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Vistonuridine
- Uridine triacetate - Triacetyluridine - TAU
Axon 3362
CAS:
4105-38-8
- Optical Purity: Optically pure
- Soluble in water, 0.1N HCl(aq) and DMSO
- MF: C15H18N2O9
- MW: 370.31
Description
Vistonuridine is a prodrug of uridine. The acetyl groups of Vistonuridine increase the lipophilicity of uridine, thus enhancing its transport from the gastrointestinal tract to the blood stream and its reabsorption from the renal tubules, while rendering Vistonuridine resistant to catabolism by UrdPase.
More Information
| Parent CAS No. | 4105-38-8 |
|---|---|
| Chemical Name | (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
| SMILES | [C@@H]1(OC(=O)C)[C@H](OC(C)=O)[C@@H](COC(C)=O)O[C@H]1N1C(=O)NC(=O)C=C1 |&1:0,5,10,17,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1 |
| InChiKey | AUFUWRKPQLGTGF-FMKGYKFTSA-N |
| CID | 20058 |
| Short Description | Uridine prodrug |
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