Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3750 | GSK3326595 | Orally active, potent, selective, SAM uncompetitive, peptide competitive, slow binding inhibitor of protein arginine methyltransferase 5 (PRMT5) | Inquire | |
| 3919 | GSK3368715 hydrochloride | A first-in-class, orally active, potent and selective, SAM-Noncompetive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs) | Inquire | |
| 3754 | JNJ-64619178 dihydrochloride | SAM-pocket binding (SAM Competitive) PRMT5 inhibitor | Inquire | |
| 3796 | MRTX1719 hydrochloride | Inhibitor of the PRMT5.MTA complex | Inquire | |
| 3798 | PF-06855800 | SAM-pocket-binding (SAM competitive) PRMT5 inhibitor | Inquire | |
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