Ziftomenib
- KO-539
Axon 4273
CAS:
2134675-36-6
- Optical Purity: 98
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C33H42F3N9O2S2
- MW: 717.87
Description
Ziftomenib is an orally active small molecule inhibitor targeting menin-KMT2A/MLL protein-protein interaction.
More Information
| Parent CAS No. | 2134675-36-6 |
|---|---|
| Chemical Name | (S)-4-Methyl-5-((4-(2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl)methyl)-1-(2-(4-(methylsulfonyl)piperazin-1-yl)propyl)-1H-indole-2-carbonitrile |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C1C=C(CN2CCC(NC3N=C(NC)N=C4SC(CC(F)(F)F)=CC=34)CC2)C(C)=C2C=C(C#N)N(C[C@H](C)N3CCN(S(C)(=O)=O)CC3)C=12 |&1:36,r| |
| MFCD | N.A. |
| InChi | N.A. |
| InChiKey | N.A. |
| CID | N.A. |
| Short Description | menin-MLL interaction inhibitor |
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