Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1077 | (+)-Epibatidine dihydrochloride | Nicotinic acetylcholine receptor agonist | €155.00 | |
| 1078 | (-)-Epibatidine dihydrochloride | Nicotinic acetylcholine receptor agonist | €155.00 | |
| 3669 | (S)-(+)-Dimethindene maleate | Potent and selective M2 muscarinic receptor antagonist | €125.00 | |
| 1076 | (±)-Epibatidine dihydrochloride | Nicotinic acetylcholine receptor agonist | €95.00 | |
| 2694 | 4BP-TQS | Allosteric agonist of α7 nAChR | €110.00 | |
| 2401 | AT 1001 | High affinity and selective α3β4 nAChR ligand with partial agonistic and antagonistic effects | €95.00 | |
| 3513 | Bethanechol chloride | Muscarinic receptor (mAChR) agonist | €50.00 | |
| 2796 | Clozapine N-oxide | Muscarinic DREADD agonist | €95.00 | |
| 3478 | Dehydroevodiamine hydrochloride | Potent acetylcholinesterase inhibitor | €70.00 | |
| 3965 | Deschloroclozapine | Potent, selective, brain penetrable DREADD agonist | €90.00 | |
| 1438 | Donepezil hydrochloride | Acetylcholinesterase inhibitor | €60.00 | |
| 4086 | Emraclidine | Highly selective, brain-penetrant PAM of M4 mAChR | €140.00 | |
| 4113 | Encenicline hydrochloride | Selective and brain-penetrant α7 nicotinic acetylcholine receptor (nAChR) partial agonist | Recently added | €120.00 |
| 2621 | GAT107 | allosteric agonist and PAM of α7 nAChR | €110.00 | |
| 3707 | GLN-1062 | Brain-pentrant prodrug of galantamine; Acetylcholinesterase inhibitor | €120.00 | |
| 1289 | GMC 1-109 | Clozapine analog devoid of DA, 5-HT2, H1 and α1 affinities, but with high M1 affinity | €125.00 | |
| 2860 | GTS 21 dihydrochloride | Selective α7 nicotinic acetylcholine receptor (nAChR) partial agonist | €90.00 | |
| 3280 | JHU37152 | Potent and CNS-active DREADD agonist | €90.00 | |
| 3281 | JHU37160 | Potent and CNS-active DREADD agonist | €90.00 | |
| 1679 | MDL 201012 | Muscarinic M3 antagonist | €110.00 | |
| 3658 | Neostigmine methyl sulfate | Reversible acetylcholinesterase inhibitor | €40.00 | |
| 3505 | Oxybutynin hydrochloride | Competitive M1/M2/M3 mAChR antagonist | €50.00 | |
| 3286 | Penehyclidine hydrochloride | Anticholinergic drug | €130.00 | |
| 2109 | PHA 543613 dihydrochloride | nAChR agonist (α7 sub-unit selective) | €120.00 | |
| 2908 | PNU 282987 hydrochloride | nAChR agonist (α7 sub-unit selective) | €90.00 | |
| 3151 | QND7 | nAChR antagonist (α7 sub-unit selective) | €130.00 | |
| 3167 | Rivastigmine tartrate | Centrally selective acetylcholinesterase inhibitor | €60.00 | |
| 2463 | TBPB | Allosteric activator of the M1 acetylcholine receptor devoid of M2-M5 activity. | €105.00 | |
| 2049 | Tolterodine L-tartrate | Muscarinic receptor (mAChR) antagonist | €60.00 | |
| 3648 | Trospium chloride | Specific, orally active and competitive muscarinic receptor (mAChR) antagonist | €60.00 | |