Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
2694 4BP-TQS Allosteric agonist of α7 nAChR €105.00
2401 AT 1001 High affinity and selective α3β4 nAChR ligand with partial agonistic and antagonistic effects €95.00
2796 Clozapine N-oxide Muscarinic DREADD agonist €85.00
1438 Donepezil hydrochloride Acetylcholinesterase inhibitor €75.00
1077 Epibatidine dihydrochloride, (+)- Nicotinic acetylcholine receptor agonist €155.00
1078 Epibatidine dihydrochloride, (-)- Nicotinic acetylcholine receptor agonist €155.00
1076 Epibatidine dihydrochloride, (±)- Nicotinic acetylcholine receptor agonist €95.00
2621 GAT107 allosteric agonist and PAM of α7 nAChR €105.00
1289 GMC 1-109 Clozapine analog devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity €125.00
2860 GTS 21 dihydrochloride Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist €90.00
1679 MDL 201012 Muscarinic M3 antagonist €110.00
2109 PHA 543613 dihydrochloride nAChR agonist (α7 sub-unit selective) €115.00
2908 PNU 282987 hydrochloride nAChR agonist (α7 sub-unit selective) €90.00
2463 TBPB Allosteric activator of the M1 acetylcholine receptor devoid of M2-M5 activity. €105.00
2049 Tolterodine L-tartrate Muscarinic receptor (mAChR) antagonist €90.00

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