Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
3245 6-Mercaptopurine Purine analog; Immunosuppressant €50.00
1028 6-Methoxy-N-propyl-2-aminotetraline hydrochloride Building Block; unknown pharmacology Inquire
3253 6-Thioguanine Purine analog; Immunosuppressant €40.00
2089 7,8-Dihydroxyflavone Tyrosine kinase receptor B (TrkB) agonist €55.00
1012 7-Hydroxy-DPAT hydrobromide D3 agonist €60.00
1054 7-Methoxy-2-aminotetralin hydrochloride Building Block; unknown pharmacology Inquire
1029 7-Methoxy-N-propyl-2-aminotetraline hydrochloride Building Block; unknown pharmacology Inquire
1015 8-Hydroxy-DPAT hydrobromide 5-HT1A agonist €60.00
1057 8-Methoxy-2-aminotetralin hydrochloride Building Block; 5-HT1A agonist Inquire
1032 8-Methoxy-N-propyl-2-aminotetraline hydrochloride Building Block; unknown pharmacology Inquire
1909 A 1070722 Selective inhibitor of GSK-3 €95.00
1666 A 357300 hydrochloride MetAP2 inhibitor €90.00
2944 A 381393 Potent, brain-penetrant, selective antagonist of the dopamine D4 receptor €125.00
1831 A 66 PI3K inhibitor (p110-α specific) €95.00
1466 A 769662 AMPK activator €85.00
1744 A 77-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €80.00
1698 A 770041 Orally active src-family selective lck inhibitor €140.00
1816 A 784168 TRPV1 receptor antagonist €95.00
1915 A 803467 Blocker of the voltage-gated Nav1.8 channel €95.00
2182 A 804598 Potent and selective P2X7 antagonist €125.00
1421 A 83-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €70.00
2155 A 841720 Non-competitive mGluR1 antagonist €85.00
2059 A 922500 Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor €105.00
1990 A 943931 H4 antagonist €70.00
2705 A-196 Potent and selective inhibitor of SUV4-20 €105.00
2720 A-92 Inhibitor of GCN2 (EIF2AK4) €145.00
1179 A1B1 hydrochloride CCR1 antagonist €125.00
3019 A2764 dihydrochloride Selective inhibitor of the TRESK potassium channel €105.00
3060 A2793 Inhibitor of the TRESK and TASK-1 potassium channel €95.00
3416 AA147 Endoplasmic reticulum (ER) proteostasis regulator €80.00

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