Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

25 Item(s)

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Axon ID Name Description From price
1229 (R)-(-)-Rolipram PDE4 inhibitor €110.00
2830 (R)-CE3F4 Potent inhibitor of EPAC1 €120.00
1432 (S)-(+)-Rolipram PDE4 inhibitor €115.00
1957 Apremilast PDE4 inhibitor €60.00
1178 BAY 19-8004 PDE4 inhibitor €160.00
3148 BPN14770 Potent, selective, allosteric inhibitor of PDE4D €120.00
3574 Carbazeran Potent phosphodiesterase inhibitor and an aldehyde oxidase (AO) substrate €90.00
2929 CE3F4 Inhibitor of EPAC1 €95.00
3169 Crisaborole Potent PDE4 inhibitor; Anti-inflammatory agent €60.00
2847 ESI-08 Selective EPAC antagonist €140.00
3326 HJC0197 Potent EPAC antagonist €90.00
2730 HJC0350 Highly potent and selective EPAC2 antagonist €95.00
1127 L 454560 PDE4 inhibitor Inquire
3314 Milrinone PDE3 inhibitor €80.00
1168 Olprinone hydrochloride PDE3 inhibitor €119.00
1482 Parogrelil PDE3 inhibitor €120.00
3179 Pentoxifylline Non-specific inhibitor of cAMP phosphodiesterases €50.00
4013 Piclamilast Potent and selective PDE4 inhibitor €130.00
2352 Roflumilast First specific PDE4 inhibitor licensed for treatment of COPD €90.00
1212 Rolipram PDE4 inhibitor €65.00
4002 RS 25344 Selective PDE4 inhibitor €130.00
1592 SB 207499 PDE4 inhibitor €70.00
1225 U 73122 PLC inhibitor €95.00
3889 Vinpocetine Brain-penetrant PDE/IKK inhibitor; Na+ channel blocker €50.00
1216 Zardaverine PDE3 and PDE4 inhibitor €80.00

25 Item(s)

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