Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

27 Item(s)

per page
Axon ID Name Description From price
2467 (+)-ITD-1 Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis €165.00
1744 A 77-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €80.00
1421 A 83-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €70.00
4168 BMS-986260 Potent, selective and orally bioavailable TGF-βR 1 inhibitor  Recently added €120.00
3914 CDD-1653 First-in-class, highly potent, and selective BMPR2 kinase inhibitor €110.00
1708 Dorsomorphin Inhibitor of BMP signaling. Inhibits ALK2, 3 and 6 €65.00
2150 Dorsomorphin dihydrochloride Inhibitor of BMP signaling. Inhibits ALK2, 3 and 6 €65.00
1832 GW 788388 TGF-βR 1 inhibitor €50.00
2236 IN 1130 TGF-βR 1 inhibitor €95.00
2323 ITD 1 Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis €105.00
2189 K 02288 Inhibitor of BMP signaling. Inhibits ALK1, 2, and 6 €90.00
1509 LDN 193189 hydrochloride Highly potent small molecule inhibitor of BMP type I receptors ALK2, ALK3, and ALK6 €65.00
3552 LDN 212854 Potent ALK2-biased BMP type I receptor kinase inhibitor €110.00
2201 LDN 212854 trihydrochloride Potent ALK2-biased BMP type I receptor kinase inhibitor €110.00
1491 LY 2157299 TGF-βR2 inhibitor €60.00
3892 LY-3200882 TGF-βR 1 inhibitor Inquire
3404 LY-364947 Potent, selective and ATP-competitive TGF-βR 1 inhibitor €90.00
1661 SB 431542 TGF-βR1 inhibitor; ALK inhibitor €70.00
2197 SB 505124 Selective inhibitor of TGF-β type I receptors ALK4 and ALK5 €95.00
2285 SB 525334 Potent and selective inhibitor of the TGF-βR1 (ALK5) receptor €105.00
4165 SB4 Potent BMP agonist  Recently added €80.00
1387 SD 208 TGF-βR 1 inhibitor €50.00
2903 SJ000291942 Activator of the canonical BMP signaling pathway €95.00
2943 SRI-011381 hydrochloride TGF-β signaling agonist €125.00
5004 Stem Cell LSB inhibitor Set Set of BMP inhibitor LDN 193189 (Axon 1509) and TGF-β inhibitor SB 431542 (Axon 1661) €90.00
5005 Stem Cell LSC inhibitor Set Set of LDN 193189 HCl, SB 431542 and CHIR99021, inhibitors of BMP, TGF-β, and GSK-3 resp. €130.00
3076 TJ191 Potent and selective anti-cancer agent targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells €120.00

27 Item(s)

per page
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