Antiviral agents
Antiviral agents are a class of drugs for treatment of viral infections. Among the human viruses or the diseases they produce for which we need useful or improved drugs or vaccines, we may list the following: HIV-1 (AIDS), cytomegalovirus, Epstein-Barr virus, HSV- 1, HSV-2, varicella virus, influenza A, influenza B, enterovirus, hepatitis A, hepatitis B, adenovirus, common cold, bronchiolitis, croup, dengue, poliomyelitis, measles, rabies, warts, chickenpox, mumps, and rubella[1].
[1] WH Prusoff et al. Approaches to antiviral drug development. Yale J Biol Med. 1989 Mar-Apr; 62(2): 215–225.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3382 | Zidovudine | NRT inhibitor | €50.00 | |
| 2469 | YK 4-279 | Inhibitor of ETV1, ERG and interactions of EWS-FLI1 and RNA helicase A | €95.00 | |
| 3506 | Vidarabine | Inhibitor of herpes virus DNA polymerase | €50.00 | |
| 3585 | Vesatolimod | Potent, selective and orally available TLR7 agonist | €80.00 | |
| 3173 | Velpatasvir | Hepatitis C virus NS5A inhibitor | €50.00 | |
| 3491 | Stavudine | NRT inhibitor | €60.00 | |
| 2200 | SRPIN 340 | Selective ATP-competitive inhibitor of SRPK kinase activity | €95.00 | |
| 3301 | Sofosbuvir | Potent and selective HCV NS5B polymerase inhibitor | €90.00 | |
| 3573 | Ribavirin | Antiviral agent; Suppressor of eIF4E activity | €60.00 | |
| 3110 | Remdesivir | Potent and selective inhibitor of Ebola virus (EBOV); Broad-spectrum antiviral agent | €90.00 | |
| 3120 | Raltegravir | Potent, selective and orally bioavailable HIV integrase inhibitor | €90.00 | |
| 3385 | Penciclovir | Highly selective inhibitor of herpes virus DNA polymerase | €60.00 | |
| 3136 | Oseltamivir phosphate | Selective and orally available inhibitor of influenza virus neuraminidases | €50.00 | |
| 2077 | OG-L002 hydrochloride | Inhibitor of lysine specific demethylase 1 (LSD1 aka KDM1A) | €125.00 | |
| 2907 | Nucleozin | Influenza A nucleoprotein targeting molecule | €95.00 | |
| 3588 | NGI-1 | Potent and cell-permeable inhibitor of oligosaccharyltransferase | €90.00 | |
| 3483 | NBD-556 | HIV-1 entry inhibitor; gp120-CD4 interaction blocker | €70.00 | |
| 2081 | ML 324 dihydrochloride | Inhibitor of JMJD2 histone demethylase | €90.00 | |
| 3562 | ML 324 | Inhibitor of JMJD2 histone demethylase | €90.00 | |
| 3188 | MK-4482 | Potent and orally bioavailable broad-spectrum antiviral agent | €95.00 | |
| 3304 | Lamivudine | Potent NRT inhibitor | €60.00 | |
| 2597 | KPT 335 | XPO1 inhibitor; selective inhibitor of nuclear export (SINE) | €95.00 | |
| 3432 | K22 | Inhibitor of membrane-bound coronaviral RNA synthesis | €110.00 | |
| 3241 | Ganciclovir | Inhibitor of CMV and herpes virus DNA polymerase | €60.00 | |
| 3135 | Favipiravir | Potent and selective inhibitor of viral RNA polymerase | €70.00 | |
| 3141 | DHQZ 36 | Potent retrograde trafficking inhibitor | €120.00 | |
| 1815 | Delavirdine | NNRT inhibitor (HIV-1) | €90.00 | |
| 1669 | Danoprevir | HCV NS3/4A serine protease inhibitor | €90.00 | |
| 2093 | Daclatasvir dihydrochloride | Hepatitis C virus (HCV) NS5A protein inhibitor | €70.00 | |
| 2455 | CU-T12-9 | Selective TLR1/TLR2 agonist that facilitates the TLR1/2 complex formation | €120.00 | |