Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1539 | AT 7519 mesylate | CDK inhibitor | €80.00 | |
| 1966 | AZD5438 | CDK inhibitor (1, 2, and 9 specific) | €80.00 | |
| 3228 | CDK inhibitor CR8 | Potent CDK inhibitor (1, 2, 5, 7, and 9 specific) | €130.00 | |
| 1776 | Dinaciclib | CDK inhibitor (1, 2, 5, and 9 specific) | €90.00 | |
| 2273 | LEE 011 | Orally bioavailable and highly selective small-molecule inhibitor of CDK4/6 | €80.00 | |
| 1494 | MK 1775 | Wee1 kinase inhibitor | €80.00 | |
| 2695 | NSC 23005 sodium | Novel small molecule inhibitor of INK4C (p18(INK4C) or p18) | €90.00 | |
| 1243 | NSC 625987 | CDK4 inhibitor | €95.00 | |
| 2052 | Palbociclib isethionate | Orally active cyclin-dependent kinase (CDK4/6) inhibitor | €125.00 | |
| 1505 | PD0332991 hydrochloride | CDK4 and CDK6 inhibitor | €85.00 | |
| 3693 | PF-06873600 | CDK inhibitor (4, 6, and 8 specific) | Inquire | |
| 1983 | R 547 | CDK inhibitor (1, 2, and 4 specific) | €95.00 | |
| 1530 | RO 3306 | CDK1 inhibitor | €80.00 | |
| 1614 | SNS 032 | CDK inhibitor (2, 7 and 9 specific) | €85.00 | |
| 3184 | SR-4835 | Potent, highly selective and orally bioavailable dual CDK12/CDK13 inhibitor | €130.00 | |
| 1765 | TG 003 | Inhibitor of Cdc2-like kinase (Clk) family | €110.00 | |
| 3560 | THZ1 | Covalent CDK7 inhibitor | €60.00 | |
| 3561 | THZ1 dihydrochloride | Covalent CDK7 inhibitor | €110.00 | |
| 3402 | THZ531 | First-in-class, potent, selective, covalent CDK12/CDK13 inhibitor | €130.00 | |
| 3535 | XY028-140 | Potent and selective CDK4/6 inhibitor; PROTAC | €120.00 | |