Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2717 | Apigenin | Selective inhibitor of Casein kinase 2 (CK2) | €70.00 | |
| 2757 | Asciminib | Potent and selective allosteric BCR-ABL1 inhibitor | €120.00 | |
| 3771 | AZD2858 | Potent and highly selective Glycogen Synthase Kinase-3β inhibitor | €95.00 | |
| 3936 | Bisindolylmaleimide I | Potent and selective PKC inhibitor | €120.00 | |
| 3939 | Bisindolylmaleimide IV | Potent PKC inhibitor | €120.00 | |
| 3853 | BMS-599626 | Potent and selective EGFR and ErbB2 inhibitor | Inquire | |
| 3509 | Cromolyn disodium | GSK-3β inhibitor | €50.00 | |
| 4056 | DYRK1A inhibitor compound 11 | Highly selective and ligand-efficient Dyrk1A inhibitor | €150.00 | |
| 4329 | Etimizol | CK2 ligand; Cognitive enhancer; Nootropic drug | Recently added | €130.00 |
| 3848 | Fasudil hydrochloride | Orally active ROCK inhibitor; Ca2+ channel antagonist | €50.00 | |
| 4158 | GRL018-21 | Potent, highly selective and non-covalent GRK5 inhibitor | €180.00 | |
| 4311 | GSK-3β inhibitor 12 | GSK-3β inhibitor | Recently added | €90.00 |
| 3780 | LMTK3 inhibitor C28 | Potent LMTK3 inhibitor | €120.00 | |
| 3851 | LXS-196 | Potent and selective protein kinase C inhibitor | Inquire | |
| 3843 | LYN-1604 dihydrochloride | Potent ULK1 agonist | €130.00 | |
| 4177 | MR-2088 | Best-in-class, potent and selective ULK1/2 inhibitor | Recently added | €160.00 |
| 3986 | N-Desmethyltamoxifen hydrochloride | Metabolite of Tamoxifen (Axon 3252); PKC inhibitor | €180.00 | |
| 3961 | PF-03758309 | Potent and ATP-competitive inhibitor of p21-activated kinase (PAK4) | Inquire | |
| 3676 | PKN3 inhibitor compound 16 | Potent, cell-active protein kinase novel 3 (PKN3) inhibitor | €130.00 | |
| 3866 | TAE226 | Potent and ATP-competitive dual FAK and IGF-1R inhibitor | €110.00 | |
| 4272 | TAS2940 | Orally active, brain-penetrable, and irreversible pan-ERBB inhibitor | €110.00 | |
| 4242 | UNC-CA2-103 | Potent, narrow spectrum, sub-family selective TLK2 inhibitor | €130.00 | |
| 3789 | YH-306 | FAK inhibitor | €90.00 | |