List of publications using AS 1517499 (Axon 1992) purchased from Axon Medchem

(total 31 citations listed from 2014-2017; updated AUGUST-2017) 

2017
Yoon, H., & Ko, Y. H. (2017). LMP1+ SLAMF1high cells are associated with drug resistance in Epstein-Barr virus-positive Farage cells. Oncotarget, 8(15), 24621.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421874/
(*Ruxolitinib, lenalidomide, AS1517499 from Axon Medchem)

Kalish, S., Lyamina, S., Manukhina, E., Malyshev, Y., Raetskaya, A., & Malyshev, I. (2017). M3 Macrophages Stop Division of Tumor Cells In Vitro and Extend Survival of Mice with Ehrlich Ascites Carcinoma. Medical science monitor basic research, 23, 8-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291087/
(*Stat3 inhibitor S3I204 and Stat6 inhibitor AS1517499 from Axon Medchem)

Nappo, G., Handle, F., Santer, F. R., McNeill, R. V., Seed, R. I., Collins, A. T., ... & Erb, H. H. H. (2017). The immunosuppressive cytokine interleukin-4 increases the clonogenic potential of prostate stem-like cells by activation of STAT6 signalling. Oncogenesis, 6(5), e342.

Leon-Cabrera, S. A., Molina-Guzman, E., Delgado-Ramirez, Y. G., Vázquez-Sandoval, A., Ledesma-Soto, Y., Pérez-Plasencia, C. G., ... & Ávila-Moreno, F. (2017). Lack of STAT6 attenuates inflammation and drives protection against early steps of colitis-associated colon cancer. Cancer Immunology Research, 5(5), 385-396.

Aravamudan, B., Goorhouse, K. J., Unnikrishnan, G., Thompson, M. A., Pabelick, C. M., Hawse, J. R., ... & Sathish, V. (2017). Differential Expression of Estrogen Receptor Variants in Response to Inflammation Signals in Human Airway Smooth Muscle. Journal of cellular physiology, 232(7), 1754-1760.

Philip, K., Mills, T. W., Davies, J., Chen, N. Y., Karmouty-Quintana, H., Luo, F., ... & Eltzschig, H. K. (2017). HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis. The FASEB Journal, fj-201700219R.
 
Waqas, S. F. H., Hoang, A. C., Lin, Y. T., Ampem, G., Azegrouz, H., Balogh, L., ... & Lim, J. S. (2017). Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages. The Journal of Clinical Investigation, 127(7).
https://www.jci.org/articles/view/90152

2016
Jiang, X., Zha, B., Liu, X., Liu, R., Liu, J., Huang, E., ... & Wang, L. (2016). STAT6 deficiency ameliorates Graves' disease severity by suppressing thyroid epithelial cell hyperplasia. Cell death & disease, 7(12), e2506.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260978/
 
Cheng, E., Zhang, X., Wilson, K. S., Wang, D. H., Park, J. Y., Huo, X., ... & Souza, R. F. (2016). JAK-STAT6 pathway inhibitors block eotaxin-3 secretion by epithelial cells and fibroblasts from esophageal eosinophilia patients: promising agents to improve inflammation and prevent fibrosis in EoE. PloS one, 11(6), e0157376.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157376

Quail, D. F., Bowman, R. L., Akkari, L., Quick, M. L., Schuhmacher, A. J., Huse, J. T., ... & Joyce, J. A. (2016). The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science, 352(6288), aad3018.
http://science.sciencemag.org/content/352/6288/aad3018.full

Higuchi, H., Shoji, T., Murase, Y., Iijima, S., & Nishijima, K. I. (2016). Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264. Bioscience, biotechnology, and biochemistry, 80(3), 501-509.

Saito, Y., Azuma, A., Matsuda, K., Kamio, K., Abe, S., & Gemma, A. (2016). Pirfenidone exerts a suppressive effect on CCL18 expression in U937-derived macrophages partly by inhibiting STAT6 phosphorylation. Immunopharmacology and immunotoxicology, 38(6), 464-471.
http://www.tandfonline.com/doi/abs/10.1080/08923973.2016.1247852

Quail, D. F., Bowman, R. L., Akkari, L., Quick, M. L., Schuhmacher, A. J., Huse, J. T., ... & Joyce, J. A. (2016). The tumor microenvironment underlies acquired resistance to CSF-1R inhibition in gliomas. Science, 352(6288), aad3018.
http://science.sciencemag.org/content/352/6288/aad3018 

Hosokawa, Y., Hosokawa,I., Shindo, S., Ozaki, K., & Matsuo, T. (2016). IL-4 ModulatesCCL11 andCCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells. Cellular Physiology and Biochemistry, 38(1), 153-159.
http://www.karger.com/Article/Abstract/438617 

Jeong, J., Kim, Y. J., Yoon, S. Y., Kim, Y. J., Kim, J. H., Sohn, K. Y., ... & Kim, J. W. (2016). PLAG (1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol) modulates eosinophil chemotaxis by regulatingCCL26 expression from epithelial cells. PloS one, 11(3), e0151758.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0151758 

Han, Y. H., Chong, S., Sohn, K. Y., Kim, M. H., & Kim, J. W. (2016). "METHODS FOR TREATING LEUKOPENIA AND THROMBOCYTOPENIA." U.S.Patent No. 20,160,128,966.Washington,DC:U.S.Patent and Trademark Office.
http://www.freepatentsonline.com/y2016/0128966.html 

Aguilar-Hernandez, M. M., Blunt, M. D., Dobson, R., Yeomans, A., Thirdborough, S., Larrayoz, M., ... & Johnson, P. M. (2016). IL-4 enhances expression and function of surface IgM inCLLcells. Blood, blood-2015.
http://www.bloodjournal.org/content/early/2016/03/21/blood-2015-11-682906.abstract 

2015
Kouchi, Z. (2015). Monoacylglycerol lipase promotes Fcγ receptor-mediated phagocytosis in microglia but does not regulate LPS-induced upregulation of inflammatory cytokines. Biochemical and biophysical research communications, 464(2), 603-610.

http://www.sciencedirect.com/science/article/pii/S0006291X15302503
*AS1517499 and 10058-F4 from Axon Medchem 

Kiguchi, N., Kobayashi, Y., Saika, F., Sakaguchi, H., Maeda, T., & Kishioka, S. (2015). Peripheral interleukin-4 ameliorates inflammatory macrophage-dependent neuropathic pain. Pain, 156(4), 684-693.
http://journals.lww.com/pain/Abstract/2015/04000/Peripheral_interleukin_4_ameliorates_inflammatory.15.aspx 

Yoon, S. Y., Kang, H. B., Ko, Y. E., Shin, S. H., Kim, Y. J., Sohn, K. Y., ... & Kim, J. W. (2015). 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression. Immune network, 15(2), 100-109.
http://synapse.koreamed.org/search.php?where=aview&id=10.4110/in.2015.15.2.100&code=0078IN&vmode=FULL 

Villa, A., Rizzi, N., Vegeto, E., Ciana, P., & Maggi, A. (2015). Estrogen accelerates the resolution of inflammation in macrophagic cells. Scientific reports, 5.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609992/ 

Geskin, L. J., Viragova, S., Stolz, D. B., & Fuschiotti, P. (2015). Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation. Blood, 125(18), 2798-2805.
http://www.bloodjournal.org/content/125/18/2798.abstract 

Kumar, R., Mickael, C., Chabon, J., Gebreab, L., Rutebemberwa, A., Garcia, A. R., ... & Barthel, L. (2015). The causal role of IL-4 and IL-13 in Schistosoma mansoni pulmonary hypertension. American journal of respiratory and critical care medicine, 192(8), 998-1008.
https://scholar.google.nl/scholar?q=as1517499+axon+medchem&hl=en&as_sdt=0%2C5&as_ylo=2015&as_yhi=2015# 

Higuchi, H., Shoji, T., Murase, Y., Iijima, S., & Nishijima, K. I. (2015). Siglec-9 modulated IL-4 responses in the macrophage cell line RAW264. Bioscience, biotechnology, and biochemistry, 1-9.
http://www.tandfonline.com/doi/abs/10.1080/09168451.2015.1104238 

Dames, P., Bergann, T., Fromm, A., Bücker, R., Barmeyer, C., Krug, S. M., ... & Schulzke, J. D. (2015). Interleukin‐13 affects the epithelial sodium channel in the intestine by coordinated modulation ofSTAT6 and p38 MAPK activity. The Journal of Physiology, 593(24), 5269-5282.
http://onlinelibrary.wiley.com/doi/10.1113/JP271156/full 

Su, S., Zhao, Q., He, C., Huang, D., Liu, J., Chen, F., ... &Yao, H. (2015). miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program. Nature communications, 6.
http://www.nature.com/ncomms/2015/151005/ncomms9523/full/ncomms9523.html 

2014
Volpe, E., Pattarini, L., Martinez-Cingolani, C., Meller, S., Donnadieu, M. H., Bogiatzi, S.I., ... & Paronetto, M. P. (2014). Thymic stromal lymphopoietin links keratinocytes and dendritic cell–derived IL-23 in patients with psoriasis. Journal of Allergy and Clinical Immunology, 134(2), 373-381.http://www.sciencedirect.com/science/article/pii/S0091674914005971 

Ferreira, R., Lively, S., & Schlichter, L. C. (2014). IL-4 type 1 receptor signaling up-regulates KCNN4 expression, and increases the KCa3. 1 current and its contribution to migration of alternative-activated microglia. Front Cell Neurosci, 8(183.10), 3389.
http://file2.selleck.jp/citations/tofacitinib-Fedratinib-Front-Cell-Neurosci-20140822.pdf 

Hui, C. C. K., Murphy, D. M., Neighbour, H., Al‐Sayegh, M., O'Byrne, S., Thong, B., ... & Larché, M. (2014). T cell‐mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells. Clinical & Experimental Allergy, 44(7), 953-964.
http://onlinelibrary.wiley.com/doi/10.1111/cea.12330/full 

Roh, K. B., Kim,I.H., Kim, Y. S., Lee, M., Lee, J. A., Jung, E., & Park, D. (2014). Synephrine inhibits eotaxin-1 expression via theSTAT6 signaling pathway. Molecules, 19(8), 11883-11895.
http://www.mdpi.com/1420-3049/19/8/11883/htm 

John, L. (2014). Mechanismen der Transzytose von Makromolekülen bei Morbus Crohn: Untersuchungen am Zellmodell T84 und an humanen Kolon-Biopsien (Doctoral dissertation, Freie UniversitätBerlin).
http://www.diss.fu-berlin.de/diss/receive/FUDISS_thesis_000000097497?lang=de

 

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