Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
3553 (S)-Trolox Vitamin E analog; Antioxidant €40.00
3435 (S)-VU0637120 First-in-class, selective neuropeptide Y4 receptor allosteric antagonist €120.00
1341 (S)-WAY 100135 dihydrochloride 5-HT1A antagonist €95.00
2221 (Z)-Endoxifen The more active (Z)-isomer of Endoxifen (SERM; Axon 2190) €150.00
2718 (±)-Blebbistatin Potent and specific inhibitor of class II myosins €95.00
1308 (±)-BMS 204352 Potassium channel opener; racemate of Axon 1112 Inquire
3488 (±)-CGP-12177A β1/β2 adrenoceptor antagonist, β3 adrenoceptor agonist €120.00
1687 (±)-E-Homocamptothecin Potent topoisomerase I (Topo 1) inhibitor €120.00
1076 (±)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €95.00
1224 (±)-LY 367385 mGluR1a antagonist €80.00
1093 (±)-LY 426965 dihydrochloride 5-HT1A antagonist €115.00
1106 (±)-MDL 105725 5-HT2A antagonist €145.00
1072 (±)-PD 128907 hydrochloride D3 agonist €95.00
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
1070 (±)-PHNO hydrochloride D2 agonist; racemate of PHNO (Axon 1071) Inquire
1176 1,1,1-Trifluoro-3-(5-fluoro-2-methoxy-phenyl)-3-methyl-butan-2-one Building block for Glucocorticoid ligand Inquire
2537 1,5-Isoquinolinediol PARP1 inhibitor and neuroprotective agent €50.00
3088 1-BCP Brain-penetrant modulator of AMPA receptor €75.00
2434 1-Deazaadenosine Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro €140.00
1313 1-EBIO K+ channel opener (Ca2+ activated) €50.00
2603 1-Nitrosocyclohexyl acetate HNO donor Inquire
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
2222 10058-F4 c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase €80.00
2989 15-LOX-1 inhibitor i472 Inhibitor of 15-lipoxygenase-1 (15-LOX-1) €165.00
3617 1R,3R-RSL3 (negative control) Negative control of 1S,3R-RSL3 as GPX4 inhibitor €90.00
3611 1S,3R-RSL3 GPX4 inhibitor; Ferroptosis inducer €90.00
2496 2,5-Dimethylcelecoxib Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity €75.00
1878 2-Aminoacridone Labeling agent of malondialdehyde (Fluorescent) €95.00
1190 2-Chloroadenosine Adenosine A1 and A2A agonist €65.00
3565 2-FPBA First potent, reversible and slow-onset inhibitor of mandelate racemase (MR) €50.00

Items 61 to 90 of 2368 total

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