List of publications using Y 27632 dihydrochloride (Axon 1683) purchased from Axon Medchem

(48 publication citations; this is a partial list from 2013-2021)
 
2021
Hall, G. N., Rutten, I., Lammertyn, J., Eberhardt, J., Geris, L., Luyten, F. P., & Papantoniou, I. (2021). Cartilaginous spheroid-assembly design considerations for endochondral ossification: towards robotic-driven biomanufacturing. Biofabrication, 13(4), 045025.
 
Tong, Z., Kwak, E., Aguiar, A., Peng, B., Pouton, C. W., Voelcker, N. H., & Haynes, J. M. (2021). Compartmentalized microfluidic chambers enable long-term maintenance and communication between human pluripotent stem cell-derived forebrain and midbrain neurons. Lab on a Chip, 21(20), 4016-4030.
* Y27632, LDN193189 and SB431652 from Axon Medchem
 
Preisler, L., Habib, A., Shapira, G., Kuznitsov-Yanovsky, L., Mayshar, Y., Carmel-Gross, I., ... & Ben-Yosef, D. (2021). Heterozygous APC germline mutations impart predisposition to colorectal cancer. Scientific reports, 11(1), 1-12.
*Y27632 and LDN193189 from Axon Medchem
 
Bayerl, J., Ayyash, M., Shani, T., Manor, Y. S., Gafni, O., Massarwa, R., ... & Hanna, J. H. (2021). Principles of signaling pathway modulation for enhancing human naive pluripotency induction. Cell Stem Cell.
* Y27632 and 14 other inhibitors from Axon Medchem

Eenjes, E., Buscop-van Kempen, M., Boerema-de Munck, A., Edel, G. G., Benthem, F., de Kreij-de Bruin, L., ... & Rottier, R. J. (2021). SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways. Elife, 10, e57325.
*Y27632 and DAPT from Axon Medchem

Van Beylen, K., Papantoniou, I., & Aerts, J. M. (2021). Microcarrier screening and evaluation for dynamic expansion of human periosteum-derived progenitor cells in a xenogeneic free medium. 
Frontiers in Bioengineering and Biotechnology, 9, 414.

2020
Lito, S., Sidibe, A., Ilmjarv, S., Burda, P., Baumgartner, M., Wehrle-Haller, B., ... & Marteyn, A. (2020). Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors. Cells, 9(12), 2593.

Zorzan, I., Pellegrini, M., Arboit, M., Incarnato, D., Maldotti, M., Forcato, M., ... & Martello, G. (2020). The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs. 
Nature communications, 11(1), 1-16.
* Y27632, A83-01, Sb431542 and LDN193189 from Axon Medchem

Stegen, S., Rinaldi, G., Loopmans, S., Stockmans, I., Moermans, K., Thienpont, B., ... & Carmeliet, G. (2020). Glutamine metabolism controls chondrocyte identity and function. 
Developmental Cell, 53(5), 530-544.

Bayerl, J., Ayyash, M., Shani, T., Manor, Y., Gafni, O., Kalma, Y., ... & Hanna, J. H. (2020). Tripartite inhibition of SRC-WNT-PKC signalling consolidates human naïve pluripotency. 
bioRxiv.
* Y27632 and 10 other inhibitors from Axon Medchem

Castel, G., Meistermann, D., Bretin, B., Firmin, J., Justine, B. L. I. N., Loubersac, S., ... & David, L. (2020). Generation of human induced trophoblast stem cells. 
bioRxiv.
*Y27632 and other 4 inhibitors, CHIR99021, PD0325901, GO6983 and PD173074 from Axon Medchem
 
Castel, G., Meistermann, D., Bretin, B., Firmin, J., Blin, J., Loubersac, S., ... & David, L. (2020). Induction of human trophoblast stem cells from somatic cells and pluripotent stem cells. 
Cell Reports, 33(8), 108419.
* Y27632 and 8 other inhibitors from Axon Medchem

Tournaire, G., Stegen, S., Giacomini, G., Stockmans, I., Moermans, K., Carmeliet, G., & van Gastel, N. (2020). Nestin-GFP transgene labels skeletal progenitors in the periosteum. Bone, 133, 115259.

Groeneveldt, L. C., Herpelinck, T., Maréchal, M., Politis, C., van IJcken, W. F., Huylebroeck, D., ... & Luyten, F. P. (2020). The bone-forming properties of periosteum-derived cells differ between harvest sites. Frontiers in cell and developmental biology, 8.

Teijeira, A., Garasa, S., Gato, M., Alfaro, C., Migueliz, I., Cirella, A., ... & Melero, I. (2020). CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity. Immunity, 52(5), 856-871.

Nilsson Hall, G., Mendes, L. F., Gklava, C., Geris, L., Luyten, F. P., & Papantoniou, I. (2020). Developmentally engineered callus organoid bioassemblies exhibit predictive in vivo long bone healing. Advanced Science, 7(2), 1902295.

van Gastel, N., Stegen, S., Eelen, G., Schoors, S., Carlier, A., Daniëls, V. W., ... & Carmeliet, G. (2020). Lipid availability determines fate of skeletal progenitor cells via SOX9. Nature, 579(7797), 111-117.

2019
Stiers, P. J., Stegen, S., van Gastel, N., Van Looveren, R., Torrekens, S., & Carmeliet, G. (2019). Inhibition of the Oxygen Sensor PHD2 Enhances Tissue‐Engineered Endochondral Bone Formation. Journal of Bone and Mineral Research, 34(2), 333-348.

Gupta, P., Hall, G. N., Geris, L., Luyten, F. P., & Papantoniou, I. (2019). Human Platelet Lysate Improves Bone Forming Potential of Human Progenitor Cells Expanded in Microcarrier‐Based Dynamic Culture. Stem cells translational medicine, 8(8), 810-821.

Potirat, P., Wattanapanitch, M., Viprakasit, V., Kheolamai, P., & Issaragrisil, S. (2019). An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling. Stem cell research, 34, 101344.
 
Preisler, L., Ben‐Yosef, D., & Mayshar, Y. (2019). Adenomatous Polyposis Coli as a Major Regulator of Human Embryonic Stem Cells Self‐Renewal. Stem Cells, 37(12), 1505-1515.

Di Stefano, B., Luo, E. C., Haggerty, C., Aigner, S., Charlton, J., Brumbaugh, J., ... & Hochedlinger, K. (2019). The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis. Cell stem cell, 25(5), 622-638.
* Y27632 and 6 other inhibitors from Axon Medchem
 
Giulitti, S., Pellegrini, M., Zorzan, I., Martini, P., Gagliano, O., Mutarelli, M., ... & Martello, G. (2019). Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics. Nature cell biology, 21(2), 275-286.

Frank, S., Ahuja, G., Bartsch, D., Russ, N., Yao, W., Kuo, J. C. C., ... & Kurian, L. (2019). yylncT defines a class of divergently transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs. Cell stem cell, 24(2), 318-327.
*Y27632 and CHIR99021 from Axon Medchem

Elvassore, N., Martello, G., Giulitti, S., Pellegrini, M., & Gagliano, O. (2019). Human Fibroblast Reprogramming to Naïve Induced Pluripotent Stem Cells in Microfluidics.
*Y27632 and CHIR99021 from Axon Medchem
 
2018
Di Stefano, B., & Hochedlinger, K. Reduced MEK inhibition preserves genomic stability in naïve human ES cells. Protocol Exchange, doi, 10. (2018)
* Y-27632, PD0325901, Gö6983, IM-12, SB590885,  WH-4-023 and CHIR99021 from Axon Medchem

Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., ... & Hanna, J.H. (2018). Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. Cell stem cell. in press
* CHIR99021, PD0325901, GO6983, CGP77675, Y27632, DBZ are all from Axon Medchem
 
Potirat, P., Wattanapanitch, M., Kheolamai, P., & Issaragrisil, S. (2018). Establishment of a human iPSC line (MUSIi007-A) from peripheral blood of normal individual using Sendai viral vectors. Stem Cell Research.
 
Sahakyan, A., Clement, K., Clowers, K. J., Erickson, A. R., Shioda, K., Gygi, S. P., ... & Plath, K. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature Methods. 2018, 15, 732–740.
* Y27632, IM-12, SB590885, WH4-023, CHIR99021, PD0325901 and GO6983 from Axon Medchem.
 
Gupta, P., Geris, L., Luyten, F. P., & Papantoniou, I. (2018). An Integrated Bioprocess for the Expansion and Chondrogenic Priming of Human Periosteum‐Derived Progenitor Cells in Suspension Bioreactors. Biotechnology journal, 13(2), 1700087.
 
Hosokawa, Y., Toyoda, T., Fukui, K., Baden, M. Y., Funato, M., Kondo, Y., ... & Watanabe, A. (2018). Insulin‐producing cells derived from ‘induced pluripotent stem cells’ of patients with fulminant type 1 diabetes: Vulnerability to cytokine insults and increased expression of apoptosis‐related genes. Journal of diabetes investigation, 9(3), 481-493.
* CHIR99021 and Y-27632 from Axon Medchem
 
Vas, W. J., Shah, M., Blacker, T. S., Duchen, M. R., Sibbons, P., & Roberts, S. J. (2018). Decellularized Cartilage Directs Chondrogenic Differentiation: Creation of a Fracture Callus Mimetic. Tissue Engineering Part A.
 
2017
Hopkinson, B. M., Klitgaard, M. C., Petersen, O. W., Villadsen, R., Rønnov-Jessen, L., & Kim, J. (2017). Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype. Oncotarget, 8(6), 10580.
* Y27632 and SB431542 from Axon Medchem
 
Stolarczyk, M., Veit, G., Schnur, A., Veltman, M., Lukacs, G. L., & Scholte, B. J. (2017). Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity. American Journal of Physiology-Lung Cellular and Molecular Physiology, 314(4), L555-L568.
 
Rademacher, S., Verheijen, B. M., Hensel, N., Peters, M., Bora, G., Brandes, G., ... & van der Pol, W. L. (2017). Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA). Human molecular genetics, 26(20), 3946-3959.
* Y27632 and SB431542 from Axon Medchem
 
Rademacher, S. (2017). Cytoskeletal dysregulation in the motoneuron disease Spinal Muscular Atrophy (SMA) (Doctoral dissertation, Tierärztliche Hochschule Hannover).
* Y27632 and SB431542 from Axon Medchem
 
2016
Morsing, M., Klitgaard, M. C., Jafari, A., Villadsen, R., Kassem, M., Petersen, O. W., & Rønnov-Jessen, L. (2016). Evidence of two distinct functionally specialized fibroblast lineages in breast stroma. Breast Cancer Research, 18(1), 108.
 
Lambrechts, T., Papantoniou, I., Rice, B., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2016). Large-scale progenitor cell expansion for multiple donors in a monitored hollow fibre bioreactor. Cytotherapy, 18(9), 1219-1233.
 
Lambrechts, T., Papantoniou, I., Viazzi, S., Bovy, T., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2016). Evaluation of a monitored multiplate bioreactor for large-scale expansion of human periosteum derived stem cells for bone tissue engineering applications. Biochemical engineering journal, 108, 58-68.
 
Frank, P., & Jean-Marie, A. Large-scale progenitor cell expansion for multiple donors in a monitored hollow fibre bioreactor.
 
Tieng, V., Cherpin, O., Gutzwiller, E., Zambon, A. C., Delgado, C., Salmon, P., ... & Krause, K. H. (2016). Elimination of proliferating cells from CNS grafts using a Ki67 promoter-driven thymidine kinase. Molecular Therapy-Methods & Clinical Development, 3, 16069
 
Harschnitz, O., van den Berg, L. H., Johansen, L. E., Jansen, M. D., Kling, S., Vieira de Sá, R., ... & Pasterkamp, R. J. (2016). Autoantibody pathogenicity in a multifocal motor neuropathy induced pluripotent stem cell–derived model. Annals of neurology.
*Y27632 and SB431542 from Axon Medchem
 
Pathak, J. L., Verschueren, P., Lems, W. F., Bravenboer, N., Klein-Nulend, J., Bakker, A. D., & Luyten, F. P. (2016). Serum of patients with active rheumatoid arthritis inhibits differentiation of osteochondrogenic precursor cells. Connective tissue research, 57(3), 226-235.
 
2015
Kirkeby, A., Nelander, J., & Parmar, M. (2015). Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Developing stem cell-based therapies for neural repair.
*SB431542 and Y27632 from Axon Medchem
 
Lambrechts, T., Papantoniou, I., Viazzi, S., Bovy, T., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2015). Evaluation of a monitored multiplate bioreactor for large-scale expansion of human periosteum derived stem cells for bone tissue engineering applications. Biochemical Engineering Journal.
 
2014
Hartley, B. J., Fabb, S. A., Finnin, B. A., Haynes, J. M., & Pouton, C. W. (2014). Zinc-finger nuclease enhanced gene targeting in human embryonic stem cells. JoVE (Journal of Visualized Experiments), (90), e51764-e51764.
 
de Esch, Celine EF, Mehrnaz Ghazvini, Friedemann Loos, Nune Schelling-Kazaryan, W. Widagdo, Shashini T. Munshi, Erik van der Wal et al. "Stem Cell Reports." Epigenetic Characterization of the FMR1 Promoter in Induced Pluripotent Stem Cells from Human Fibroblasts Carrying an Unmethylated Full Mutation.
* CHIR99021, PD0325901, SB203580, Y27632 were procured from Axon Medchem.
 
2013
Gafni, O., Weinberger, L., Mansour, A. A., Manor, Y. S., Chomsky, E., Ben-Yosef, D., ... & Hanna, J.H. (2013). Derivation of novel human ground state naive pluripotent stem cells. Nature, 504(7479), 282-286. (Cited by 292 until 6/6/16)
*CHIR99021, PD0325901, SB202190, BIRB796, Y27632 from Axon Medchem
 
(*This is an incomplete list of Y 27632 used from Axon Medchem.)
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