Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1309 (R)-(-)-BMS 204352 Potassium channel opener; Less active enantiomer of Axon 1112 €145.00
1308 (±)-BMS 204352 Potassium channel opener; racemate of Axon 1112 Inquire
1313 1-EBIO K+ channel opener (Ca2+ activated) €50.00
3019 A2764 dihydrochloride Selective inhibitor of the TRESK potassium channel €105.00
3060 A2793 Inhibitor of the TRESK and TASK-1 potassium channel €95.00
2979 ASP 2905 Potent, selective and orally active KCNH3 (Kv12.2) inhibitor €125.00
2243 AVE 0118 hydrochloride Potassium channel blocker (Kv1.5 (IKur), Kv4.3 (Ito), Kir3.4 (IKAch), and IKr currents) €120.00
1112 BMS 204352 Maxi K+ channel opener €110.00
1294 Chromanol 293B KCNQ1 channel blocker €95.00
1322 DMP 543 K+ channel blocker; Ach release stimulator €90.00
2103 Dofetilide Kv11.1 (hERG) channel blocker €85.00
1437 Flupirtine maleate Analgesic €65.00
2064 Glibenclamide potassium salt KATP channel blocker; inhibits SUR1 €50.00
3503 Glipizide KATP channel blocker; inhibits SUR1 €50.00
1757 HMR 1098 K+ channel blocker (SUR1/Kir6.2 selective) €95.00
2724 ICA-069673 KCNQ2/KCNQ3 channel opener; Anti-convulsant €90.00
3091 ICA-110381 KCNQ2/KCNQ3 channel opener; Anti-convulsant €80.00
3495 Ivabradine hydrochloride Selective sinus node I(f) channel inhibitor €50.00
1734 K+ Channel inhibitor 1734 Building Block for synthesis of Kv1.5 (IKur) inhibitors €65.00
3516 KCa modulator RA-2 Potent and selective KCa2/3 pan inhibitor €110.00
1735 Kv1.3 Channel blocker 42 Kv1.3 potassium channel blocker €110.00
3032 LUF7244 Potent negative allosteric modulator (NAM) of the Kv11.1 (hERG) channel €140.00
3490 Minoxidil K+ channel opener (ATP sensitive, vascular) €50.00
2747 ML 213 KCNQ2/KCNQ4 channel opener €75.00
2436 ML 297 First potent and selective activator of the GIRK potassium channel €95.00
2872 ML 335 Selective activator of the TREK-1 and TREK-2 potassium channel €115.00
2840 ML 365 Potent and selective inhibitor of the TASK-1 potassium channel €135.00
2615 ML252 Selective and brain penetrant KCNQ2 inhibitor €95.00
3196 ML277 Potent and selective KCNQ1 channel activator €80.00
3641 Nateglinide KATP channel blocker; inhibits SUR1 €60.00

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