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KIN1148

Name: KIN1148
SKU: 4063

Axon 4063

CAS: 1428729-56-9

Purity: 99%

Soluble in DMSO

MF: C19H11N3OS2
MW: 361.44

Description

KIN1148 is an interferon regulatory factor 3 (IRF3) agonist and induced dose-dependent IRF3 nuclear translocation and specific activation of IRF3-responsive promoters. Influenza vaccine adjuvant.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	1428729-56-9
Chemical Name	N-([1,3]Thiazolo[5,4-e][1,3]benzothiazol-2-yl)naphthalene-2-carboxamide
MFCD	MFCD28371902
Short Description	IRF3 agonist

KIN1148 IRF3 agonist KIN 1148 KIN-1148 CAS 1428729-56-9 Axon Medchem Axon 4063 Innate immune system RLR Inhibitor Receptors Vaccine adjuvant Innate immune transcriptional program RIG-I-like receptor pathway RLR Influenza Supplier Vendor

References

P Probst et al. A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response. Vaccine. 2017 Apr 4;35(15):1964-1971.

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KIN1148

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