Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1077 (+)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €155.00
1078 (-)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €155.00
1076 (±)-Epibatidine dihydrochloride Nicotinic acetylcholine receptor agonist €95.00
2694 4BP-TQS Allosteric agonist of α7 nAChR €110.00
2401 AT 1001 High affinity and selective α3β4 nAChR ligand with partial agonistic and antagonistic effects €95.00
3513 Bethanechol chloride Muscarinic receptor (mAChR) agonist €50.00
2796 Clozapine N-oxide Muscarinic DREADD agonist €85.00
3478 Dehydroevodiamine hydrochloride Potent acetylcholinesterase inhibitor €70.00
1438 Donepezil hydrochloride Acetylcholinesterase inhibitor €60.00
2621 GAT107 allosteric agonist and PAM of α7 nAChR €110.00
3707 GLN-1062 Brain-pentrant prodrug of galantamine; Acetylcholinesterase inhibitor  Recently added €120.00
1289 GMC 1-109 Clozapine analog devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity €125.00
2860 GTS 21 dihydrochloride Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist €90.00
3280 JHU37152 Potent and CNS-active DREADD agonist €90.00
3281 JHU37160 Potent and CNS-active DREADD agonist €90.00
1679 MDL 201012 Muscarinic M3 antagonist €110.00
3505 Oxybutynin hydrochloride Competitive M1/M2/M3 mAChR antagonist €50.00
3286 Penehyclidine hydrochloride Anticholinergic drug €130.00
2109 PHA 543613 dihydrochloride nAChR agonist (α7 sub-unit selective) €115.00
2908 PNU 282987 hydrochloride nAChR agonist (α7 sub-unit selective) €90.00
3151 QND7 nAChR antagonist (α7 sub-unit selective) €130.00
3167 Rivastigmine tartrate Centrally selective acetylcholinesterase inhibitor €60.00
2463 TBPB Allosteric activator of the M1 acetylcholine receptor devoid of M2-M5 activity. €105.00
2049 Tolterodine L-tartrate Muscarinic receptor (mAChR) antagonist €60.00
3648 Trospium chloride Specific, orally active and competitive muscarinic receptor (mAChR) antagonist  Recently added €60.00
1384 Varenicline dihydrochloride Nicotinic acetylcholine receptor agonist €80.00
2074 Varenicline tartrate Selective α4β2 nicotinic acetylcholine receptor (nAChR) partial agonist €80.00
1988 VU 0029767 PAM of mAChR M1 that potentiates the agonistic effect of Ach €110.00
1483 VU 0152100 PAM of M4 mAChR €85.00
1786 VU 0238429 Selective PAM of M5 mAChR (CHRM5) €105.00

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