List of publications using PIK 90 (Axon 1362) purchased from Axon Medchem
(Total 13 publication citations listed; updated in JUNE 2016)
Costales, Abran Q., et al. "Compounds and compositions as protein kinase inhibitors." U.S. Patent No. 8,859,548. 14 Oct. 2014.
2013
Control of Aβ release from human neurons by differentiation status and RET signaling.
D Scholz, Y Chernyshova, M Leist.
Neurobiol. Aging, 2013, 34 (1), 184–199.
http://www.sciencedirect.com/science/article/pii/S0197458012002217
Tumor VEGF: VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
S Chatterjee, LC Heukamp, M Siobal, J Schöttle, C Wieczorek, M Peifer, D Frasca, M Koker, K König, L Meder, D Rauh, R Buettner, J Wolf, RA Brekken, B Neumaier, G Christofori, K Thomas, RT Ullrich.
J. Clin. Invest. published online on Mar 1, 2013. doi:10.1172/JCI65385.
http://www.jci.org/articles/view/65385
HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS.
AM Madera, D Poon, A Smith - U.S. Patent 20,130,096,149, issued April 18, 2013.
(10 drugs from Axon Medchem have been tested)
Read more: http://www.freepatentsonline.com/y2013/0096149.html
Akt and ERK Control the Proliferative Response of Mammary Epithelial Cells to the Growth Factors IGF-1 and EGF Through the Cell Cycle Inhibitor p57Kip2.
DT Worster, T Schmelzle, NL Solimini, ES Lightcap, B Millard, GB Mills, JS Brugge, JG Albeck,
Sci. Signal. 2012, 5(214), ra19 (2012). DOI: 10.1126/scisignal.2001986
http://stke.sciencemag.org/cgi/content/summary/5/214/ra19
Optimal induction of myeloma cell death requires dual blockade of phosphoinositide 3-kinase and mTOR signalling and is determined by translocation subtype.
C Stengel, C W Cheung, J Quinn, K Yong, A Khwaja.
Leukemia 2012, 26(8), 1761-1770. doi:10.1038/leu.2012.69
http://www.ncbi.nlm.nih.gov/pubmed/22415553
Compounds and compositions as protein kinase inhibitors.
AQ Costales, S Huang, JX Jin, Z Liu, S Pecchi, D Poon, J Tellew, and Q Zhang.
U.S. Patent 8,242,260, issued August 14, 2012.
V Serra, M Scaltriti, L Prudkin, PJA Eichhorn, YH Ibrahim, S Chandarlapaty, B Markman, O Rodriguez, M Guzman, S Rodriguez, M Gili, M Russillo, JL Parra, S Singh, J Arribas, N Rosen, J Baselga.
Oncogene 2011, 30, 2547–2557. doi:10.1038/onc.2010.626.
http://www.nature.com/onc/journal/v30/n22/abs/onc2010626a.html
2010
Coordination between Extrinsic Extracellular Matrix Cues and Intrinsic Responses to Orient the Centrosome in Polarizing Cerebellar Granule Neurons.
SK Gupta, KF Meiri, K Mahfooz, U Bharti, and S Mani.
J. Neurosci. 2010, 30(7), 2755-2766. doi: 10.1523/JNEUROSCI.4218-09.2010
http://www.jneurosci.org/content/30/7/2755.short
BacMam-Enabled LanthaScreen® Cellular Assays for PI3K/Akt Pathway Compound Profiling in Disease-Relevant Cell Backgrounds
CB Carlson, MJ Mashock, K Bi.
J. Biomol. Screen, 2010, 15 (3), 327-334. doi: 10.1177/1087057109357788
http://jbx.sagepub.com/content/15/3/327.short
2009
FGF15/FGFR4 Integrates Growth Factor Signaling with Hepatic Bile Acid Metabolism and Insulin Action.
DJ Shin and TF Osborne.
J. Biol. Chem, 2009, 284, 11110-11120. doi: 10.1074/jbc.M808747200
http://www.jbc.org/content/284/17/11110.short
(This is an incomplete list, updated JUNE-2016)
