List of publications using BX 795 (Axon 1390) purchased from Axon Medchem 

(Total 24 publication citations updated until May 2016)

2015
Pillai, Smitha, et al. "Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis." Nature communications 6 (2015).

http://www.nature.com/ncomms/2015/151210/ncomms10072/full/ncomms10072.html 

Keifer, Joyce, and Zhaoqing Zheng. "Coincidence detection in a neural correlate of classical conditioning is initiated by bidirectional 3‐phosphoinositide‐dependent kinase‐1 signalling and modulated by adenosine receptors." The Journal of physiology 593.7 (2015): 1581-1595.
*BX912 and BX795 were purchased from Axon Medchem.
 
Awuh, Jane Atesoh, et al. "Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages." Proceedings of the National Academy of Sciences 112.31 (2015): E4272-E4280.
 
di Blasio, Laura, et al. "PDK1 regulates focal adhesion disassembly by modulating endocytosis of αvβ3 integrin." Journal of cell science 128.5 (2015): 863-877.
 
di Blasio, Laura, et al. "PDK1 regulates focal adhesion disassembly through modulation of αvβ3 integrin endocytosis." J Cell Sci (2015): jcs-149294.
 
Chau, Tieu-Lan, et al. "A Role for APPL1 in TLR3/4-Dependent TBK1 and IKKε Activation in Macrophages." The Journal of Immunology 194.8 (2015): 3970-3983.
* BX795, U0126, and GSK1120212 inhibitors were from Axon Medchem.
 
2014
Dieterle, Alexandra Maria, et al. "PDK1 controls upstream PI3K expression and PIP3 generation." Oncogene 33.23 (2014): 3043-3053.
 
Parsons, K. S., A. C. Hsu, and P. A. B. Wark. "TLR3 and MDA5 signalling, although not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection." Clinical & Experimental Allergy 44.1 (2014): 91-101.
 
Deng, Tao, et al. "shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer." Cancer research 74.7 (2014): 2119-2130.
 
Shanmugasundaram, Karthigayan, et al. "The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling." Journal of Biological Chemistry 289.35 (2014): 24691-24699.
 
Lee, Mark Nackyoung, and Nir Hacohen. "Methods relating to dna-sensing pathway related conditions." U.S. Patent Application No. 14/676,933.
 
Rajasekaran, Vidya. Tissue Transglutaminase (TG2) is a potential therapeutic target in the treatment of chemoresistant breast cancer. Diss. Aston University, 2014.

2013
METHODS AND COMPOSITIONS FOR TREATING CANCER.
Q Yu, J Tan - US Patent 20,130,123,328, 2013.
Read more: http://www.freepatentsonline.com/y2013/0123328.html 

Hyaluronan fragments induce IFNbeta via a novel TLR4-TRIF-TBK1-IRF3-dependent pathway. 
KE Black, SL Collins, RS Hagan, MJ Hamblin, Y Chan-Li, RW Hallowell, JD Powell & MR Horton. 
J. Inflam, 2013, 10(1), 23. doi:10.1186/1476-9255-10-23
Read more: http://www.journal-inflammation.com/content/10/1/23/abstract 

PDK1 Signaling Towards PLK1-Myc Activation Confers Oncogenic Transformation and Tumor Initiating Cell Activation and Resistance to mTOR-targeted Therapy.
J Tan, Z Li, PL Lee, P Guan, MY Aau, ST Lee, M Feng, CZ Lim, EYJ Lee, ZN Wee, YC Lim, RKM Karuturi and Q Yu.

Cancer Discovery, Published Online July 25, 2013.
Read more: http://www.ncbi.nlm.nih.gov/pubmed/23887393
... 60 inhibitors including BX795 were purchased from Axon Medchem

TLR3 and MDA5 signalling though not expression, is impaired in asthmatic epithelial cells in response to rhinovirus infection.
KS Parsons, AC Hsu, PAB Wark - Clin. & Exp. Allergy, 2013.  DOI: 10.1111/cea.12218.
Read more: http://onlinelibrary.wiley.com/doi/10.1111/cea.12218/abstract 

2012
3-Phosphoinositide-Dependent Kinase 1 Controls Breast Tumor Growth in a Kinase-Dependent but Akt-Independent Manner1,2.
PA Gagliardi, L di Blasio, F Orso, G Seano, R Sessa, D Taverna, F Bussolino, L Primo.
Neoplasia. 2012, 14 (8), 719–731.   PMCID: PMC3431179   

Phosphorylation of microtubule-associated protein tau by AMPK-related kinases.
H Yoshida, M Goedert.
J Neurochem. 2012, 120 (1), 165–176.    DOI: 10.1111/j.1471-4159.2011.07523.x 

Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function.
X Gao, D Chaturvedi, TB Patel.
Mol. Biol. Cell, 2012, 23 (3), 503-515.  doi: 10.1091/mbc.E11-07-0658 

2011
High-throughput RNAi screening reveals novel regulators of telomerase.
MA Cerone, DJ Burgess, C Naceur-Lombardelli, CJ Lord, A Ashworth.
Cancer Res. 2011, 71, 3328. doi: 10.1158/0008-5472.CAN-10-2734 

The Protein Kinase IKKε Is a Potential Target for the Treatment of Inflammatory Hyperalgesia.
CV Möser, K Kynast, K Baatz, OQ Russe, N Ferreirós, H Costiuk, R Lu, A Schmidtko, I Tegeder, G Geisslinger, E Niederberger.
J. Immunol. 2011, 187 (5), 2617-2625. doi: 10.4049/jimmunol.1004088   

PKC‐dependent endocytosis of the Helicobacter pylori vacuolating cytotoxin in primary T lymphocytes.
X Sewald, L Jiménez‐Soto, R Haas.
Cellular Microbiol. 2011, 13 (3), 482–496.  DOI: 10.1111/j.1462-5822.2010.01551.x 

2010
Specification of the NF-κB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKKε.
R Moreno, JM Sobotzik, C Schultz, M. Lienhard Schmitz.
Nucl. Acids Res. 2010, 38 (18), 6029-6044. doi: 10.1093/nar/gkq439

Nature and Duration of Growth Factor Signaling through Receptor Tyrosine Kinases Regulates HSV-1 Latency in Neurons.
V Camarena, M Kobayashi, JY Kim, P Roehm, R Perez, J Gardner, AC Wilson, I Mohr, MV Chao.
Cell Host & Microbe. 2010, 8 (4), 320-330.
http://www.sciencedirect.com/science/article/pii/S1931312810003094 

 
(This is an incomplete list, updated JUNE-2016)
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