Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1125 | BACE-1 Inhibitor | BACE 1 inhibitor | €110.00 | |
| 2957 | BACE-2 Inhibitor | Potent and highly selective BACE 2 inhibitor | €140.00 | |
| 2117 | Begacestat | Selective γ-secretase inhibitor (GSI) | €85.00 | |
| 2158 | Boc-D-FMK | Broad spectrum caspase inhibitor | €110.00 | |
| 1484 | DAPT | γ-Secretase inhibitor | €90.00 | |
| 1375 | Ivachtin | Caspase-3 inhibitor | €55.00 | |
| 3744 | KEA1-97 | Thioredoxin-caspase 3 interaction disruptor | €90.00 | |
| 2869 | LX2343 | BACE 1 inhibitor | €125.00 | |
| 2225 | LY 2811376 | The first orally available non-peptidic BACE 1 inhibitor | €125.00 | |
| 1964 | LY 2886721 hydrochloride | BACE 1 inhibitor | €105.00 | |
| 1743 | PAC 1 | Procaspase activating compound 1 | €80.00 | |
| 3746 | PTI-125 dihydrochloride | Orally available molecule targeting filamin A (FLNA) | €120.00 | |
| 2521 | RO 4929097 | Potent γ-secretase inhibitor (GSI) targeting Notch signaling in various tumor cells | €135.00 | |
| 4166 | Verubecestat | First-in-class, potent, orally bioavailable high-affinity BACE1 inhibitor | €80.00 | |
| 3857 | VX-765 | Caspase-1 inhibitor | Inquire | |
| 2159 | Z-VAD-FMK | Pan-caspase inhibitor with in vivo activity | Inquire | |
| 1487 | γ-Secretase Inhibitor BZ | γ-Secretase inhibitor (GSI) | €90.00 | |
| 1488 | γ-Secretase Inhibitor DBZ | γ-Secretase inhibitor (GSI) | €80.00 | |
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