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NIBR189

Axon 3231
CAS:  1599432-08-2
Purity:  99%
  • Soluble in DMSO
  • MF:  C21H21BrN2O3
  • MW:  429.31

Description

NIBR189 is a potent and selective EBI2 antagonist with IC50 values of 11 nM and 15 nM for hEBI2 and mEBI2, respectively. Moreover, NIBR189 exhibits pharmacokinetic properties which should allow use for in vitro and in vivo experiments.

More Information

Parent CAS No. 1599432-08-2
Chemical Name (E)-3-(4-Bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one
SMILES C1C=C(/C=C/C(N2CCN(C(C3C=CC(OC)=CC=3)=O)CC2)=O)C=CC=1Br
MFCD N.A.
InChi InChI=1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+
InChiKey OFHXXBRBGWUOHR-NYYWCZLTSA-N
CID 36295259
Short Description EBI-2 antagonist

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