List of publications using Y 27632 dihydrochloride (Axon 1683) purchased from Axon Medchem
(110 publication citations; this is a partial list from 2021 - May 2024)
2024
Onfray, C., Chevolleau, S., Moinard, E., Girard, O., Mahadik, K., Allsop, R., ... & David, L. (2024). Unraveling hallmark suitability for staging pre-and post-implantation stem cell models. Cell Reports, 43(5), 114232.
* 8 inhibitors, Y27632, CHIR99021, A83-01, SB431542, PD0325901, GO6983, XAV939, and IWR-endo-1, from Axon MedchemHaakonsen, D. L., Heider, M., Ingersoll, A. J., Vodehnal, K., Witus, S. R., Uenaka, T., ... & Rapé, M. (2024). Stress response silencing by an E3 ligase mutated in neurodegeneration. Nature, 626(8000), 874-880.
https://www.nature.com/articles/s41586-023-06985-7
Decoene, I., Nasello, G., Madeiro de Costa, R. F., Nilsson Hall, G., Pastore, A., Van Hoven, I., ... & Papantoniou, I. (2024). Robotics-Driven Manufacturing of Cartilaginous Microtissues for Skeletal Tissue Engineering Applications. Stem Cells Translational Medicine.
Decoene, I., Nasello, G., Madeiro de Costa, R. F., Nilsson Hall, G., Pastore, A., Van Hoven, I., ... & Papantoniou, I. (2024). Robotics-Driven Manufacturing of Cartilaginous Microtissues for Skeletal Tissue Engineering Applications. Stem Cells Translational Medicine.
https://orbi.uliege.be/bitstream/2268/313719/1/decoene.pdf
Verkerke, M., Berdenis van Berlekom, A., Donega, V., Vonk, D., Sluijs, J. A., Butt, N. F., ... & Hol, E. M. (2024). Transcriptomic and morphological maturation of human astrocytes in cerebral organoids. Glia, 72(2), 362-374.
Verkerke, M., Berdenis van Berlekom, A., Donega, V., Vonk, D., Sluijs, J. A., Butt, N. F., ... & Hol, E. M. (2024). Transcriptomic and morphological maturation of human astrocytes in cerebral organoids. Glia, 72(2), 362-374.
https://onlinelibrary.wiley.com/doi/full/10.1002/glia.24479
Luijkx, D. G., Ak, A., Guo, G., van Blitterswijk, C. A., Giselbrecht, S., & Vrij, E. J. (2024). Monochorionic Twinning in Bioengineered Human Embryo Models. Advanced Materials, 2313306.
Luijkx, D. G., Ak, A., Guo, G., van Blitterswijk, C. A., Giselbrecht, S., & Vrij, E. J. (2024). Monochorionic Twinning in Bioengineered Human Embryo Models. Advanced Materials, 2313306.
https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.202313306
Marcó de la Cruz, B., Campos, J., Molinaro, A., Xie, X., Jin, G., Wei, Z., ... & Sterky, F. H. (2024). Liprin-α proteins are master regulators of human presynapse assembly. Nature Neuroscience, 1-14.
Marcó de la Cruz, B., Campos, J., Molinaro, A., Xie, X., Jin, G., Wei, Z., ... & Sterky, F. H. (2024). Liprin-α proteins are master regulators of human presynapse assembly. Nature Neuroscience, 1-14.
https://www.nature.com/articles/s41593-024-01592-9
Tetzlaff, S. K., Reyhan, E., Bengtson, C. P., Schroers, J., Wagner, J., Schubert, M. C., ... & Venkataramani, V. (2024). Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing. bioRxiv, 2024-03.
Tetzlaff, S. K., Reyhan, E., Bengtson, C. P., Schroers, J., Wagner, J., Schubert, M. C., ... & Venkataramani, V. (2024). Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing. bioRxiv, 2024-03.
Campos, J., Molinaro, A., Xie, X., Jin, G., Wei, Z., Acuna, C., & Sterky, F. H. (2024). Liprin-α proteins are master regulators of human presynapse assembly. Nature Neuroscience, 27(4), 629-642.
https://europepmc.org/article/pmc/pmc11001580
Frasson, I., Diamante, L., Zangrossi, M., Carbognin, E., Dalla Pietà, A., Penna, A., ... & Martello, G. (2024). Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern. Journal of Molecular Cell Biology, mjae004.
Frasson, I., Diamante, L., Zangrossi, M., Carbognin, E., Dalla Pietà, A., Penna, A., ... & Martello, G. (2024). Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern. Journal of Molecular Cell Biology, mjae004.
https://academic.oup.com/jmcb/advance-article-abstract/doi/10.1093/jmcb/mjae004/7596546
Pavon, N., Diep, K., Yang, F., Sebastian, R., Martinez-Martin, B., Ranjan, R., ... & Pak, C. (2024). Patterning ganglionic eminences in developing human brain organoids using a morphogen-gradient-inducing device. Cell Reports Methods, 4(1).
Pavon, N., Diep, K., Yang, F., Sebastian, R., Martinez-Martin, B., Ranjan, R., ... & Pak, C. (2024). Patterning ganglionic eminences in developing human brain organoids using a morphogen-gradient-inducing device. Cell Reports Methods, 4(1).
2023
Oldak, B., Wildschutz, E., Bondarenko, V., Comar, M. Y., Zhao, C., Aguilera-Castrejon, A., ... & Hanna, J. H. (2023). Complete human day 14 post-implantation embryo models from naive ES cells. Nature, 622(7983), 562-573.
* Go6983, PD0325901, Y27632, CGP77675, BIRB796, A83-01, CHIR99021, from Axon Medchem
Arboit, M., Zorzan, I., Pellegrini, M., Martini, P., Carbognin, E., & Martello, G. (2023). KLF7 is a general inducer of human pluripotency. bioRxiv, 2023-09.
Arboit, M., Zorzan, I., Pellegrini, M., Martini, P., Carbognin, E., & Martello, G. (2023). KLF7 is a general inducer of human pluripotency. bioRxiv, 2023-09.
* 7i: PD0325901, XAV939, Go6983, Y27632, CHIR99021, A83-01, SB431542 from Axon Medchem
Ferlazzo, G. M., Gambetta, A. M., Amato, S., Cannizzaro, N., Angiolillo, S., Arboit, M., ... & Martello, G. (2023). Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity. Nature Communications, 14(1), 3962.
Ferlazzo, G. M., Gambetta, A. M., Amato, S., Cannizzaro, N., Angiolillo, S., Arboit, M., ... & Martello, G. (2023). Genome-wide screening in pluripotent cells identifies Mtf1 as a suppressor of mutant huntingtin toxicity. Nature Communications, 14(1), 3962.
* CHIR99021, PD0325901, Y27632, SB432542 from Axon Medchem
Onfray, C., Chevolleau, S., Moinard, E., Girard, O., Mahadik, K., Allsop, R. N., ... & David, L. Deciphering Hallmark Combination Distinct for Peri-Implantation Stem Cell Models.
Onfray, C., Chevolleau, S., Moinard, E., Girard, O., Mahadik, K., Allsop, R. N., ... & David, L. Deciphering Hallmark Combination Distinct for Peri-Implantation Stem Cell Models.
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4521994
Hall, G. N., Chandrakar, A., Pastore, A., Ioannidis, K., Moisley, K., Cirstea, M., ... & Papantoniou, I. (2023). Engineering bone-forming biohybrid sheets through the integration of melt electrowritten membranes and cartilaginous microspheroids. Acta Biomaterialia, 165, 111-124.
Hall, G. N., Chandrakar, A., Pastore, A., Ioannidis, K., Moisley, K., Cirstea, M., ... & Papantoniou, I. (2023). Engineering bone-forming biohybrid sheets through the integration of melt electrowritten membranes and cartilaginous microspheroids. Acta Biomaterialia, 165, 111-124.
https://www.sciencedirect.com/science/article/pii/S1742706122006936
Verkerke, M., van Berlekom, A. B., Donega, V., Vonk, D., Sluijs, J. A., Butt, N. F., ... & Hol, E. M. (2023). Transcriptomic and morphological maturation of human astrocytes in. Glial Cells in Alzheimer’s Disease: Insights from Patient-Derived Models, 64.
Verkerke, M., van Berlekom, A. B., Donega, V., Vonk, D., Sluijs, J. A., Butt, N. F., ... & Hol, E. M. (2023). Transcriptomic and morphological maturation of human astrocytes in. Glial Cells in Alzheimer’s Disease: Insights from Patient-Derived Models, 64.
https://onlinelibrary.wiley.com/doi/pdf/10.1002/glia.24479
Loverdou, N., Cuvelier, M., Nilsson Hall, G., Christiaens, A. S., Decoene, I., Bernaerts, K., ... & Papantoniou, I. (2023). Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress. Bioengineering & Translational Medicine, 8(3), e10468.
Loverdou, N., Cuvelier, M., Nilsson Hall, G., Christiaens, A. S., Decoene, I., Bernaerts, K., ... & Papantoniou, I. (2023). Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress. Bioengineering & Translational Medicine, 8(3), e10468.
https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btm2.10468
Carbognin, E., Carlini, V., Panariello, F., Chieregato, M., Guerzoni, E., Benvegnù, D., ... & Martello, G. (2023). Esrrb guides naive pluripotent cells through the formative transcriptional programme. Nature cell biology, 25(5), 643-657.
Carbognin, E., Carlini, V., Panariello, F., Chieregato, M., Guerzoni, E., Benvegnù, D., ... & Martello, G. (2023). Esrrb guides naive pluripotent cells through the formative transcriptional programme. Nature cell biology, 25(5), 643-657.
* Y27632, XAV939 from Axon Medchem
Guo, M. G., Reynolds, D. L., Ang, C. E., Liu, Y., Zhao, Y., Donohue, L. K., ... & Khavari, P. A. (2023). Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases. Nature Genetics, 55(11), 1876-1891.
Guo, M. G., Reynolds, D. L., Ang, C. E., Liu, Y., Zhao, Y., Donohue, L. K., ... & Khavari, P. A. (2023). Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases. Nature Genetics, 55(11), 1876-1891.
https://www.nature.com/articles/s41588-023-01533-5
Sebastian, R., Jin, K., Pavon, N., Bansal, R., Potter, A., Song, Y., ... & Pak, C. (2023). Schizophrenia-associated NRXN1 deletions induce developmental-timing-and cell-type-specific vulnerabilities in human brain organoids. Nature Communications, 14(1), 3770.
Sebastian, R., Jin, K., Pavon, N., Bansal, R., Potter, A., Song, Y., ... & Pak, C. (2023). Schizophrenia-associated NRXN1 deletions induce developmental-timing-and cell-type-specific vulnerabilities in human brain organoids. Nature Communications, 14(1), 3770.
https://www.nature.com/articles/s41467-023-39420-6
Moya-Jódar, M., Ullate-Agote, A., Barlabé, P., Rodríguez-Madoz, J. R., Abizanda, G., Barreda, C., ... & Aranguren, X. L. (2023). Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures. Stem Cell Reports, 18(1), 64-80.
Moya-Jódar, M., Ullate-Agote, A., Barlabé, P., Rodríguez-Madoz, J. R., Abizanda, G., Barreda, C., ... & Aranguren, X. L. (2023). Revealing cell populations catching the early stages of human embryo development in naive pluripotent stem cell cultures. Stem Cell Reports, 18(1), 64-80.
https://www.cell.com/stem-cell-reports/pdf/S2213-6711(22)00548-3.pdf
Khalil, K. (2023). Creating new opportunities for cardiac transplantation after circulatory death (DCD) using a novel pharmacological agent.
Khalil, K. (2023). Creating new opportunities for cardiac transplantation after circulatory death (DCD) using a novel pharmacological agent.
https://papyrus.bib.umontreal.ca/xmlui/handle/1866/32158
Zorzan, I., Carbognin, E., Lauria, A., Proserpio, V., Benvegnu, D., Dalrio, C., ... & Martello, G. (2023). TGF-beta dynamically controls epithelial identity in a 3D model of human epiblast. bioRxiv, 2023-12.
Zorzan, I., Carbognin, E., Lauria, A., Proserpio, V., Benvegnu, D., Dalrio, C., ... & Martello, G. (2023). TGF-beta dynamically controls epithelial identity in a 3D model of human epiblast. bioRxiv, 2023-12.
https://www.biorxiv.org/content/10.1101/2023.12.07.570575v1.full
Zorzan, I., Betto, R. M., Rossignoli, G., Arboit, M., Drusin, A., Corridori, C., ... & Martello, G. (2023). Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation. EMBO reports, e55235.
Zorzan, I., Betto, R. M., Rossignoli, G., Arboit, M., Drusin, A., Corridori, C., ... & Martello, G. (2023). Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation. EMBO reports, e55235.
* 7i: PD0325901, XAV939, Go6983, Y27632, CHIR99021, A83-01, SB431542 from Axon Medchem
Etxaniz Díaz de Durana, J. (2023). A Comparative Study Of Cell Culture Conditions During Conversion From Primed To Naive Human Pluripotent Stem Cells.
* 6i: PD0325901, CHIR99021, Y27632, Go6983, SP600125, BIRB796, from Axon Medchem
Frasson, I., Diamante, L., Zangrossi, M., Carbognin, E., Pietà, A. D., Penna, A., ... & Martello, G. (2023). Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern. bioRxiv, 2023-01.
Decoene, I., Nasello, G., Madeiro, R. F., Nilsson Hall, G., Pastore, A., Van Hoven, I., ... & Papantoniou, I. (2023). Robotics-driven manufacturing of cartilaginous microtissues for the bio-assembly of skeletal implants. bioRxiv, 2023-01.
Chenouard, V., Leray, I., Tesson, L., Remy, S., Allan, A., Archer, D., ... & Anegon, I. (2023). Excess of Guide RNA Reduces Knockin Efficiency And Drastically Increases On-Target Large Deletions. iScience.
2022
Romayor, I., Herrera, L., Burón, M., Martin-Inaraja, M., Prieto, L., Etxaniz, J., ... & Eguizabal, C. (2022). A Comparative Study of Cell Culture Conditions during Conversion from Primed to Naive Human Pluripotent Stem Cells. Biomedicines, 10(6), 1358.
* 6i: CHIR99021, PD0325901, SP600125, BIR796, Y27632, GO6983 from Axon Medchem
Zorzan, I., Betto, R. M., Rossignoli, G., Arboit, M., Drusin, A., Martini, P., & Martello, G. (2022). Chemical conversion of human conventional Pluripotent Stem Cells to Trophoblast Stem Cells. bioRxiv, 2022-04.
* 7i: PD0325901, XAV939, Go6983, Y27632, CHIR99021, A83-01, SB431542 from Axon Medchem
Viukov, S., Shani, T., Bayerl, J., Sheban, D., Stelzer, Y., Novershtern, N., & Hanna, J. H. (2022). Human primed and naïve PSCs are both competent in differentiating into bona fide trophoblast stem cells. BioRxiv, 2022-05.
* 7i: PD0325901, XAV939, Go6983, Y27632, CHIR99021, A83-01, CGP77675 from Axon Medchem
Berdenis van Berlekom, A., Kübler, R., Hoogeboom, J. W., Vonk, D., Sluijs, J. A., Pasterkamp, R. J., ... & Boks, M. P. (2022). Exposure to the Amino Acids Histidine, Lysine, and Threonine Reduces mTOR Activity and Affects Neurodevelopment in a Human Cerebral Organoid Model. Nutrients, 14(10), 2175.
Tarazi, S., Aguilera-Castrejon, A., Joubran, C., Ghanem, N., Ashouokhi, S., Roncato, F., ... & Hanna, J. H. (2022). Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell, 185(18), 3290-3306.
* CHIR99021, PD0325901, Y27632, from Axon Medchem
Peischard, S., Möller, M., Disse, P., Ho, H. T., Verkerk, A. O., Strutz-Seebohm, N., ... & Seebohm, G. (2022). Virus-induced inhibition of cardiac pacemaker channel HCN4 triggers bradycardia in human-induced stem cell system. Cellular and Molecular Life Sciences, 79(8), 440.
* CHIR99021 and Y27632 from Axon Medchem
Loverdou, N., Cuvelier, M., Nilsson Hall, G., Christiaens, A. S., Decoene, I., Bernaerts, K., ... & Papantoniou, I. (2022). Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress. Bioengineering & Translational Medicine, e10468.
Vas, W. J., Shah, M., Roberts, H. C., & Roberts, S. J. (2022). Decellularised cartilage ECM culture coatings drive rapid and robust chondrogenic differentiation of human periosteal cells. Bioengineering, 9(5), 203.
McSweeney, D., Gabriel, R., Jin, K., Pang, Z. P., Aronow, B., & Pak, C. (2022). CASK loss of function differentially regulates neuronal maturation and synaptic function in human induced cortical excitatory neurons. Iscience, 25(10), 105187.
Hall, G. N., Chandrakar, A., Pastore, A., Ioannidis, K., Moisley, K., Cirstea, M., ... & Papantoniou, I. (2022). Engineering bone-forming biohybrid sheets through the integration of melt electrowritten membranes and cartilaginous microspheroids. Acta Biomaterialia.
Coll, M., Ariño, S., Martínez‐Sánchez, C., Garcia‐Pras, E., Gallego, J., Moles, A., ... & Sancho‐Bru, P. (2022). Ductular reaction promotes intrahepatic angiogenesis through Slit2–Roundabout 1 signaling. Hepatology, 75(2), 353-368.
* A8301, CHIR99021, Frskolin and Y27632 from Axon Medchem
Christiaens, A. S., Decoene, I., Bernaerts, K., & Papantoniou, I. (2022). Stirred culture of cartilaginous microtissues promotes chondrogenic hypertrophy through exposure to intermittent shear stress.
Sheban, D., Shani, T., Maor, R., Aguilera-Castrejon, A., Mor, N., Oldak, B., ... & Merbl, Y. (2022). SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity. Molecular cell, 82(1), 106-122.
* CHIR99021, PD0325901 and Y27632 from Axon Medchem
Decoene, I., Herpelinck, T., Geris, L., Luyten, F., & Papantoniou, I. (2022). Engineering bone-forming callus organoid implants in a xenogeneic-free differentiation medium. Frontiers in Chemical Engineering, 4(892190).
Loopmans, S., Stockmans, I., Carmeliet, G., & Stegen, S. (2022). Isolation and in vitro characterization of murine young-adult long bone skeletal progenitors. Frontiers in Endocrinology, 13, 930358.
Chu, S., Moujaber, O., Lemay, S., & Stochaj, U. (2022). Multiple pathways promote microtubule stabilization in senescent intestinal epithelial cells. npj Aging, 8(1), 16.
Viukov, S., Shani, T., Bayerl, J., Aguilera-Castrejon, A., Oldak, B., Sheban, D., ... & Novershtern, N. (2022). Human primed and naïve PSCs are both able to differentiate into trophoblast stem cells. Stem cell reports, 17(11), 2484-2500.
* 7i: PD0325901, XAV939, Go6983, Y27632, CHIR99021, CGP77675, PD173074 from Axon Medchem
Dekel, C., Morey, R., Hanna, J., Laurent, L. C., Ben-Yosef, D., & Amir, H. (2022). Stabilization of hESCs in two distinct substates along the continuum of pluripotency. Iscience, 25(12), 105469.
* CHIR99021, PD0325901, BIRB796, CGP77675 and Y27632 from Axon Medchem
Gildin, L., Rauti, R., Vardi, O., Kuznitsov-Yanovsky, L., Maoz, B. M., Segal, M., & Ben-Yosef, D. (2022). Impaired functional connectivity underlies fragile x syndrome. International Journal of Molecular Sciences, 23(4), 2048.
Chaves-Pérez, A., Santos-de-Frutos, K., de la Rosa, S., Herranz-Montoya, I., Perna, C., & Djouder, N. (2022). Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation. Journal of Experimental Medicine, 219(11), e20212405.
Moya-Jódar, M., Ullate-Agote, A., Barlabé, P., Rodríguez-Madoz, J. R., Abizanda, G., Barreda, C., ... & Aranguren, X. L. (2022). Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells. bioRxiv, 2022-03.
https://www.biorxiv.org/content/10.1101/2022.03.06.482812.abstract
https://www.biorxiv.org/content/10.1101/2022.03.06.482812.abstract
* PD0325901 and Y27632 from Axon Medchem
Al Hosni, R., Bozec, L., Roberts, S. J., & Cheema, U. (2022). Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension. Iscience, 25(4), 104059.
Flippe, L., Gaignerie, A., Sérazin, C., Baron, O., Saulquin, X., Anegon, I., ... & Guillonneau, C. (2022). Generation of CD34+ CD43+ hematopoietic progenitors to induce thymocytes from human pluripotent stem cells. Cells, 11(24), 4046.
Locatelli, M., Delhaes, F., Cherpin, O., Black, M. E., Carnesecchi, S., Preynat-Seauve, O., ... & Krause, K. H. (2022). Optimization of Thymidine Kinase-Based Safety Switch for Neural Cell Therapy. Cells, 11(3), 502.
Tournaire, G., Loopmans, S., Stegen, S., Rinaldi, G., Eelen, G., Torrekens, S., ... & Carmeliet, G. (2022). Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle. Cell reports, 40(4), 111105.
Kobayashi, M., Kobayashi, M., Kreuzer, J., Zaniewski, E., Kim, J. J., Shioda, K., ... & Shioda, T. (2022). Viral proteins and virus-like particles of the LTR5_Hs endogenous retrovirus in human primordial germ cell-like cells. bioRxiv, 2022-09.
Sebastian, R., Jin, K., Pavon, N., Bansal, R., Potter, A., Song, Y., ... & Pak, C. (2022). Single cell transcriptomic profiling of human brain organoids reveals developmental timing-and cell-type-specific vulnerabilities induced by NRXN1 CNVs in schizophrenia. bioRxiv, 2022-08.
Dantas, M., Oliveira, A., Aguiar, P., Maiato, H., & Ferreira, J. G. (2022). Nuclear tension controls mitotic entry by regulating cyclin B1 nuclear translocation. Journal of Cell Biology, 221(12), e202205051.
McSweeney, D., Gabriel, R., Jin, K., Pang, Z. P., Aronow, B., & Pak, C. (2022). Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons. bioRxiv, 2022-02.
Moermansa, G. C., van Gastela, N., Ageing, K. U., & Carmeliet, G. NESTIN-GFP TRANSGENE LABELS SKELETAL PROGENITORS IN THE PERIOSTEUM 7.
Mazid, M. A., Ward, C., Luo, Z., Liu, C., Li, Y., Lai, Y., ... & Esteban, M. A. (2022). Rolling back human pluripotent stem cells to an eight-cell embryo-like stage. Nature, 605(7909), 315-324.
2021Hall, G. N., Rutten, I., Lammertyn, J., Eberhardt, J., Geris, L., Luyten, F. P., & Papantoniou, I. (2021). Cartilaginous spheroid-assembly design considerations for endochondral ossification: towards robotic-driven biomanufacturing. Biofabrication, 13(4), 045025.
Tong, Z., Kwak, E., Aguiar, A., Peng, B., Pouton, C. W., Voelcker, N. H., & Haynes, J. M. (2021). Compartmentalized microfluidic chambers enable long-term maintenance and communication between human pluripotent stem cell-derived forebrain and midbrain neurons. Lab on a Chip, 21(20), 4016-4030.
* Y27632, LDN193189 and SB431652 from Axon Medchem
Preisler, L., Habib, A., Shapira, G., Kuznitsov-Yanovsky, L., Mayshar, Y., Carmel-Gross, I., ... & Ben-Yosef, D. (2021). Heterozygous APC germline mutations impart predisposition to colorectal cancer. Scientific reports, 11(1), 1-12.
*Y27632 and LDN193189 from Axon Medchem
Bayerl, J., Ayyash, M., Shani, T., Manor, Y. S., Gafni, O., Massarwa, R., ... & Hanna, J. H. (2021). Principles of signaling pathway modulation for enhancing human naive pluripotency induction. Cell Stem Cell. 28(9), 1549-1565.
* Y27632 and 14 other inhibitors from Axon Medchem, including CHIR99021, PD0325901, IWR1, BIRB0796, Go6983, CGP77675, RIN1, LDN193189, A8301, SB590885, BIX02189, RU-SKI43, BIX02194, XAV939
Eenjes, E., Buscop-van Kempen, M., Boerema-de Munck, A., Edel, G. G., Benthem, F., de Kreij-de Bruin, L., ... & Rottier, R. J. (2021). SOX21 modulates SOX2-initiated differentiation of epithelial cells in the extrapulmonary airways. Elife, 10, e57325.
*Y27632 and DAPT from Axon Medchem
Van Beylen, K., Papantoniou, I., & Aerts, J. M. (2021). Microcarrier screening and evaluation for dynamic expansion of human periosteum-derived progenitor cells in a xenogeneic free medium. Frontiers in Bioengineering and Biotechnology, 9, 414.
Hall, G. N., Tam, W. L., Andrikopoulos, K. S., Casas-Fraile, L., Voyiatzis, G. A., Geris, L., ... & Papantoniou, I. (2021). Patterned, organoid-based cartilaginous implants exhibit zone specific functionality forming osteochondral-like tissues in vivo. Biomaterials, 273, 120820.
van Dijk, F., Song, S., van Eck, G. W. A., Wu, X., Bos, I. S. T., Boom, D. H. A., ... & Melgert, B. N. (2021). Inhalable textile microplastic fibers impair airway epithelial growth. Biorxiv, 2021-01.
Guo, M. G. (2021). Decoding Transcription Regulatory Patterns in Health and Disease. Stanford University.
2020
Lito, S., Sidibe, A., Ilmjarv, S., Burda, P., Baumgartner, M., Wehrle-Haller, B., ... & Marteyn, A. (2020). Induced Pluripotent Stem Cells to Understand Mucopolysaccharidosis. I: Demonstration of a Migration Defect in Neural Precursors. Cells, 9(12), 2593.
Zorzan, I., Pellegrini, M., Arboit, M., Incarnato, D., Maldotti, M., Forcato, M., ... & Martello, G. (2020). The transcriptional regulator ZNF398 mediates pluripotency and epithelial character downstream of TGF-beta in human PSCs. Nature communications, 11(1), 1-16.
* Y27632, A83-01, Sb431542 and LDN193189 from Axon Medchem
Stegen, S., Rinaldi, G., Loopmans, S., Stockmans, I., Moermans, K., Thienpont, B., ... & Carmeliet, G. (2020). Glutamine metabolism controls chondrocyte identity and function. Developmental Cell, 53(5), 530-544.
Bayerl, J., Ayyash, M., Shani, T., Manor, Y., Gafni, O., Kalma, Y., ... & Hanna, J. H. (2020). Tripartite inhibition of SRC-WNT-PKC signalling consolidates human naïve pluripotency. bioRxiv.
* Y27632 and 10 other inhibitors from Axon Medchem
Castel, G., Meistermann, D., Bretin, B., Firmin, J., Justine, B. L. I. N., Loubersac, S., ... & David, L. (2020). Generation of human induced trophoblast stem cells. bioRxiv.
*Y27632 and other 4 inhibitors, CHIR99021, PD0325901, GO6983 and PD173074 from Axon Medchem
Castel, G., Meistermann, D., Bretin, B., Firmin, J., Blin, J., Loubersac, S., ... & David, L. (2020). Induction of human trophoblast stem cells from somatic cells and pluripotent stem cells. Cell Reports, 33(8), 108419.
* Y27632 and 8 other inhibitors from Axon Medchem
Tournaire, G., Stegen, S., Giacomini, G., Stockmans, I., Moermans, K., Carmeliet, G., & van Gastel, N. (2020). Nestin-GFP transgene labels skeletal progenitors in the periosteum. Bone, 133, 115259.
Groeneveldt, L. C., Herpelinck, T., Maréchal, M., Politis, C., van IJcken, W. F., Huylebroeck, D., ... & Luyten, F. P. (2020). The bone-forming properties of periosteum-derived cells differ between harvest sites. Frontiers in cell and developmental biology, 8.
Teijeira, A., Garasa, S., Gato, M., Alfaro, C., Migueliz, I., Cirella, A., ... & Melero, I. (2020). CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity. Immunity, 52(5), 856-871.
Nilsson Hall, G., Mendes, L. F., Gklava, C., Geris, L., Luyten, F. P., & Papantoniou, I. (2020). Developmentally engineered callus organoid bioassemblies exhibit predictive in vivo long bone healing. Advanced Science, 7(2), 1902295.
van Gastel, N., Stegen, S., Eelen, G., Schoors, S., Carlier, A., Daniëls, V. W., ... & Carmeliet, G. (2020). Lipid availability determines fate of skeletal progenitor cells via SOX9. Nature, 579(7797), 111-117.
2019
Stiers, P. J., Stegen, S., van Gastel, N., Van Looveren, R., Torrekens, S., & Carmeliet, G. (2019). Inhibition of the Oxygen Sensor PHD2 Enhances Tissue‐Engineered Endochondral Bone Formation. Journal of Bone and Mineral Research, 34(2), 333-348.
Gupta, P., Hall, G. N., Geris, L., Luyten, F. P., & Papantoniou, I. (2019). Human Platelet Lysate Improves Bone Forming Potential of Human Progenitor Cells Expanded in Microcarrier‐Based Dynamic Culture. Stem cells translational medicine, 8(8), 810-821.
Potirat, P., Wattanapanitch, M., Viprakasit, V., Kheolamai, P., & Issaragrisil, S. (2019). An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling. Stem cell research, 34, 101344.
Preisler, L., Ben‐Yosef, D., & Mayshar, Y. (2019). Adenomatous Polyposis Coli as a Major Regulator of Human Embryonic Stem Cells Self‐Renewal. Stem Cells, 37(12), 1505-1515.
Di Stefano, B., Luo, E. C., Haggerty, C., Aigner, S., Charlton, J., Brumbaugh, J., ... & Hochedlinger, K. (2019). The RNA helicase DDX6 controls cellular plasticity by modulating P-body homeostasis. Cell stem cell, 25(5), 622-638.
* Y27632 and 6 other inhibitors from Axon Medchem
Giulitti, S., Pellegrini, M., Zorzan, I., Martini, P., Gagliano, O., Mutarelli, M., ... & Martello, G. (2019). Direct generation of human naive induced pluripotent stem cells from somatic cells in microfluidics. Nature cell biology, 21(2), 275-286.
Frank, S., Ahuja, G., Bartsch, D., Russ, N., Yao, W., Kuo, J. C. C., ... & Kurian, L. (2019). yylncT defines a class of divergently transcribed lncRNAs and safeguards the T-mediated mesodermal commitment of human PSCs. Cell stem cell, 24(2), 318-327.
*Y27632 and CHIR99021 from Axon Medchem
Elvassore, N., Martello, G., Giulitti, S., Pellegrini, M., & Gagliano, O. (2019). Human Fibroblast Reprogramming to Naïve Induced Pluripotent Stem Cells in Microfluidics.
*Y27632 and CHIR99021 from Axon Medchem
2018
* Y-27632, PD0325901, Gö6983, IM-12, SB590885, WH-4-023 and CHIR99021 from Axon Medchem
Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., ... & Hanna, J.H. (2018). Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. Cell stem cell. in press
* CHIR99021, PD0325901, GO6983, CGP77675, Y27632, DBZ are all from Axon Medchem
Potirat, P., Wattanapanitch, M., Kheolamai, P., & Issaragrisil, S. (2018). Establishment of a human iPSC line (MUSIi007-A) from peripheral blood of normal individual using Sendai viral vectors. Stem Cell Research.
Sahakyan, A., Clement, K., Clowers, K. J., Erickson, A. R., Shioda, K., Gygi, S. P., ... & Plath, K. Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells. Nature Methods. 2018, 15, 732–740.
* Y27632, IM-12, SB590885, WH4-023, CHIR99021, PD0325901 and GO6983 from Axon Medchem.
Gupta, P., Geris, L., Luyten, F. P., & Papantoniou, I. (2018). An Integrated Bioprocess for the Expansion and Chondrogenic Priming of Human Periosteum‐Derived Progenitor Cells in Suspension Bioreactors. Biotechnology journal, 13(2), 1700087.
Hosokawa, Y., Toyoda, T., Fukui, K., Baden, M. Y., Funato, M., Kondo, Y., ... & Watanabe, A. (2018). Insulin‐producing cells derived from ‘induced pluripotent stem cells’ of patients with fulminant type 1 diabetes: Vulnerability to cytokine insults and increased expression of apoptosis‐related genes. Journal of diabetes investigation, 9(3), 481-493.
* CHIR99021 and Y-27632 from Axon Medchem
Vas, W. J., Shah, M., Blacker, T. S., Duchen, M. R., Sibbons, P., & Roberts, S. J. (2018). Decellularized Cartilage Directs Chondrogenic Differentiation: Creation of a Fracture Callus Mimetic. Tissue Engineering Part A.
2017
Hopkinson, B. M., Klitgaard, M. C., Petersen, O. W., Villadsen, R., Rønnov-Jessen, L., & Kim, J. (2017). Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype. Oncotarget, 8(6), 10580.
* Y27632 and SB431542 from Axon Medchem
Stolarczyk, M., Veit, G., Schnur, A., Veltman, M., Lukacs, G. L., & Scholte, B. J. (2017). Extracellular oxidation in cystic fibrosis airway epithelium causes enhanced EGFR/ADAM17 activity. American Journal of Physiology-Lung Cellular and Molecular Physiology, 314(4), L555-L568.
Rademacher, S., Verheijen, B. M., Hensel, N., Peters, M., Bora, G., Brandes, G., ... & van der Pol, W. L. (2017). Metalloprotease-mediated cleavage of PlexinD1 and its sequestration to actin rods in the motoneuron disease spinal muscular atrophy (SMA). Human molecular genetics, 26(20), 3946-3959.
* Y27632 and SB431542 from Axon Medchem
Rademacher, S. (2017). Cytoskeletal dysregulation in the motoneuron disease Spinal Muscular Atrophy (SMA) (Doctoral dissertation, Tierärztliche Hochschule Hannover).
* Y27632 and SB431542 from Axon Medchem
2016
Morsing, M., Klitgaard, M. C., Jafari, A., Villadsen, R., Kassem, M., Petersen, O. W., & Rønnov-Jessen, L. (2016). Evidence of two distinct functionally specialized fibroblast lineages in breast stroma. Breast Cancer Research, 18(1), 108.
Lambrechts, T., Papantoniou, I., Rice, B., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2016). Large-scale progenitor cell expansion for multiple donors in a monitored hollow fibre bioreactor. Cytotherapy, 18(9), 1219-1233.
Lambrechts, T., Papantoniou, I., Viazzi, S., Bovy, T., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2016). Evaluation of a monitored multiplate bioreactor for large-scale expansion of human periosteum derived stem cells for bone tissue engineering applications. Biochemical engineering journal, 108, 58-68.
Frank, P., & Jean-Marie, A. Large-scale progenitor cell expansion for multiple donors in a monitored hollow fibre bioreactor.
Tieng, V., Cherpin, O., Gutzwiller, E., Zambon, A. C., Delgado, C., Salmon, P., ... & Krause, K. H. (2016). Elimination of proliferating cells from CNS grafts using a Ki67 promoter-driven thymidine kinase. Molecular Therapy-Methods & Clinical Development, 3, 16069
Harschnitz, O., van den Berg, L. H., Johansen, L. E., Jansen, M. D., Kling, S., Vieira de Sá, R., ... & Pasterkamp, R. J. (2016). Autoantibody pathogenicity in a multifocal motor neuropathy induced pluripotent stem cell–derived model. Annals of neurology.
*Y27632 and SB431542 from Axon Medchem
Pathak, J. L., Verschueren, P., Lems, W. F., Bravenboer, N., Klein-Nulend, J., Bakker, A. D., & Luyten, F. P. (2016). Serum of patients with active rheumatoid arthritis inhibits differentiation of osteochondrogenic precursor cells. Connective tissue research, 57(3), 226-235.
2015
Kirkeby, A., Nelander, J., & Parmar, M. (2015). Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Developing stem cell-based therapies for neural repair.
*SB431542 and Y27632 from Axon Medchem
Lambrechts, T., Papantoniou, I., Viazzi, S., Bovy, T., Schrooten, J., Luyten, F. P., & Aerts, J. M. (2015). Evaluation of a monitored multiplate bioreactor for large-scale expansion of human periosteum derived stem cells for bone tissue engineering applications. Biochemical Engineering Journal.
2014
Hartley, B. J., Fabb, S. A., Finnin, B. A., Haynes, J. M., & Pouton, C. W. (2014). Zinc-finger nuclease enhanced gene targeting in human embryonic stem cells. JoVE (Journal of Visualized Experiments), (90), e51764-e51764.
de Esch, Celine EF, Mehrnaz Ghazvini, Friedemann Loos, Nune Schelling-Kazaryan, W. Widagdo, Shashini T. Munshi, Erik van der Wal et al. "Stem Cell Reports." Epigenetic Characterization of the FMR1 Promoter in Induced Pluripotent Stem Cells from Human Fibroblasts Carrying an Unmethylated Full Mutation.
* CHIR99021, PD0325901, SB203580, Y27632 were procured from Axon Medchem.
2013
Gafni, O., Weinberger, L., Mansour, A. A., Manor, Y. S., Chomsky, E., Ben-Yosef, D., ... & Hanna, J.H. (2013). Derivation of novel human ground state naive pluripotent stem cells. Nature, 504(7479), 282-286. (Cited by 292 until 6/6/16)
*CHIR99021, PD0325901, SB202190, BIRB796, Y27632 from Axon Medchem
