Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
Axon ID | Name | Description | From price | |
---|---|---|---|---|
1229 | (R)-(-)-Rolipram | PDE4 inhibitor | €110.00 | |
2830 | (R)-CE3F4 | Potent inhibitor of EPAC1 | €120.00 | |
1432 | (S)-(+)-Rolipram | PDE4 inhibitor | €115.00 | |
1957 | Apremilast | PDE4 inhibitor | €60.00 | |
1178 | BAY 19-8004 | PDE4 inhibitor | €160.00 | |
3148 | BPN14770 | Potent, selective, allosteric inhibitor of PDE4D | €120.00 | |
3574 | Carbazeran | Potent phosphodiesterase inhibitor and an aldehyde oxidase (AO) substrate | €90.00 | |
2929 | CE3F4 | Inhibitor of EPAC1 | €95.00 | |
3169 | Crisaborole | Potent PDE4 inhibitor; Anti-inflammatory agent | €60.00 | |
2847 | ESI-08 | Selective EPAC antagonist | €140.00 | |
3326 | HJC0197 | Potent EPAC antagonist | €90.00 | |
2730 | HJC0350 | Highly potent and selective EPAC2 antagonist | €95.00 | |
1127 | L 454560 | PDE4 inhibitor | Inquire | |
3314 | Milrinone | PDE3 inhibitor | €80.00 | |
1168 | Olprinone hydrochloride | PDE3 inhibitor | €119.00 | |
1482 | Parogrelil | PDE3 inhibitor | €120.00 | |
3179 | Pentoxifylline | Non-specific inhibitor of cAMP phosphodiesterases | €50.00 | |
4013 | Piclamilast | Potent and selective PDE4 inhibitor | €130.00 | |
2352 | Roflumilast | First specific PDE4 inhibitor licensed for treatment of COPD | €90.00 | |
1212 | Rolipram | PDE4 inhibitor | €65.00 | |
4002 | RS 25344 | Selective PDE4 inhibitor | €130.00 | |
1592 | SB 207499 | PDE4 inhibitor | €70.00 | |
1225 | U 73122 | PLC inhibitor | €95.00 | |
3889 | Vinpocetine | Brain-penetrant PDE/IKK inhibitor; Na+ channel blocker | €50.00 | |
1216 | Zardaverine | PDE3 and PDE4 inhibitor | €80.00 |