Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 4093 | (Z)-4-Hydroxytamoxifen | The more active metabolite of Tamoxifen (SERM; Axon 3252) | €110.00 | |
| 2221 | (Z)-Endoxifen | The more active (Z)-isomer of Endoxifen (SERM; Axon 2190) | €150.00 | |
| 2051 | Bazedoxifene acetate | Selective estrogen receptor modulator (SERM) | €80.00 | |
| 1748 | Bazedoxifene hydrochloride | Selective estrogen receptor modulator (SERM) | €70.00 | |
| 2790 | BHPI | ER-α antagonist | €125.00 | |
| 3844 | CITFA | Selective GPER agonist | €110.00 | |
| 3650 | Clomiphene citrate | Selective estrogen receptor modulator (SERM) | €50.00 | |
| 3320 | Diethylstilbestrol | Estrogen receptor agonist | €50.00 | |
| 1232 | DPN | Estrogen (ER-β) agonist | €70.00 | |
| 3118 | DS45500853 | ERRα agonist | €120.00 | |
| 4095 | Elacestrant dihydrochloride | Orally bioavailable selective estrogen receptor degrader (SERD) | €220.00 | |
| 2190 | Endoxifen | Selective estrogen receptor modulator (SERM) | €125.00 | |
| 2707 | Endoxifen hydrochloride | Selective estrogen receptor modulator (SERM) | €130.00 | |
| 1898 | ERB 041 | Selective estrogen receptor β (ERβ) agonist | €95.00 | |
| 1926 | Estetrol | Estrogen receptor agonist (four- to five-fold preference for the Erα) | €130.00 | |
| 4275 | Fulvestrant | Potent estrogen receptor antagonist; Antiestrogen | €80.00 | |
| 4306 | Palazestrant | Orally bioavailable complete ER antagonist and selective ER degrader | €160.00 | |
| 1231 | PPT | ER-α agonist | €95.00 | |
| 3250 | Raloxifene | Selective estrogen receptor modulator (SERM) | €50.00 | |
| 4184 | SLU-PP-332 | Pan ERRα/β/γ agonist | €90.00 | |
| 2967 | SR 19881 | Potent dual agonist of ERRβ/γ | €135.00 | |
| 3252 | Tamoxifen | Selective estrogen receptor modulator (SERM) | €50.00 | |
| 2697 | WAY-200070 | Brain penetrant ERβ-selective agonist | €105.00 | |
| 2337 | XCT 790 | ERRα inverse agonist and potent mitochondrial uncoupler | €120.00 | |
| 2652 | ZB716 | Steroidal, orally bioavailable SERD | €130.00 | |
| 4212 | α-Estradiol | Endogenous estrogen receptor ligand | €90.00 | |