Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2062 | Alprostadil | Prostaglandin EP (1-4) receptor antagonist | €125.00 | |
| 2145 | AZD1981 | Selective CRTH2 (aka DP2) antagonist | €90.00 | |
| 3073 | BAY 1316957 | Highly potent, specific, and selective PGE2 receptor hEP4 antagonist | €150.00 | |
| 3904 | BAY-0069 | Potent covalent PPARγ inverse agonist | €90.00 | |
| 3809 | BAY-4931 | Potent covalent PPARγ inverse agonist | €120.00 | |
| 1950 | CDDO | A potent multifunctional anti-tumor agent. PPAR-γ agonist | €80.00 | |
| 2788 | ER-819762 | Highly selective, and orally available PGE2 receptor EP4 antagonist | €155.00 | |
| 3787 | Grapiprant | Potent, selective, competitive and orally bioavailable prostaglandin EP4 receptor antagonist | €100.00 | |
| 2533 | Hydroxypioglitazone | Active metabolite of Pioglitazone (M-IV), a PPARγ agonist | €180.00 | |
| 1480 | MK 0524 sodium salt | PGD2 receptor DP1 antagonist | €130.00 | |
| 1512 | ONO 8711 dicyclohexyl amine salt | PGE1 receptor EP1 antagonist | €120.00 | |
| 2024 | PF 04418948 | Prostaglandin EP2 receptor antagonist | €95.00 | |
| 2020 | PF 4693627 | Selective and orally bioavailable inhibitor of mPGES-1 | €130.00 | |
| 3255 | Pioglitazone hydrochloride | PPARγ agonist; antidiabetic drug | €50.00 | |
| 2874 | Ralinepag | Potent, orally active IP receptor (PGI2) agonist | €150.00 | |
| 2443 | Rosiglitazone | PPARγ agonist; antidiabetic drug and stem cell differentiator | €95.00 | |
| 1605 | S 5751 | PGD2 receptor DP1 antagonist | €115.00 | |
| 2605 | Selexipag | Prodrug of MRE 269, a potent IP receptor (PGI2) agonist | €90.00 | |
| 3212 | TG11-77 hydrochloride | Potent, selective, water soluble, brain-permeable EP2 receptor antagonist | €130.00 | |
| 1913 | Timapiprant | Selective DP2 (CRTH2) antagonist | €90.00 | |
| 3966 | TM30089 sodium | Selective CRTH2 antagonist | Inquire | |