GPR52

GPR52

G-protein-coupled receptor 52 (GPR52) is an orphan Gs-coupled G-protein-coupled receptor. GPR52 inhibits dopamine D2 receptor signaling and activates dopamine D1/N-methyl-d-aspartate receptors via intracellular cAMP accumulation, and therefore, GPR52 agonists may have potential as a novel class of antipsychotics.

Read More
sort-descending
  • FTBMT
    2962
    FTBMT
    The price depends on the options chosen on the product page

    From $137.50

  • GPR52 Comp-43
    3522
    GPR52 Comp-43
    The price depends on the options chosen on the product page

    From $99.00

2 Items

More About GPR52

G-protein-coupled receptor 52 (GPR52) is an orphan Gs-coupled G-protein-coupled receptor. GPR52 inhibits dopamine D2 receptor signaling and activates dopamine D1/N-methyl-d-aspartate receptors via intracellular cAMP accumulation, and therefore, GPR52 agonists may have potential as a novel class of antipsychotics.[1]

[1] M. Setoh et al. Discovery of the first potent and orally available agonist of the orphan G-protein-coupled receptor 52. J Med Chem. 2014 Jun 26;57(12):5226-37.

Loading...