Antiviral agents
Antiviral agents are a class of drugs for treatment of viral infections. Among the human viruses or the diseases they produce for which we need useful or improved drugs or vaccines, we may list the following: HIV-1 (AIDS), cytomegalovirus, Epstein-Barr virus, HSV- 1, HSV-2, varicella virus, influenza A, influenza B, enterovirus, hepatitis A, hepatitis B, adenovirus, common cold, bronchiolitis, croup, dengue, poliomyelitis, measles, rabies, warts, chickenpox, mumps, and rubella[1].
[1] WH Prusoff et al. Approaches to antiviral drug development. Yale J Biol Med. 1989 Mar-Apr; 62(2): 215–225.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3384 | Acyclovir | Highly selective inhibitor of herpes virus DNA polymerase | €60.00 | |
| 1571 | AG 7088 | HRV3C protease inhibitor | €60.00 | |
| 3465 | Amenamevir | Potent helicase-primase inhibitor | €130.00 | |
| 3140 | Arbidol hydrochloride | Broad-spectrum antiviral agent | €60.00 | |
| 2266 | BAY 57-1293 | Potent helicase-primase inhibitor, effective against herpes simplex virus (HSV) infections | €80.00 | |
| 1441 | BMS 232632 | Protease inhibitor | €80.00 | |
| 3360 | CBS1117 | Virus entry inhibitor | €110.00 | |
| 2093 | Daclatasvir dihydrochloride | Hepatitis C virus (HCV) NS5A protein inhibitor | €70.00 | |
| 1669 | Danoprevir | HCV NS3/4A serine protease inhibitor | €90.00 | |
| 1815 | Delavirdine | NNRT inhibitor (HIV-1) | €90.00 | |
| 3141 | DHQZ 36 | Potent retrograde trafficking inhibitor | €120.00 | |
| 3135 | Favipiravir | Potent and selective inhibitor of viral RNA polymerase | €70.00 | |
| 3241 | Ganciclovir | Inhibitor of CMV and herpes virus DNA polymerase | €60.00 | |
| 3432 | K22 | Inhibitor of membrane-bound coronaviral RNA synthesis | €110.00 | |
| 2597 | KPT 335 | XPO1 inhibitor; selective inhibitor of nuclear export (SINE) | €95.00 | |
| 3304 | Lamivudine | Potent NRT inhibitor | €60.00 | |
| 3188 | MK-4482 | Potent and orally bioavailable broad-spectrum antiviral agent | €95.00 | |
| 3562 | ML 324 | Inhibitor of JMJD2 histone demethylase | €90.00 | |
| 2081 | ML 324 dihydrochloride | Inhibitor of JMJD2 histone demethylase | €90.00 | |
| 3483 | NBD-556 | HIV-1 entry inhibitor; gp120-CD4 interaction blocker | €70.00 | |
| 3588 | NGI-1 | Potent and cell-permeable inhibitor of oligosaccharyltransferase | €90.00 | |
| 2907 | Nucleozin | Influenza A nucleoprotein targeting molecule | €95.00 | |
| 2077 | OG-L002 hydrochloride | Inhibitor of lysine specific demethylase 1 (LSD1 aka KDM1A) | €125.00 | |
| 3136 | Oseltamivir phosphate | Selective and orally available inhibitor of influenza virus neuraminidases | €50.00 | |
| 3385 | Penciclovir | Highly selective inhibitor of herpes virus DNA polymerase | €60.00 | |
| 3120 | Raltegravir | Potent, selective and orally bioavailable HIV integrase inhibitor | €90.00 | |
| 3110 | Remdesivir | Potent and selective inhibitor of Ebola virus (EBOV); Broad-spectrum antiviral agent | €90.00 | |
| 3573 | Ribavirin | Antiviral agent; Suppressor of eIF4E activity | €60.00 | |
| 3301 | Sofosbuvir | Potent and selective HCV NS5B polymerase inhibitor | €90.00 | |
| 2200 | SRPIN 340 | Selective ATP-competitive inhibitor of SRPK kinase activity | €95.00 | |