SRA
Fenfluramines and norfenfluramines are 5-HT transporter substrates and potent 5-HT releasers. Other 5-HT releasing agents include m-chlorophenylpiperazine (mCPP), a major metabolite of the antidepressant drug trazodone. Findings from in vitro and in vivo studies support the hypothesis that fenfluramines and mCPP release neuronal 5-HT via a non-exocytotic carrier-mediated exchange mechanism involving 5-HT transporters.[1]
[1] R.B. Rothman and M.H. Baumann. Serotonin releasing agents. Neurochemical, therapeutic and adverse effects. Pharmacol Biochem Behav. 2002 Apr;71(4):825-36.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2850 | Fenfluramine hydrochloride | 5-HT releasing agent | €75.00 | |