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BAM15
Axon 2736
CAS:
210302-17-3
Purity:
99%
- Soluble in DMSO
- MF: C16H10F2N6O
- MW: 340.29
Description
BAM15 is a mitochondrial protonophore uncoupler, which does not depolarize the plasma membrane. Compared to FCCP, an uncoupler of equal potency, BAM15 treatment of cultured cells stimulates a higher maximum rate of mitochondrial respiration and is less cytotoxic. Furthermore, BAM15 is bioactive in vivo and dose-dependently protects mice from acute renal ischemic-reperfusion injury.
BAM15 reverses diet-induced obesity and insulin resistance in mice.
This product is not intended/sold for (self-)diagnostic and/or therapeutic use.
More Information
| Parent CAS No. | 210302-17-3 |
|---|---|
| Chemical Name | N5,N6-Bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine |
| SMILES | N1=C(NC2C(F)=CC=CC=2)C(NC2C=CC=CC=2F)=NC2=NON=C12 |
| MFCD | MFCD00373912 |
| InChi | InChI=1S/C16H10F2N6O/c17-9-5-1-3-7-11(9)19-13-14(20-12-8-4-2-6-10(12)18)22-16-15(21-13)23-25-24-16/h1-8H,(H,19,21,23)(H,20,22,24) |
| InChiKey | OEGJBRZAJRPPHL-UHFFFAOYSA-N |
| CID | 565708 |
| Short Description | Mitochondrial uncoupler |
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