Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1687 (±)-E-Homocamptothecin Potent topoisomerase I (Topo 1) inhibitor €120.00
2537 1,5-Isoquinolinediol PARP1 inhibitor and neuroprotective agent €50.00
2222 10058-F4 c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase €80.00
1496 3-Aminobenzamide Competitive small molecule inhibitor of PARP €40.00
1902 4μ8C IRE1α inhibitor €105.00
3419 5-Bromo-2’-deoxyuridine Thymidine analog; Labeling agent of cell proliferation €50.00
3384 Acyclovir Highly selective inhibitor of herpes virus DNA polymerase €60.00
1529 AG 014699 PARP1 inhibitor €60.00
3834 Alantolactone STAT3 inhibitor; NLRP3 inhibitor €90.00
3465 Amenamevir Potent helicase-primase inhibitor €130.00
3008 AOH1160 First-in-class, potent and orally available PCNA inhibitor €120.00
4030 AOH1996 Orally available PCNA inhibitor €140.00
2137 APE1 Inhibitor III Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) €110.00
2136 AR03 Inhibitor of apurinic/apyrimidinic endonuclease 1 (APE1) €105.00
3140 Arbidol hydrochloride Broad-spectrum antiviral agent €60.00
3220 ARN24139 Orally active topoisomerase II poison €130.00
1992 AS 1517499 Potent and selective STAT6 inhibitor €130.00
2839 AS 1842856 Inhibitor of the Forkhead box protein O1 (FOXO1) €95.00
4140 AZD0156 Selective and orally active ATM inhibitor Inquire
2241 AZD2461 PARP inhibitor with poor P-glycoprotein substrate qualities €95.00
3800 AZD4573 Inhibitor of CDK9 Inquire
4068 AZD7648 DNA-PK inhibitor Inquire
1399 AZD7762 hydrochloride CHK inhibitor €60.00
2042 Azithromycin Macrolide antibiotic; Binds the 50S ribosomal subunit €50.00
3935 BAY-1251152 Potent and highly selective CDK9/P-TEFb inhibitor Inquire
3108 BC-LI-0186 Specific inhibitor of the LRS-RagD interaction €90.00
3760 Belzutifan Second-generation potent, selective and orally active HIF-2α inhibitor €280.00
4028 BI-87G3 Highly potent covalent NPAS3 heterodimer inhibitor €120.00
2301 BIBR 1532 Potent and selective telomerase inhibitor inducing senescence in human cancer cells. €70.00
2462 BMH 21 Inhibitor of RNA Polymerase I (RNAP1) €95.00

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