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NIBR189
Axon 3231
CAS:
1599432-08-2
Purity:
99%
- Soluble in DMSO
- MF: C21H21BrN2O3
- MW: 429.31
Description
NIBR189 is a potent and selective EBI2 antagonist with IC50 values of 11 nM and 15 nM for hEBI2 and mEBI2, respectively. Moreover, NIBR189 exhibits pharmacokinetic properties which should allow use for in vitro and in vivo experiments.
More Information
| Parent CAS No. | 1599432-08-2 |
|---|---|
| Chemical Name | (E)-3-(4-Bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one |
| SMILES | C1C=C(/C=C/C(N2CCN(C(C3C=CC(OC)=CC=3)=O)CC2)=O)C=CC=1Br |
| MFCD | N.A. |
| InChi | InChI=1S/C21H21BrN2O3/c1-27-19-9-5-17(6-10-19)21(26)24-14-12-23(13-15-24)20(25)11-4-16-2-7-18(22)8-3-16/h2-11H,12-15H2,1H3/b11-4+ |
| InChiKey | OFHXXBRBGWUOHR-NYYWCZLTSA-N |
| CID | 36295259 |
| Short Description | EBI-2 antagonist |
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