Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 4229 | 2',5'-Dideoxyadenosine | P-Site inhibitor of adenylate cyclase | Recently added | €90.00 |
| 3575 | AMG510 | Highly potent, selective, and orally bioavailable KRAS-G12C inhibitor | €90.00 | |
| 3084 | ARS-1620 | Potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor | €145.00 | |
| 2172 | BAY 58-2667 hydrochloride | Soluble, potent nitric oxide-independent guanylyl cyclase (sGC) activator | €125.00 | |
| 3053 | BAY-293 | Potent, selective and cell-active inhibitor of KRAS-SOS1 interaction | €140.00 | |
| 3471 | BI-3406 | Inhibitor of KRAS/Son of Sevenless 1 (SOS1) interaction | Inquire | |
| 2397 | BQU 57 | Inhibitor of the RAS-like small GTPases RalA and RalB | €125.00 | |
| 2184 | CID 1067700 | First inhibitor of Rab7 GTPase | €125.00 | |
| 2829 | Fendiline hydrochloride | KRAS inhibitor; Ca2+ channel blocker (L-type voltage gated) | €50.00 | |
| 2264 | Forskolin | Activator of adenylate cyclase. Naturally occurring labdane diterpene | €90.00 | |
| 3768 | GDC-6036 | Inhibitor of KRAS G12C | Inquire | |
| 4197 | Golgicide A | Potent, highly specific and reversible inhibitor of GBF1 | €95.00 | |
| 2302 | Kobe 0065 | HRAS inhibitor | €70.00 | |
| 2017 | ML 210 | Chemical probe that selectively kills cells induced to express mutant RAS | €115.00 | |
| 3761 | MRTX1133 | First-in-class, noncovalent, selective & reversible inhibitor of KRASG12D mutant | €220.00 | |
| 3733 | MRTX1257 | Irreversible covalent inhibitor of KRAS G12C | Inquire | |
| 4036 | MRTX849 | Potent, mutation-selective, and irreversible covalent inhibitor of KRAS-G12C | Inquire | |
| 3622 | NAV-2729 | Dual Arf1/Arf6 inhibitor; FATP2 inhibitor | €80.00 | |
| 2396 | RBC 8 | Inhibitor of the RAS-like small GTPases RalA and RalB | €105.00 | |
| 3558 | Vericiguat | Potent and orally available sGC stimulator | €140.00 | |