Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1758 | (R)-(+)-BAY K 8644 | Calcium (Ca2+) channel modulator | €115.00 | |
| 1759 | (S)-(-)-BAY K 8644 | Calcium (Ca2+) channel activator (L-type voltage-gated) | €115.00 | |
| 3631 | ABR-238901 | Potent S100A8/A9 blocker | €170.00 | |
| 3785 | ABT-639 | Peripherally acting, selective and orally bioavailable T-type Ca2+ channel blocker | Recently added | €115.00 |
| 3026 | AC1903 | Selective TRPC5 inhibitor | €95.00 | |
| 3015 | Amlodipine besylate | Ca2+ channel blocker | €90.00 | |
| 3013 | Aranidipine | Ca2+ channel antagonist | €110.00 | |
| 3160 | Azelnidipine | Calcium channel blocker | €70.00 | |
| 3014 | Barnidipine hydrochloride | Potent Ca2+ channel blocker (L-type voltage gated) | €105.00 | |
| 1697 | BAY K 8644 | Calcium (Ca2+) channel activator (L-type voltage-gated) | €95.00 | |
| 3131 | Benidipine hydrochloride | Ca2+ channel blocker | €70.00 | |
| 3036 | BI 749327 | Potent, selective and orally bioavailable TRPC6 inhibitor | €160.00 | |
| 1818 | Calhex 231 hydrochloride | NAM of the extracellular CaSR | €99.00 | |
| 1732 | CaSR antagonist 18c | Calcium-sensing receptor (CaSR) antagonist | €130.00 | |
| 1252 | CGS 9343B | Calmodulin inhibitor | €90.00 | |
| 2458 | Clemizole | Inhibitor of the transient receptor potential channel TRPC5 | €75.00 | |
| 1868 | CRAC inhibitor 44 | Potent and selective CRAC ion channel blocker | €110.00 | |
| 3323 | Diltiazem hydrochloride | Ca2+ channel antagonist (L-type voltage gated) | €50.00 | |
| 2952 | Fantofarone | Highly potent and specific Ca2+ channel antagonist | €125.00 | |
| 1448 | Felodipine | Ca2+ channel blocker | €65.00 | |
| 3501 | Isradipine | Ca2+ channel antagonist | €60.00 | |
| 3185 | L651582 | Ca2+ channel blocker | €120.00 | |
| 3254 | Nicardipine | Ca2+ channel antagonist | €50.00 | |
| 2068 | Nifedipine | Ca2+ channel blocker (L-type voltage gated) | €55.00 | |
| 3158 | Otilonium bromide | Ca2+ channel blocker | €70.00 | |
| 1274 | PNU 37883 hydrochloride | K+ channel blocker (ATP sensitive, vascular) | €85.00 | |
| 1823 | Pregabalin | Reduces synaptic signaling by binding to α2δ subunits | €85.00 | |
| 3644 | Propafenone hydrochloride | Ca2+/K+/Na+ channel blocker; Antiarrhythmic agent | €60.00 | |
| 1221 | SKF 96365 hydrochloride | Ca2+ channel blocker | €105.00 | |
| 3452 | Verapamil hydrochloride | Ca2+ channel antagonist | €50.00 | |