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PLH1215
- AVIL inhibitor compound A
Axon 4473
Recently added
CAS:
1332084-64-6
Purity:
99%
- Soluble in 0.1N HCl(aq), DMSO and EtOH
- MF: C19H26N4O
- MW: 326.44
Description
PLH1215 is a first-in-class BBB-permeable and orally bioavailable AVIL inhibitor.
Key Features
- First-in-class AVIL (advillin) inhibitor
- BBB-permeable compound
- Orally bioavailable
- Targets the actin-binding protein AVIL
- Useful tool compound for glioblastoma research
Applications
- AVIL and advillin biology research
- Glioblastoma and brain cancer studies
- Actin cytoskeleton signaling research
- Cancer cell migration and invasion studies
- CNS-targeted drug discovery research
More Information
| Parent CAS No. | 1332084-64-6 |
|---|---|
| Chemical Name | (1-(2-Amino-4-pyrimidinyl)-3-(3-phenylpropyl)-3-piperidyl)methanol |
| SMILES | C1=CC(N2CC(CCCC3=CC=CC=C3)(CO)CCC2)=NC(N)=N1 |
| InChi | InChI=1S/C19H26N4O/c20-18-21-12-9-17(22-18)23-13-5-11-19(14-23,15-24)10-4-8-16-6-2-1-3-7-16/h1-3,6-7,9,12,24H,4-5,8,10-11,13-15H2,(H2,20,21,22) |
| InChiKey | DTYLCARBXSKICY-UHFFFAOYSA-N |
| CID | 56750508 |
| Short Description | AVIL inhibitor |
