Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

26 Item(s)

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Axon ID Name Description From price
1810 Bortezomib Inhibitor of 26S proteasome €80.00
2935 COH000 First-in-class, highly specific, covalent allosteric inhibitor of SUMO E1 €175.00
1798 Eeyarestatin I Inhibitor of endoplasmic reticulum associated protein degradation (ERAD) €80.00
3426 IU1-47 Potent and selective inhibitor deubiquitinase USP14 €80.00
2449 LDN 57444 Reversible, competitive inhibitor of UCH-L1 deubiquitinase €95.00
3724 M-3258 Selective inhibitor of LMP7 subunit of the immunoproteasome  Recently added Inquire
1869 MG 132 Inhibitor of 26S proteasome €80.00
2309 ML 323 Selective, reversible and potent inhibitor of the USP1–UAF1 deubiquitinase complex €95.00
2995 ML 367 Inhibitor of ATAD5 stabilization €125.00
3109 ML-792 Potent and selective inhibitor of SUMO-activating enzyme (SAE) €145.00
2678 ML364 Inhibitor of the deubiquitinase USP2 €125.00
2556 MLN 2238 Selective and reversible 20S proteasome inhibitor €85.00
2557 MLN 9708 Citrate prodrug of MLN 2238, selective and reversible 20S proteasome inhibitor €95.00
2565 N106 Activator of E1 ligase mediated SERCA2a SUMOylation €95.00
2228 NSC 687852 Inhibitor of 19S regulatory-particle–associated deubiquitinases (DUBs: UCHL5 and USP14) €90.00
2199 ONX 0914 Selective inhibitor of LMP7 subunit of the immunoproteasome. €70.00
2011 P 005091 Inhibitor of deubiquitinase USP7 and USP47 €95.00
1906 P 22077 Inhibitor of deubiquitinase USP7 and USP47 €95.00
1953 PRT 4165 E3 Ubiquitin ligase Bmi1/Ring1A inhibitor €70.00
1904 SMER 3 Inhibitor of an SCF family E3 Ubiquitin ligase €90.00
2512 Spautin 1 Inhibitor of USP10 and USP13 and Beclin1 related autophagy €95.00
3608 STD1T Inhibitor of the deubiquitinase USP2a €160.00
2333 TCID Potent inhibitor of UCHL3 with >100-fold selectivity over UCHL1 €80.00
2991 USP7-USP47 inhibitor Selective inhibitor of deubiquitinase USP7 and USP47 €90.00
1779 WP 1130 Deubiquitinase Inhibitor €95.00
2984 WS-383 Highly potent, selective, and cellular active inhibitor of DCN1-UBC12 protein-protein interaction €125.00

26 Item(s)

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