Bulk Inquiry
Fluorescent probe QG-1
Axon 2756
CAS:
2098563-70-1
Purity:
99%
- Soluble in DMSO
- MF: C19H21N3O3
- MW: 339.39
Description
Fluorescent probe QG-1 is a reversible fluorescent sensor for reduced glutathione (GSH) with a reported Kd value of 2.59 mM. It responds rapidly to GSH under physiological conditions, with a reported half-response time of 5.82 seconds.
QG-1 enables real-time monitoring and relative quantification of intracellular GSH dynamics while displaying low cytotoxicity in the reported assay systems. It has been applied in HeLa cells to follow changes in cellular redox buffering and is useful for oxidative-stress, thiol-homeostasis and live-cell imaging studies.
Key Features
- Reversible fluorescent GSH probe
- Kd: 2.59 mM
- Fast response time: t1/2 5.82 seconds
- Low reported cytotoxicity
- Suitable for live-cell measurements
Applications
- Intracellular glutathione imaging
- Redox-homeostasis research
- Oxidative-stress studies
- Live-cell fluorescence assays
- Thiol-dynamics monitoring
More Information
| Parent CAS No. | 2098563-70-1 |
|---|---|
| Chemical Name | (E)-2-Cyano-3-(7-(diethylamino)-2-oxo-2H-chromen-3-yl)-N,N-dimethylacrylamide |
| SMILES | C1C=C2C=C(/C=C(C#N)/C(N(C)C)=O)C(=O)OC2=CC=1N(CC)CC |
| MFCD | N.A. |
| InChi | InChI=1S/C19H21N3O3/c1-5-22(6-2)16-8-7-13-9-14(19(24)25-17(13)11-16)10-15(12-20)18(23)21(3)4/h7-11H,5-6H2,1-4H3/b15-10+ |
| InChiKey | BWLQRALTRQXGBI-XNTDXEJSSA-N |
| CID | 132048523 |
| Short Description | Labeling agent |
Other Categories
Get a Quote for
Loading...