List of publications using Dasatinib (Axon 1392) purchased from Axon Medchem
(Total of 30 publication citations, incomplete overview from 2010 up to March 2020)
2020
Kwon, M., Kim, C. G., Lee, H., Cho, H., Kim, Y., Lee, E. C., ... & Song, I. C. (2020). PD-1 Blockade Reinvigorates Bone Marrow CD8+ T Cells from Patients with Multiple Myeloma in the Presence of TGFβ Inhibitors. Clinical Cancer Research.
https://clincancerres.aacrjournals.org/content/early/2020/02/06/1078-0432.CCR-19-0267.abstract
Magnin, M., Guillaume, P., Coukos, G., Harari, A., & Schmidt, J. (2020). High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers. In Methods in Enzymology (Vol. 631, pp. 21-42). Academic Press.
https://www.sciencedirect.com/science/article/pii/S0076687919301788
2019
Park, J., Kwon, M., Kim, K. H., Kim, T. S., Hong, S. H., Kim, C. G., ... & Chang, J. H. (2019). Immune checkpoint inhibitor-induced reinvigoration of tumor-infiltrating CD8+ T cells is determined by their differentiation status in glioblastoma. Clinical Cancer Research, 25(8), 2549-2559.
https://clincancerres.aacrjournals.org/content/25/8/2549.full
Yeo, L., Pujol‐Autonell, I., Baptista, R., Eichmann, M., Kronenberg‐Versteeg, D., Heck, S., ... & Toppari, J. (2019). Circulating β cell‐specific CD8+ T cells restricted by high‐risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes. Clinical & Experimental Immunology.
https://onlinelibrary.wiley.com/doi/abs/10.1111/cei.13391
Serra, P., Garabatos, N., Singha, S., Fandos, C., Garnica, J., Solé, P., ... & Ortega, M. (2019). Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules. Nature Communications, 10(1), 1-14.
https://www.nature.com/articles/s41467-019-12902-2
Kefalakes, H., Koh, C., Sidney, J., Amanakis, G., Sette, A., Heller, T., & Rehermann, B. (2019). Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection. Gastroenterology, 156(6), 1805-1819.
https://www.sciencedirect.com/science/article/abs/pii/S0016508519300952
2018
Richmond, J. M., Strassner, J. P., Zapata, L., Garg, M., Riding, R. L., Refat, M. A., ... & Pandya, A. G. (2018). Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo. Science translational medicine, 10(450), eaam7710.
https://stm.sciencemag.org/content/10/450/eaam7710?rss\u003d1
Kim, H. D., Song, G. W., Park, S., Jung, M. K., Kim, M. H., Kang, H. J., ... & Moon, D. B. (2018). Association between expression level of PD1 by tumor-infiltrating CD8+ T cells and features of hepatocellular carcinoma. Gastroenterology, 155(6), 1936-1950.Magnin, M., Guillaume, P., Coukos, G., Harari, A., & Schmidt, J. (2020). High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers. In Methods in Enzymology (Vol. 631, pp. 21-42). Academic Press.
https://www.sciencedirect.com/science/article/pii/S0076687919301788
2019
Park, J., Kwon, M., Kim, K. H., Kim, T. S., Hong, S. H., Kim, C. G., ... & Chang, J. H. (2019). Immune checkpoint inhibitor-induced reinvigoration of tumor-infiltrating CD8+ T cells is determined by their differentiation status in glioblastoma. Clinical Cancer Research, 25(8), 2549-2559.
https://clincancerres.aacrjournals.org/content/25/8/2549.full
Yeo, L., Pujol‐Autonell, I., Baptista, R., Eichmann, M., Kronenberg‐Versteeg, D., Heck, S., ... & Toppari, J. (2019). Circulating β cell‐specific CD8+ T cells restricted by high‐risk HLA class I molecules show antigen experience in children with and at risk of type 1 diabetes. Clinical & Experimental Immunology.
https://onlinelibrary.wiley.com/doi/abs/10.1111/cei.13391
Serra, P., Garabatos, N., Singha, S., Fandos, C., Garnica, J., Solé, P., ... & Ortega, M. (2019). Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules. Nature Communications, 10(1), 1-14.
https://www.nature.com/articles/s41467-019-12902-2
Kefalakes, H., Koh, C., Sidney, J., Amanakis, G., Sette, A., Heller, T., & Rehermann, B. (2019). Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection. Gastroenterology, 156(6), 1805-1819.
https://www.sciencedirect.com/science/article/abs/pii/S0016508519300952
2018
Richmond, J. M., Strassner, J. P., Zapata, L., Garg, M., Riding, R. L., Refat, M. A., ... & Pandya, A. G. (2018). Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo. Science translational medicine, 10(450), eaam7710.
https://stm.sciencemag.org/content/10/450/eaam7710?rss\u003d1
https://www.sciencedirect.com/science/article/abs/pii/S0016508518348972
Collins, R. J., Morgan, L. D., Owen, S., Ruge, F., Jiang, W. G., & Sanders, A. J. (2018). Mechanistic insights of epithelial protein lost in neoplasm in prostate cancer metastasis. International journal of cancer, 143(10), 2537-2550.
https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.31786
https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.31786
Yeo, L., Woodwyk, A., Sood, S., Lorenc, A., Eichmann, M., Pujol-Autonell, I., ... & Tungatt, K. (2018). Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes. The Journal of clinical investigation, 128(8), 3460-3474.
Dolton, G., Zervoudi, E., Ruis, C., Wall, A., Thomas, H., Fuller, A., ... & Chudakov, D. M. (2018). Optimised peptide-MHC multimer protocols for detection and isolation of autoimmune T-cells. Frontiers in immunology, 9, 1378.
https://www.frontiersin.org/articles/10.3389/fimmu.2018.01378/full
https://www.frontiersin.org/articles/10.3389/fimmu.2018.01378/full
Richmond, J. M., Strassner, J. P., Zapata, L., Garg, M., Riding, R. L., Refat, M. A., ... & Pandya, A. G. (2018). Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo. Science translational medicine, 10(450), eaam7710.
Angeletti, D., Kosik, I., Yewdell, W. T., Boudreau, C. M., Mallajosyula, V. V., Chambers, M., ... & Chaudhuri, J. (2018). Outflanking Immunodominance to Target Subdominant Broadly Neutralizing Epitopes. bioRxiv, 346437.
Tungatt, K., Dolton, G., Morgan, S. B., Attaf, M., Fuller, A., Whalley, T., ... & Hammond, J. A. (2018). Induction of influenza-specific local CD8 T-cells in the respiratory tract after aerosol delivery of vaccine antigen or virus in the Babraham inbred pig. PLoS pathogens, 14(5), e1007017.
2017
Cole, D. K., Fuller, A., Dolton, G., Zervoudi, E., Legut, M., Miles, K., ... & Bridgeman, J. S. (2017). Dual Molecular Mechanisms govern escape at immunodominant hla a2-restricted hiV epitope. Frontiers in immunology, 8, 1503.
Meel, M. H., Sewing, A. C. P., Waranecki, P., Metselaar, D. S., Wedekind, L. E., Koster, J., ... & Hulleman, E. (2017). Culture methods of diffuse intrinsic pontine glioma cells determine response to targeted therapies. Experimental cell research, 360(2), 397-403.
Min, S., Lim, Y. S., Shin, D., Park, C., Park, J. B., Kim, S., ... & Hwang, S. B. (2017). Abl tyrosine kinase regulates hepatitis C virus entry. Frontiers in microbiology, 8, 1129.
* Imatinib and dasatinib from Axon Medchem
Mishall, K. M., Beadnell, T. C., Kuenzi, B. M., Klimczak, D. M., Superti-Furga, G., Rix, U., & Schweppe, R. E. (2017). Sustained activation of the AKT/mTOR and MAP kinase pathways mediate resistance to the Src inhibitor, dasatinib, in thyroid cancer. Oncotarget, 8(61), 103014.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732707/
*Dasatinib and bosutinib from Axon Medchem
2016
FAUSTMAN, Denise L. Methods of identifying subjects responsive to treatment for an autoimmune disease and compositions for treating the same. U.S. Patent Application No 15/027,757, 2016.
2015
Motozono, C., Pearson, J. A., De Leenheer, E., Rizkallah, P. J., Beck, K., Trimby, A., ... & Cole, D. K. (2015). Distortion of the major histocompatibility complex class I binding groove to accommodate an insulin-derived 10-mer peptide. Journal of Biological Chemistry, 290(31), 18924-18933.
http://www.jbc.org/content/290/31/18924.short
Azizi, G., Goudarzvand, M., Afraei, S., Sedaghat, R., & Mirshafiey, A. (2015). Therapeutic effects of dasatinib in mouse model of multiple sclerosis. Immunopharmacology and immunotoxicology, 37(3), 287-294.
https://www.tandfonline.com/doi/abs/10.3109/08923973.2015.1028074
Babad, J., Mukherjee, G., Follenzi, A., Ali, R., Roep, B. O., Shultz, L. D., ... & DiLorenzo, T. P. (2015). Generation of β cell‐specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen‐transgenic mice. Clinical & Experimental Immunology, 179(3), 398-413.
https://onlinelibrary.wiley.com/doi/full/10.1111/cei.12465
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., ... & Godkin, A. J. (2015). Antibody stabilization of peptide–MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. The Journal of Immunology, 194(1), 463-474.
https://www.jimmunol.org/content/jimmunol/194/1/463.full.pdf
Motozono, C., Pearson, J. A., De Leenheer, E., Rizkallah, P. J., Beck, K., Trimby, A., ... & Cole, D. K. (2015). Distortion of the MHC class I binding groove to accommodate an insulin-derived 10-mer peptide. Journal of Biological Chemistry, jbc-M114.
Motozono, C., Pearson, J. A., De Leenheer, E., Rizkallah, P. J., Beck, K., Trimby, A., ... & Cole, D. K. (2015). Distortion of the major histocompatibility complex class I binding groove to accommodate an insulin-derived 10-mer peptide. Journal of Biological Chemistry, 290(31), 18924-18933.
http://www.jbc.org/content/290/31/18924.short
Azizi, G., Goudarzvand, M., Afraei, S., Sedaghat, R., & Mirshafiey, A. (2015). Therapeutic effects of dasatinib in mouse model of multiple sclerosis. Immunopharmacology and immunotoxicology, 37(3), 287-294.
https://www.tandfonline.com/doi/abs/10.3109/08923973.2015.1028074
Babad, J., Mukherjee, G., Follenzi, A., Ali, R., Roep, B. O., Shultz, L. D., ... & DiLorenzo, T. P. (2015). Generation of β cell‐specific human cytotoxic T cells by lentiviral transduction and their survival in immunodeficient human leucocyte antigen‐transgenic mice. Clinical & Experimental Immunology, 179(3), 398-413.
https://onlinelibrary.wiley.com/doi/full/10.1111/cei.12465
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., ... & Godkin, A. J. (2015). Antibody stabilization of peptide–MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. The Journal of Immunology, 194(1), 463-474.
https://www.jimmunol.org/content/jimmunol/194/1/463.full.pdf
Motozono, C., Pearson, J. A., De Leenheer, E., Rizkallah, P. J., Beck, K., Trimby, A., ... & Cole, D. K. (2015). Distortion of the MHC class I binding groove to accommodate an insulin-derived 10-mer peptide. Journal of Biological Chemistry, jbc-M114.
Pearson, J. A., & Wong, F. S. (2015). Identification of Islet Antigen-Specific CD8 T Cells Using MHCI-Peptide Tetramer Reagents in the Non Obese Diabetic (NOD) Mouse Model of Type 1 Diabetes. In Type-1 Diabetes (pp. 119-125). Humana Press, New York, NY.
Dolton, G., Tungatt, K., Lloyd, A., Bianchi, V., Theaker, S. M., Trimby, A., ... & Thor Straten, P. (2015). More tricks with tetramers: a practical guide to staining T cells with peptide–MHC multimers. Immunology, 146(1), 11-22.
Holland, C. J., Dolton, G., Scurr, M., Ladell, K., Schauenburg, A. J., Miners, K., ... & Godkin, A. J. (2015). Enhanced Detection of Antigen-Specific CD4+ T Cells Using Altered Peptide Flanking Residue Peptide–MHC Class II Multimers. The Journal of Immunology, 1402787.
http://www.jimmunol.org/content/early/2015/11/07/jimmunol.1402787.short
2014
Dolton, G., Lissina, A., Skowera, A., Ladell, K., Tungatt, K., Jones, E., ... & Godkin, A. J. (2014). Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen‐specific T cells. Clinical & Experimental Immunology, 177(1), 47-63.
https://onlinelibrary.wiley.com/doi/full/10.1111/cei.12339
2011
2014
Dolton, G., Lissina, A., Skowera, A., Ladell, K., Tungatt, K., Jones, E., ... & Godkin, A. J. (2014). Comparison of peptide–major histocompatibility complex tetramers and dextramers for the identification of antigen‐specific T cells. Clinical & Experimental Immunology, 177(1), 47-63.
https://onlinelibrary.wiley.com/doi/full/10.1111/cei.12339
2011
Burger, D. E., Wang, L., Ban, L., Okubo, Y., Kühtreiber, W. M., Leichliter, A. K., & Faustman, D. L. (2011). Novel automated blood separations validate whole cell biomarkers. PloS one, 6(7), e22430.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022430
2010
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022430
2010
Burkhard, K., & Shapiro, P. (2010). Use of inhibitors in the study of MAP kinases. In MAP Kinase Signaling Protocols (pp. 107-122). Humana Press, Totowa, NJ.
https://link.springer.com/protocol/10.1007/978-1-60761-795-2_6
* Dasatinib and Imatinib etc, from Axon Medchem
https://link.springer.com/protocol/10.1007/978-1-60761-795-2_6
* Dasatinib and Imatinib etc, from Axon Medchem