosis by Suppressing PPARγ. Cellular Physiology and Biochemistry, 45(5), 1863-1877.
https://www.karger.com/Article/Abstract/487877

Sun, H., Bi, J., Lei, Q., Wan, X., Jiang, T., Wu, C., & Wang, X. (2018). Partial enteral nutrition increases intestinal sIgA levels in mice undergoing parenteral nutrition in a dose-dependent manner. International Journal of Surgery, 49, 74-79.
https://www.sciencedirect.com/science/article/pii/S174391911731484X 
 
Kim, M. J., Lee, Y. J., Yoon, Y. S., Kim, M., Choi, J. H., Kim, H. S., & Kang, J. L. (2018). Apoptotic cells trigger the ABCA1/STAT6 pathway leading to PPAR‐γ expression and activation in macrophages. Journal of leukocyte biology, 103(5), 885-895.
https://jlb.onlinelibrary.wiley.com/doi/abs/10.1002/JLB.2A0817-341RR

Hamid, M. A., Jackson, R. J., Roy, S., Khanna, M., & Ranasinghe, C. (2018). Unexpected involvement of IL‐13 signalling via a STAT6 independent mechanism during murine IgG2a development following viral vaccination. European journal of immunology.
https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.201747463
 
Makita, K., Mikami, Y., Matsuzaki, H., Miyashita, N., Takeshima, H., Noguchi, S., ... & Nagase, T. (2018). Mechanism of Periostin Production in Human Bronchial Smooth Muscle Cells. International archives of allergy and immunology, 175(1-2), 26-35.
https://www.karger.com/Article/Abstract/485892

Casella, G., Colombo, F., Finardi, A., Descamps, H., Ill-Raga, G., Spinelli, A., ... & Furlan, R. (2018). Extracellular Vesicles Containing IL-4 Modulate Neuroinflammation in a Mouse Model of Multiple Sclerosis. Molecular Therapy.
https://www.sciencedirect.com/science/article/pii/S1525001618303101

Hosokawa, Y., Hosokawa, I., Ozaki, K., & Matsuo, T. (2018). Transforming growth factor‐β1 increases C‐C chemokine ligand 11 production in interleukin 4‐stimulated human periodontal ligament cells. Cell biology international.
https://onlinelibrary.wiley.com/doi/abs/10.1002/cbin.11030

QUAIL, Daniela Francis; JOYCE, Johanna Alexandra; BOWMAN, Robert Lyle. Compositions and methods for treatment of glioma. U.S. Patent Application No 15/572,456, 2018.
https://patents.google.com/patent/US20180125852A1/en

Ge, X. N., Bastan, I., Dileepan, M., Greenberg, Y., Ha, S. G., Steen, K. A., ... & Sriramarao, P. (2018). FABP4 regulates eosinophil recruitment and activation in allergic airway inflammation. American Journal of Physiology-Lung Cellular and Molecular Physiology.
https://www.physiology.org/doi/abs/10.1152/ajplung.00429.2017

Liang, Y., Yi, P., Yuan, D. M. K., Jie, Z., Kwota, Z., Soong, L., ... & Sun, J. (2018). IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis. Cellular & molecular immunology.
https://www.nature.com/articles/cmi2017147.pdf?origin=ppub

Ladjemi, M. Z., Gras, D., Dupasquier, S., Detry, B., Lecocq, M., Garulli, C., ... & Pilette, C. (2018). Bronchial Epithelial IgA Secretion Is Impaired in Asthma. Role of IL-4/IL-13. American journal of respiratory and critical care medicine, 197(11), 1396-1409.
https://www.atsjournals.org/doi/abs/10.1164/rccm.201703-0561OC

2017
Wei, X., Nie, S., Liu, H., Sun, J., Liu, J., Li, J., ... & Sun, Y. (2017). Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages. American journal of cancer research, 7(11), 2220.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714751/

Калиш, С. В., Лямина, С. В., Раецкая, А. А., & Малышев, И. Ю. (2017). Репрограммированные М1 макрофаги с ингибированными STAT3, STAT6 и SMAD3 увеличивают продолжительность жизни мышей c экспериментальной карциномой. Патологическая физиология и экспериментальная терапия, 61(2), 4-9.
https://j.iph.ras.ru/index.php/pfiet/article/view/388

 Калиш, С. В., Лямина, С. В., Раецкая, А. А., Буданова, О. П., & Малышев, И. Ю. (2017). Программирование противоопухолевого иммунного ответа in vitro и его использование для остановки пролиферации опухолевых клеток и увеличения продолжительности жизни мышей с карциномой in vivo. Патологическая физиология и экспериментальная терапия, 61(4), 67-73.
https://j.iph.ras.ru/index.php/pfiet/article/view/588
* S3I 204 and AS1517499 were purchased from Axon Medchem
 
Hall, B. M., Balan, V., Gleiberman, A. S., Strom, E., Krasnov, P., Virtuoso, L. P., ... & Leonova, K. I. (2017). p16 (Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli. Aging (Albany NY), 9(8), 1867.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611982/
 
Meng, Y. H., Zhou, W. J., Jin, L. P., Liu, L. B., Chang, K. K., Mei, J., ... & Li, M. Q. (2017). RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell death & disease, 8(10), e3105.
https://www.nature.com/articles/cddis2017505
 
Bao, L., Mohan, G. C., Alexander, J. B., Doo, C., Shen, K., Bao, J., & Chan, L. S. (2017). A molecular mechanism for IL-4 suppression of loricrin transcription in epidermal keratinocytes: implication for atopic dermatitis pathogenesis. Innate immunity, 23(8), 641-647.
http://journals.sagepub.com/doi/abs/10.1177/1753425917732823
 
Harusato, A., Abo, H., Ngo, V. L., Yi, S. W., Mitsutake, K., Osuka, S., ... & Denning, T. L. (2017). IL-36γ signaling controls the induced regulatory T cell–Th9 cell balance via NFκB activation and STAT transcription factors. Mucosal immunology, 10(6), 1455.
https://www.nature.com/articles/mi201721
 
Kälin, S., Becker, M., Ott, V. B., Serr, I., Hosp, F., Mollah, M. M., ... & Scherm, M. G. (2017). A Stat6/Pten axis links regulatory T cells with adipose tissue function. Cell metabolism, 26(3), 475-492.
https://www.sciencedirect.com/science/article/pii/S155041311730493X
 
Barik, S., Miller, M. M., Cattin-Roy, A. N., Ukah, T. K., Chen, W., & Zaghouani, H. (2017). IL-4/IL-13 Signaling Inhibits the Potential of Early Thymic Progenitors To Commit to the T Cell Lineage. The Journal of Immunology, ji1700498.
http://www.jimmunol.org/content/early/2017/09/09/jimmunol.1700498.abstract
 
Miller, M. M. (2017). Interferon regulatory factor 1 (IRF-1) directs IL-4/IL-13 induced death of neonatal Th1 cells (Doctoral dissertation).
https://mospace.umsystem.edu/xmlui/handle/10355/65429
 
Binnemars-Postma, K., Bansal, R., Storm, G., & Prakash, J. (2017). Targeting the Stat6 pathway in tumor-associated macrophages reduces tumor growth and metastatic niche formation in breast cancer. The FASEB Journal, 32(2), 969-978.
https://www.fasebj.org/doi/abs/10.1096/fj.201700629R
 
Yoon, H., & Ko, Y. H. (2017). LMP1+ SLAMF1high cells are associated with drug resistance in Epstein-Barr virus-positive Farage cells. Oncotarget, 8(15), 24621.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421874/
(*Ruxolitinib, lenalidomide, AS1517499 from Axon Medchem)
 
Kalish, S., Lyamina, S., Manukhina, E., Malyshev, Y., Raetskaya, A., & Malyshev, I. (2017). M3 Macrophages Stop Division of Tumor Cells In Vitro and Extend Survival of Mice with Ehrlich Ascites Carcinoma. Medical science monitor basic research, 23, 8-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291087/
(*Stat3 inhibitor S3I204 and Stat6 inhibitor AS1517499 from Axon Medchem)
 
Nappo, G., Handle, F., Santer, F. R., McNeill, R. V., Seed, R. I., Collins, A. T., ... & Erb, H. H. H. (2017). The immunosuppressive cytokine interleukin-4 increases the clonogenic potential of prostate stem-like cells by activation of STAT6 signalling. Oncogenesis, 6(5), e342.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5523058/

Leon-Cabrera, S. A., Molina-Guzman, E., Delgado-Ramirez, Y. G., Vázquez-Sandoval, A., Ledesma-Soto, Y., Pérez-Plasencia, C. G., ... & Ávila-Moreno, F. (2017). Lack of STAT6 attenuates inflammation and drives protection against early steps of colitis-associated colon cancer. Cancer Immunology Research, 5(5), 385-396.
https://www.researchgate.net/profile/Luis_Arias-Romero/publication/315827348_Lack_of_STAT6_attenuates_inflammation_and_drives_protection_against_early_steps_of_colitis-associated_colon_cancer/links/5914b4b7aca27200fe4e8d63/Lack-of-STAT6-attenuates-inflammation-and-drives-protection-against-early-steps-of-colitis-associated-colon-cancer.pdf

Aravamudan, B., Goorhouse, K. J., Unnikrishnan, G., Thompson, M. A., Pabelick, C. M., Hawse, J. R., ... & Sathish, V. (2017). Differential Expression of Estrogen Receptor Variants in Response to Inflammation Signals in Human Airway Smooth Muscle. Journal of cellular physiology, 232(7), 1754-1760.
http://onlinelibrary.wiley.com/doi/10.1002/jcp.25674/full

Philip, K., Mills, T. W., Davies, J., Chen, N. Y., Karmouty-Quintana, H., Luo, F., ... & Eltzschig, H. K. (2017). HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis. The FASEB Journal, fj-201700219R.
http://www.fasebj.org/content/early/2017/07/12/fj.201700219R.abstract
 
Waqas, S. F. H., Hoang, A. C., Lin, Y. T., Ampem, G., Azegrouz, H., Balogh, L., ... & Lim, J. S. (2017). Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages. The Journal of Clinical Investigation, 127(7).
https://www.jci.org/articles/view/90152

2016
Jiang, X., Zha, B., Liu, X., Liu, R., Liu, J., Huang, E., ... & Wang, L. (2016). STAT6 deficiency ameliorates Graves' disease severity by suppressing thyroid epithelial cell hyperplasia. Cell death & disease, 7(12), e2506.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260978/
 
Cheng, E., Zhang, X., Wilson, K. S., Wang, D. H., Park, J. Y., Huo, X., ... & Souza, R. F. (2016). JAK-STAT6 pathway inhibitors block eotaxin-3 secretion by epithelial cells and fibroblasts from esophageal eosinophilia patients: promising agents to improve inflammation and prevent fibrosis in EoE. PloS one, 11(6), e0157376.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157376

Quail, D. F., Bowman, R. L., Akkari, L., Quick, M. L., Schuhmacher, A. J., Huse, J. T., ... & Joyce, J. A. (2016). The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science, 352(6288), aad3018.
http://science.sciencemag.org/content/352/6288/aad3018.full

 Higuchi, H., Shoji, T., Murase, Y., Iijima, S., & Nishijima, K. I. (2016). Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264. Bioscience, biotechnology, and biochemistry, 80(3), 501-509.
http://www.tandfonline.com/doi/abs/10.1080/09168451.2015.1104238

Saito, Y., Azuma, A., Matsuda, K., Kamio, K., Abe, S., & Gemma, A. (2016). Pirfenidone exerts a suppressive effect on CCL18 expression in U937-derived macrophages partly by inhibiting STAT6 phosphorylation. Immunopharmacology and immunotoxicology, 38(6), 464-471.
http://www.tandfonline.com/doi/abs/10.1080/08923973.2016.1247852

Quail, D. F., Bowman, R. L., Akkari, L., Quick, M. L., Schuhmacher, A. J., Huse, J. T., ... & Joyce, J. A. (2016). The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science, 352(6288), aad3018.
http://science.sciencemag.org/content/352/6288/aad3018

Hosokawa, Y., Hosokawa,I., Shindo, S., Ozaki, K., & Matsuo, T. (2016). IL-4 ModulatesCCL11 andCCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells. Cellular Physiology and Biochemistry, 38(1), 153-159.
http://www.karger.com/Article/Abstract/438617 

Jeong, J., Kim, Y. J., Yoon, S. Y., Kim, Y. J., Kim, J. H., Sohn, K. Y., ... & Kim, J. W. (2016). PLAG (1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol) modulates eosinophil chemotaxis by regulatingCCL26 expression from epithelial cells. PloS one, 11(3), e0151758.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151758 

Han, Y. H., Chong, S., Sohn, K. Y., Kim, M. H., & Kim, J. W. (2016). "METHODS FOR TREATING LEUKOPENIA AND THROMBOCYTOPENIA." U.S.Patent No. 20,160,128,966.Washington,DC:U.S.Patent and Trademark Office.
http://www.freepatentsonline.com/y2016/0128966.html 

Aguilar-Hernandez, M. M., Blunt, M. D., Dobson, R., Yeomans, A., Thirdborough, S., Larrayoz, M., ... & Johnson, P. M. (2016). IL-4 enhances expression and function of surface IgM inCLLcells. Blood, blood-2015.
http://www.bloodjournal.org/content/early/2016/03/21/blood-2015-11-682906.abstract 

2015
Kouchi, Z. (2015). Monoacylglycerol lipase promotes Fcγ receptor-mediated phagocytosis in microglia but does not regulate LPS-induced upregulation of inflammatory cytokines. Biochemical and biophysical research communications, 464(2), 603-610.
http://www.sciencedirect.com/science/article/pii/S0006291X15302503
*AS1517499 and 10058-F4 from Axon Medchem

Kiguchi, N., Kobayashi, Y., Saika, F., Sakaguchi, H., Maeda, T., & Kishioka, S. (2015). Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain. Pain, 156(4), 684-693.
http://journals.lww.com/pain/Abstract/2015/04000/Peripheral_interleukin_4_ameliorates_inflammatory.15.aspx 

Yoon, S. Y., Kang, H. B., Ko, Y. E., Shin, S. H., Kim, Y. J., Sohn, K. Y., ... & Kim, J. W. (2015). 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression. Immune network, 15(2), 100-109.
http://synapse.koreamed.org/search.php?where=aview&id=10.4110/in.2015.15.2.100&code=0078IN&vmode=FULL 

Villa, A., Rizzi, N., Vegeto, E., Ciana, P., & Maggi, A. (2015). Estrogen accelerates the resolution of inflammation in macrophagic cells. Scientific reports, 5.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609992/ 

Geskin, L. J., Viragova, S., Stolz, D. B., & Fuschiotti, P. (2015). Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation. Blood, 125(18), 2798-2805.
http://www.bloodjournal.org/content/125/18/2798.abstract 

Kumar, R., Mickael, C., Chabon, J., Gebreab, L., Rutebemberwa, A., Garcia, A. R., ... & Barthel, L. (2015). The causal role of IL-4 and IL-13 in Schistosoma mansoni pulmonary hypertension. American journal of respiratory and critical care medicine, 192(8), 998-1008.
https://scholar.google.nl/scholar?q=as1517499+axon+medchem&hl=en&as_sdt=0%2C5&as_ylo=2015&as_yhi=2015# 

Higuchi, H., Shoji, T., Murase, Y., Iijima, S., & Nishijima, K. I. (2015). Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264. Bioscience, biotechnology, and biochemistry, 1-9.
http://www.tandfonline.com/doi/abs/10.1080/09168451.2015.1104238 

Dames, P., Bergann, T., Fromm, A., Bücker, R., Barmeyer, C., Krug, S. M., ... & Schulzke, J. D. (2015). Interleukin‐13 affects the epithelial sodium channel in the intestine by coordinated modulation ofSTAT6 and p38 MAPK activity. The Journal of Physiology, 593(24), 5269-5282.
http://onlinelibrary.wiley.com/doi/10.1113/JP271156/full 

Su, S., Zhao, Q., He, C., Huang, D., Liu, J., Chen, F., ... &Yao, H. (2015). miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nature communications, 6.
http://www.nature.com/ncomms/2015/151005/ncomms9523/full/ncomms9523.html 

2014
Volpe, E., Pattarini, L., Martinez-Cingolani, C., Meller, S., Donnadieu, M. H., Bogiatzi, S.I., ... & Paronetto, M. P. (2014). Thymic stromal lymphopoietin links keratinocytes and dendritic cell–derived IL-23 in patients with psoriasis. Journal of Allergy and Clinical Immunology, 134(2), 373-381.
http://www.sciencedirect.com/science/article/pii/S0091674914005971 

Ferreira, R., Lively, S., & Schlichter, L. C. (2014). IL-4 type 1 receptor signaling up-regulates KCNN4 expression, and increases the KCa3. 1 current and its contribution to migration of alternative-activated microglia. Front Cell Neurosci, 8(183.10), 3389.
http://file2.selleck.jp/citations/tofacitinib-Fedratinib-Front-Cell-Neurosci-20140822.pdf 

Hui, C. C. K., Murphy, D. M., Neighbour, H., Al‐Sayegh, M., O'Byrne, S., Thong, B., ... & Larché, M. (2014). T cell‐mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells. Clinical & Experimental Allergy, 44(7), 953-964.
http://onlinelibrary.wiley.com/doi/10.1111/cea.12330/full 

Roh, K. B., Kim,I.H., Kim, Y. S., Lee, M., Lee, J. A., Jung, E., & Park, D. (2014). Synephrine inhibits eotaxin-1 expression via theSTAT6 signaling pathway. Molecules, 19(8), 11883-11895.
http://www.mdpi.com/1420-3049/19/8/11883/htm 

John, L. (2014). Mechanismen der Transzytose von Makromolekülen bei Morbus Crohn: Untersuchungen am Zellmodell T84 und an humanen Kolon-Biopsien (Doctoral dissertation, Freie UniversitätBerlin).
http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000097497?lang=de
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