Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2434 | 1-Deazaadenosine | Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro | €140.00 | |
| 1190 | 2-Chloroadenosine | Adenosine A1 and A2A agonist | €65.00 | |
| 1188 | Adenosine amine congener | Adenosine A1 agonist | €125.00 | |
| 4069 | AZD4635 | Potent and selective adenosine A2A antagonist | Inquire | |
| 2317 | BAY 60-6583 | Potent and highly selective A2BAR (Adenosine) agonist | €125.00 | |
| 3736 | CGS 15943 | Potent and selective adenosine antagonist | €80.00 | |
| 1319 | CGS 21680 hydrochloride | Adenosine A2A agonist | €95.00 | |
| 3970 | CNDAC hydrochloride | Induces DNA damage and apoptosis. | €145.00 | |
| 3825 | Cordycepin | Nucleoside analogue; Anticancer and anti-inflammatory agent | €60.00 | |
| 3085 | CPI-444 | Potent, selective and oral adenosine A2A antagonist | €85.00 | |
| 2283 | Desmethyl SCH 442416 | Radioligand precursor of the adenosine A2A antagonist SCH 442416 | €300.00 | |
| 3847 | DPTN | Highly potent A3 receptor antagonist | €130.00 | |
| 1287 | GR 79236 | Adenosine A1 agonist | €120.00 | |
| 1423 | Istradefylline | Adenosine A2A antagonist | €75.00 | |
| 3684 | MRS 1220 | Potent and selective hA3 receptor antagonist | €140.00 | |
| 2076 | MRS 1523 | Adenosine A3 receptor antagonist | €130.00 | |
| 3826 | NUC-7738 | Prodrug of Cordycepin; Anticancer agent | €160.00 | |
| 4132 | PBF-509 | Selective Adenosine 2A receptor antagonist | Inquire | |
| 1603 | Rolofylline | Adenosine A1 antagonist | €90.00 | |
| 1852 | Rolofylline metabolite M1-cis | Adenosine A1 antagonist | €105.00 | |
| 1851 | Rolofylline metabolite M1-trans | Adenosine A1 antagonist | €105.00 | |
| 1264 | SCH 442416 | Adenosine A2A antagonist | €90.00 | |
| 1253 | SCH 58261 | Adenosine A2A antagonist | €90.00 | |
| 1265 | SDZ-WAG 994 | Adenosine A1 agonist | €125.00 | |
| 1193 | UK 432097 | Adenosine A2A agonist | €125.00 | |
| 3519 | VCP171 | Positive allosteric modulator (PAM) of A1 receptors | €120.00 | |
| 3626 | Vipadenant | Potent, selective and orally active adenosine A2A antagonist | €90.00 | |
| 4001 | ZM241385 | Potent and selective adenosine A2A antagonist | €110.00 | |