Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
2496 2,5-Dimethylcelecoxib Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity €75.00
2417 6-Chloropurine riboside Building block in the synthesis of 6-substituted purine ribosides €75.00
3564 ABCA1 inducer compound G ABCA1 inducer targeting OSBPL7 €150.00
1873 Abiraterone Inhibitor of CYP17A1 €90.00
1874 Abiraterone acetate Prodrug of Abiraterone; Inhibitor of CYP17A1 €90.00
2141 ABT 199 Potent, orally bioavailable BCL-2-selective inhibitor €70.00
3821 ABT-263 Potent, selective and orally bioavailable inhibitor of B-cell lymphoma-2 (BCL-2) family proteins  Recently added Inquire
1884 Alectinib Orally available and selective ALK inhibitor €80.00
3686 AMG-176 Potent and selective Mcl-1 inhibitor Inquire
3303 Artemether Antimalarial drug €50.00
3527 Atovaquone Broad-spectrum antiprotozoal drug €95.00
2099 Avridine Lipoidal amine; interferon-inducing and adjuvant properties €80.00
1170 Axon 1170 Building Block; unknown pharmacology €330.00
1171 Axon 1171 Building Block; unknown pharmacology €180.00
1456 AZD0530 difumarate Inhibitor of SRC and ABL tyrosine kinases €70.00
2153 AZD3463 Potent inhibitor of ALK and IGF1R €105.00
3814 AZD4320 BH3-mimetic inhibitor of BCL-2 protein  Recently added Inquire
3731 AZD5991 BH3-Groove binding Mcl-1 inhibitor Inquire
2185 BAM 7 Selective small-molecule activator of proapoptotic BAX €90.00
3714 BCL-201 dihydrochloride BH3-mimetic inhibitor of BCL-2 protein Inquire
2624 BF844 CLRN1-N48K stabilizer €105.00
1828 BH3I 1 Inhibitor of Bcl-2 family protein €125.00
3047 BI-6C9 Inhibitor of BID protein €145.00
3295 BIA TMBIM6 antagonist €120.00
2978 Brigatinib Potent, selective, and orally active anaplastic lymphoma kinase (ALK) inhibitor €80.00
2804 Broxaldine Antiprotozoal drug €65.00
3431 BTSA1 Potent activator of proapoptotic BAX €110.00
3481 BTYNB isomer Ring-closed isomer of BTYNB €110.00
3156 Centhaquin Centrally acting hypotensive agent €90.00

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