Bulk Inquiry
Dorzolamide hydrochloride
Axon 1517
- Parent CAS: 120279-96-1
Purity:
99%
- Soluble in water and DMSO
- MF: C10H17ClN2O4S3
- MW: 360.9
Description
Dorzolamide hydrochloride is a carbonic anhydrase inhibitor used to reduce carbonic-anhydrase-dependent bicarbonate formation and aqueous humor production.
Inhibition of carbonic anhydrase in ocular tissues is pharmacologically relevant for lowering intraocular pressure. Dorzolamide is useful as a reference compound in carbonic anhydrase pharmacology, ophthalmic drug research and glaucoma-related experimental systems.
Key Features
- Carbonic anhydrase inhibitor with ophthalmic relevance
- Reduces carbonic-anhydrase-dependent bicarbonate formation
- Supports studies of aqueous humor production and intraocular pressure
- Reference tool for glaucoma and ocular hypertension research
Applications
- Carbonic anhydrase enzyme assays
- Glaucoma and ocular hypertension research
- Ophthalmic pharmacology studies
- Aqueous humor regulation models
More Information
| Parent CAS No. | 120279-96-1 |
|---|---|
| Chemical Name | (4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide 4H-Thieno[2,3-b]thiopyran-2-sulfonamide hydrochloride |
| MFCD | MFCD00884659 |
| Short Description | Carbonic anhydrase inhibitor |
References
- C Plummer et al. Comparison of the effects of topical administration of a fixed combination of dorzolamide-timolol to monotherapy with timolol or dorzolamide on IOP, pupil size, and heart rate in glaucomatous dogs. Vet. Ophthalmol. 2006, 9(4), 245–249.
- S Grover et al. Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa. Am. J. Ophthalmol. 2006, 141(5), 850–858.
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 2662 | CAIX Inhibitor S4 |
From $99.00 |
| 3988 | Brinzolamide |
From $77.00 |
Other Categories
Get a Quote for
Loading...