Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2356 | BMS 833923 | Oral antagonist of the Hedgehog signaling component Smoothened (SMO) | €75.00 | |
| 1500 | GDC 0449 | Hedgehog (Hh) pathway inhibitor | €70.00 | |
| 2196 | LY 2940680 | Small-molecule antagonist of the Smoothened (SMO) receptor | €120.00 | |
| 1938 | MRT 10 | Smoothened (SMO) receptor antagonist | €125.00 | |
| 1619 | NVP-LDE225 | Smoothened (SMO) antagonist | €85.00 | |
| 2027 | PF 5274857 hydrochloride | Smoothened (SMO) antagonist | €95.00 | |
| 1690 | Purmorphamine | Hedgehog signaling pathway activator | €120.00 | |
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