Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1687 | (±)-E-Homocamptothecin | Potent topoisomerase I (Topo 1) inhibitor | €120.00 | |
| 2537 | 1,5-Isoquinolinediol | PARP1 inhibitor and neuroprotective agent | €50.00 | |
| 2222 | 10058-F4 | c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase | €80.00 | |
| 1496 | 3-Aminobenzamide | Competitive small molecule inhibitor of PARP | €40.00 | |
| 1902 | 4μ8C | IRE1α inhibitor | €105.00 | |
| 3419 | 5-Bromo-2’-deoxyuridine | Thymidine analog; Labeling agent of cell proliferation | €50.00 | |
| 3384 | Acyclovir | Highly selective inhibitor of herpes virus DNA polymerase | €60.00 | |
| 1529 | AG 014699 | PARP1 inhibitor | €60.00 | |
| 4276 | AG14361 | Potent PARP1 inhibitor | €130.00 | |
| 3834 | Alantolactone | STAT3 inhibitor; NLRP3 inhibitor | €90.00 | |
| 3465 | Amenamevir | Potent helicase-primase inhibitor | €120.00 | |
| 3008 | AOH1160 | First-in-class, potent and orally available PCNA inhibitor | €120.00 | |
| 4030 | AOH1996 | Orally available PCNA inhibitor | €140.00 | |
| 2137 | APE1 Inhibitor III | Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) | €110.00 | |
| 2136 | AR03 | Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) | €105.00 | |
| 3140 | Arbidol hydrochloride | Broad-spectrum antiviral agent | €60.00 | |
| 3220 | ARN24139 | Orally active topoisomerase II poison | €130.00 | |
| 4264 | ART-446 | Potent CHK2 inhibitor | Inquire | |
| 1992 | AS 1517499 | Potent and selective STAT6 inhibitor | €130.00 | |
| 2839 | AS 1842856 | Inhibitor of the Forkhead box protein O1 (FOXO1) | €95.00 | |
| 4140 | AZD0156 | Selective and orally active ATM inhibitor | €90.00 | |
| 2241 | AZD2461 | PARP inhibitor with poor P-glycoprotein substrate qualities | €95.00 | |
| 3800 | AZD4573 | Inhibitor of CDK9 | Inquire | |
| 4068 | AZD7648 | DNA-PK inhibitor | €90.00 | |
| 1399 | AZD7762 hydrochloride | CHK inhibitor | €60.00 | |
| 2042 | Azithromycin | Macrolide antibiotic; Binds the 50S ribosomal subunit | €50.00 | |
| 3935 | BAY-1251152 | Potent and highly selective CDK9/P-TEFb inhibitor | Inquire | |
| 3108 | BC-LI-0186 | Specific inhibitor of the LRS-RagD interaction | €90.00 | |
| 3760 | Belzutifan | Second-generation potent, selective and orally active HIF-2α inhibitor | €280.00 | |
| 4028 | BI-87G3 | Highly potent covalent NPAS3 heterodimer inhibitor | €120.00 | |