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Axon 2085
CAS [13258-85-0]
MF C22H30O2MW 326.47
Selective agonist of membrane progesterone receptor (mPR; IC50 value 33.9 nM). Org OD 02-0 mimics the protective effects of progestin hormones on serum starvation-induced cell death and apoptosis in both granulosa and breast cancer cells without altering caspase 3 activity. Org OD 02-0 significantly increased mitochondrial membrane potential (MMP) in serum starved MB468 cells.
KEYWORDS: Org OD 02-0 | supplier | mPR agonist | 19-CH2P4 | OrgOD02-0 | 19-CH2P4 | CAS [13258-85-0] | Progesterone | Progesterone (mPR) | Agonist | Receptors | Progestin | membrane | adipoQ | PAQR
List of publications using Org OD02-0 (Axon 2085) purchased from Axon Medchem
(8S,9S,10S,13S,14S,17S)-17-acetyl-13-methyl-10-vinyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
[13258-85-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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