Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1892 | 1-NM-PP1 | Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) | €95.00 | |
| 2496 | 2,5-Dimethylcelecoxib | Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity | €75.00 | |
| 2417 | 6-Chloropurine riboside | Building block in the synthesis of 6-substituted purine ribosides | €75.00 | |
| 3957 | A-1155463 dihydrochloride | BH3 mimetic Ligand of BCL protein BCL-XL | Inquire | |
| 4008 | A-1210477 | Potent and selective inhibitor of MCL-1 | Inquire | |
| 3972 | A-1331852 | BH3 mimetic Ligand of BCL protein BCL-XL | €120.00 | |
| 3564 | ABCA1 inducer compound G | ABCA1 inducer targeting OSBPL7 | €150.00 | |
| 1873 | Abiraterone | Inhibitor of CYP17A1 | €90.00 | |
| 1874 | Abiraterone acetate | Prodrug of Abiraterone; Inhibitor of CYP17A1 | €90.00 | |
| 2141 | ABT 199 | Potent, orally bioavailable BCL-2-selective inhibitor | €70.00 | |
| 3821 | ABT-263 | Potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins | Inquire | |
| 1884 | Alectinib | Orally available and selective ALK inhibitor | €70.00 | |
| 3686 | AMG-176 | Potent and selective Mcl-1 inhibitor | €490.00 | |
| 3303 | Artemether | Antimalarial drug | €50.00 | |
| 3886 | Artesunate | Antimalarial drug | €50.00 | |
| 3527 | Atovaquone | Broad-spectrum antiprotozoal drug | €95.00 | |
| 2099 | Avridine | Lipoidal amine; interferon-inducing and adjuvant properties | €80.00 | |
| 1170 | Axon 1170 | Building Block; unknown pharmacology | €380.00 | |
| 1171 | Axon 1171 | Building Block; unknown pharmacology | €180.00 | |
| 1456 | AZD0530 difumarate | Inhibitor of SRC and ABL tyrosine kinases | €70.00 | |
| 2153 | AZD3463 | Potent inhibitor of ALK and IGF1R | €105.00 | |
| 3814 | AZD4320 | BH3-mimetic inhibitor of BCL-2 protein | Inquire | |
| 3731 | AZD5991 | BH3-Groove binding Mcl-1 inhibitor | Inquire | |
| 2185 | BAM 7 | Selective small-molecule activator of proapoptotic BAX | €90.00 | |
| 3714 | BCL-201 dihydrochloride | BH3-mimetic inhibitor of BCL-2 protein | Inquire | |
| 2624 | BF844 | CLRN1-N48K stabilizer | €105.00 | |
| 1828 | BH3I 1 | Inhibitor of Bcl-2 family protein | €125.00 | |
| 3047 | BI-6C9 | Inhibitor of BID protein | €145.00 | |
| 3295 | BIA | TMBIM6 antagonist | €120.00 | |
| 2978 | Brigatinib | Potent, selective, and orally active anaplastic lymphoma kinase (ALK) inhibitor | €80.00 | |