Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1909 A 1070722 Selective inhibitor of GSK-3 €95.00
1698 A 770041 Orally active src-family selective lck inhibitor €140.00
2971 Amcasertib First-in-class stemness kinase inhibitor €145.00
1857 AP 24534 BCR-ABL kinase inhibitor (including T315I mutation) €70.00
2167 AR-A 014418 ATP-competitive GSK-3 inhibitor €85.00
3041 ARN 3236 Potent, selective, ATP-competitive, and orally available inhibitor of SIK2 €80.00
2187 AS 1892802 Potent, selective, ATP-competitive ROCK inhibitor €95.00
2005 ASP 3026 Inhibitor of the oncogenic fusion kinase EML4-ALK €80.00
2166 AT 13148 dihydrochloride ATP-competitive inhibitor of multi-AGC kinases €70.00
5051 Axon Ligands™ Cell signaling and Oncology compound library Axon Ligands™ Cell signaling and Oncology compound library Inquire
5053 Axon Ligands™ Stem cell compound library Axon Ligands™ Stem cell compound library Inquire
2669 AZ13705339 Potent and selective PAK1 inhibitor €125.00
2171 AZD1080 Selective inhibitor of GSK-3α and GSK-3β €90.00
2795 AZD1208 Pim kinase inhibitor €70.00
2194 AZD2858 hydrochloride Potent and highly selective Glycogen Synthase Kinase-3β inhibitor €95.00
2981 B106 Potent and selective PKC-δ inhibitor €135.00
3832 BAY-1816032 Potent and selective BUB1 (Mitotic checkpoint serine/threonine-protein kinase) inhibitor Inquire
1544 BIBW 2992 EGFR and ErbB-2/HER2 tyrosine kinase inhibitor €50.00
1693 BIO GSK-3 inhibitor €90.00
2798 BPKDi PKD inhibitor €155.00
2931 BRD0705 First-in-class, paralog selective GSK3α inhibitor €210.00
3153 BRD5648 Negative control compound of BRD0705 as a GSK3α inhibitor €180.00
2753 CCG 232601 Rho/MRTF/SRF transcriptional pathway inhibitor €160.00
3092 CCG-203971 Rho/MRTF/SRF transcriptional pathway inhibitor €60.00
3069 CCG-222740 Potent and selective Rho/MRTF/SRF transcriptional pathway inhibitor €145.00
1126 CHIR98014 GSK-3 inhibitor €99.00
1386 CHIR99021 GSK-3 inhibitor €60.00
2435 CHIR99021 dihydrochloride GSK-3 inhibitor €60.00
1976 CID 2011756 ATP-competitive and cell-permeable PKD inhibitor €125.00
1627 CID 755673 PKD inhibitor €125.00

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