Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3777 | (R)-AS-1 | First-in-class highly selective and orally bioavailable PAM of EAAT2 | €145.00 | |
| 1739 | (RS)-3,5-DHPG | mGluR1 and mGluR5 agonist (rac. Axon 1740) | €90.00 | |
| 1740 | (S)-3,5-DHPG | mGluR1 and mGluR5 agonist | €90.00 | |
| 1224 | (±)-LY 367385 | mGluR1a antagonist | €80.00 | |
| 3088 | 1-BCP | Brain-penetrant modulator of AMPA receptor | €75.00 | |
| 2155 | A 841720 | Non-competitive mGluR1 antagonist | €85.00 | |
| 2732 | ADX71743 | Negative allosteric modulator (NAM) of mGluR7 | €110.00 | |
| 3415 | AMPA | Highly selective AMPA receptor agonist | €110.00 | |
| 1747 | AZ 12216052 | Positive allosteric modulator (PAM) of mGluR8 | €110.00 | |
| 3335 | AZD6765 dihydrochloride | Noncompetitive NMDA antagonist | €90.00 | |
| 1644 | Biphenyl-indanone A | Positive allosteric modulator (PAM) of mGluR2 | €95.00 | |
| 1217 | CFM 2 | AMPA antagonist | €115.00 | |
| 2691 | CHPG | mGluR5 agonist | €95.00 | |
| 3333 | Cinnabarinic acid | mGluR4 agonist | €90.00 | |
| 4169 | CIQ | First NMDA NR2C/NR2D PAM | €130.00 | |
| 2079 | CMPDA | Positive allosteric modulator of AMPA receptor | €85.00 | |
| 1200 | CNQX | AMPA/Kainate antagonist | €85.00 | |
| 2522 | CNQX disodium salt | AMPA/Kainate antagonist | €90.00 | |
| 2254 | CP 101606 | NMDA NR2B antagonist | €120.00 | |
| 1406 | CP 101606 mesylate | NMDA NR2B antagonist | €85.00 | |
| 1431 | CPPHA | Positive allosteric modulator (PAM) of mGluR5 | €95.00 | |
| 1972 | CTEP | Negative allosteric modulator (NAM) of mGluR5 | €120.00 | |
| 3089 | CX516 | Positive allosteric modulator of AMPA receptor | €70.00 | |
| 3090 | CX546 | Positive allosteric modulator of AMPA receptor | €95.00 | |
| 1259 | Desmethyl YM 298198 hydrochloride | mGluR1 antagonist | €140.00 | |
| 3841 | Dextromethorphan hydrobromide | Noncompetitive NMDA receptor antagonist | €60.00 | |
| 1201 | DNQX | AMPA/Kainate antagonist | €50.00 | |
| 1246 | Eliprodil | NMDA antagonist | €90.00 | |
| 2687 | Farampator | Second-generation ampakine that potentiates AMPA receptor function | €99.00 | |
| 1345 | Fenobam | mGluR5 antagonist | €70.00 | |