Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1739 (RS)-3,5-DHPG mGluR1 and mGluR5 agonist (rac. Axon 1740) €80.00
1740 (S)-3,5-DHPG mGluR1 and mGluR5 agonist €80.00
1224 (±)-LY 367385 mGluR1a antagonist €80.00
3088 1-BCP Brain-penetrant modulator of AMPA receptor €75.00
2155 A 841720 Non-competitive mGluR1 antagonist €85.00
2732 ADX71743 Negative allosteric modulator (NAM) of mGluR7 €105.00
3415 AMPA Highly selective AMPA receptor agonist €110.00
1747 AZ 12216052 Positive allosteric modulator (PAM) of mGluR8 €105.00
3335 AZD6765 dihydrochloride Noncompetitive NMDA antagonist €90.00
1644 Biphenyl-indanone A Positive allosteric modulator (PAM) of mGluR2 €85.00
1217 CFM 2 AMPA antagonist €115.00
2691 CHPG mGluR5 agonist €95.00
3333 Cinnabarinic acid mGluR4 agonist €80.00
2079 CMPDA Positive allosteric modulator of AMPA receptor €85.00
1200 CNQX AMPA/Kainate antagonist €85.00
2522 CNQX disodium salt AMPA/Kainate antagonist €90.00
2254 CP 101606 NMDA NR2B antagonist €120.00
1406 CP 101606 mesylate NMDA NR2B antagonist €85.00
1431 CPPHA Positive allosteric modulator (PAM) of mGluR5 €95.00
1972 CTEP Negative allosteric modulator (NAM) of mGluR5 €120.00
3089 CX516 Positive allosteric modulator of AMPA receptor €70.00
3090 CX546 Positive allosteric modulator of AMPA receptor €95.00
1259 Desmethyl YM 298198 hydrochloride mGluR1 antagonist €105.00
1201 DNQX AMPA/Kainate antagonist €50.00
1246 Eliprodil NMDA antagonist €90.00
2687 Farampator Second-generation ampakine that potentiates AMPA receptor function €99.00
1345 Fenobam mGluR5 antagonist €66.00
1262 Gavestinel NMDA antagonist (glycine site) €110.00
1374 GYKI 53655 AMPA antagonist €85.00
1156 Ifenprodil L-(+)-tartrate NMDA antagonist €55.00

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