Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1309 | (R)-(-)-BMS 204352 | Potassium channel opener; Less active enantiomer of Axon 1112 | €145.00 | |
| 1308 | (±)-BMS 204352 | Potassium channel opener; racemate of Axon 1112 | Inquire | |
| 1313 | 1-EBIO | K+ channel opener (Ca2+ activated) | €50.00 | |
| 3019 | A2764 dihydrochloride | Selective inhibitor of the TRESK potassium channel | €105.00 | |
| 3060 | A2793 | Inhibitor of the TRESK and TASK-1 potassium channel | €95.00 | |
| 2979 | ASP 2905 | Potent, selective and orally active KCNH3 (Kv12.2) inhibitor | €125.00 | |
| 2243 | AVE 0118 hydrochloride | Potassium channel blocker (Kv1.5 (IKur), Kv4.3 (Ito), Kir3.4 (IKAch), and IKr currents) | €120.00 | |
| 1112 | BMS 204352 | Maxi K+ channel opener | €120.00 | |
| 4122 | C101248 | First potent and selective THIK-1 inhibitor | €120.00 | |
| 1294 | Chromanol 293B | KCNQ1 channel blocker | €120.00 | |
| 1322 | DMP 543 | K+ channel blocker; Ach release stimulator | €90.00 | |
| 2103 | Dofetilide | Kv11.1 (hERG) channel blocker | €85.00 | |
| 4173 | Ebio1 | Potent and highly selective KCNQ2 activator | €130.00 | |
| 1437 | Flupirtine maleate | Analgesic | €65.00 | |
| 2064 | Glibenclamide potassium salt | KATP channel blocker; inhibits SUR1 | €50.00 | |
| 3503 | Glipizide | KATP channel blocker; inhibits SUR1 | €50.00 | |
| 1757 | HMR 1098 | K+ channel blocker (SUR1/Kir6.2 selective) | €95.00 | |
| 2724 | ICA-069673 | KCNQ2/KCNQ3 channel opener; Anti-convulsant | €90.00 | |
| 3091 | ICA-110381 | KCNQ2/KCNQ3 channel opener; Anti-convulsant | €80.00 | |
| 3495 | Ivabradine hydrochloride | Selective sinus node I(f) channel inhibitor | €50.00 | |
| 1734 | K+ Channel inhibitor 1734 | Building Block for synthesis of Kv1.5 (IKur) inhibitors | €65.00 | |
| 3516 | KCa modulator RA-2 | Potent and selective KCa2/3 pan inhibitor | €110.00 | |
| 1735 | Kv1.3 Channel blocker 42 | Kv1.3 potassium channel blocker | €110.00 | |
| 4046 | Levosimendan | Calcium sensitiser | €60.00 | |
| 3032 | LUF7244 | Potent negative allosteric modulator (NAM) of the Kv11.1 (hERG) channel | €140.00 | |
| 3490 | Minoxidil | K+ channel opener (ATP sensitive, vascular) | €50.00 | |
| 2747 | ML 213 | KCNQ2/KCNQ4 channel opener | €75.00 | |
| 2436 | ML 297 | First potent and selective activator of the GIRK potassium channel | €95.00 | |
| 2872 | ML 335 | Selective activator of the TREK-1 and TREK-2 potassium channel | €110.00 | |
| 2840 | ML 365 | Potent and selective inhibitor of the TASK-1 potassium channel | €135.00 | |