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Ropidoxuridine
- IPdR - 1-(2-Deoxy-β-D-ribofuranosyl)-5-iodo-2-pyrimidinone
Axon 3953
CAS:
93265-81-7
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: C9H11IN2O4
- MW: 338.1
Description
Ropidoxuridine is an orally available, halogenated thymidine (TdR) analog and is a potential radiosensitizer for use in human tumors. Ropidoxuridine is a prodrug that is efficiently converted to IUdR (5-iodo-2'-deoxyuridine), an intravenous radiosensitizer by a hepatic aldehyde oxidase.
More Information
| Parent CAS No. | 93265-81-7 |
|---|---|
| Chemical Name | 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one |
| SMILES | [C@@H]1(O)[C@@H](CO)O[C@@H](N2C(=O)N=CC(I)=C2)C1 |&1:0,2,6,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C9H11IN2O4/c10-5-2-11-9(15)12(3-5)8-1-6(14)7(4-13)16-8/h2-3,6-8,13-14H,1,4H2/t6-,7+,8+/m0/s1 |
| InChiKey | XIJXHOVKJAXCGJ-XLPZGREQSA-N |
| CID | 9840777 |
| Short Description | Thymidine analog |
