Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2639 | AMG 232 | Potent, selective, and orally bioavailable MDM2-p53 inhibitor | €120.00 | |
| 3765 | DS-3032 | Orally available, potent and selective inhibitor of the p53-MDM2 interaction | Inquire | |
| 1643 | HLI 373 | HDM2 inhibitor | €100.00 | |
| 1538 | JNJ 26854165 | HDM2 inhibitor | €105.00 | |
| 1586 | JNJ 26854165 dihydrochloride | HDM2 inhibitor | €105.00 | |
| 1585 | Nutlin-3 | MDM2 inhibitor (p53 specific) | €95.00 | |
| 1880 | Nutlin-3a | Inhibitor of MDM2 | €95.00 | |
| 1881 | Nutlin-3b | Less potent (+)-enantiomer of Nutlin-3 | €90.00 | |
| 3751 | NVP-CGM097 | Inhibitor of MDM2 | Inquire | |
| 3752 | NVP-CGM097 dihydrochloride | Inhibitor of MDM2 | Inquire | |
| 4035 | RG-7388 | Potent and selective MDM2 antagonist | Inquire | |
| 2009 | RITA | Activates p53 through inhibition of MDM2 | €105.00 | |
| 2741 | SAR405838 | MDM2-p53 inhibitor | €125.00 | |
| 3737 | Siremadlin | Potent, selective, and orally bioavailable MDM2-p53 inhibitor | €130.00 | |
| 2164 | SJ 172550 | Small molecule inhibitor of MDMX | €95.00 | |
| 2437 | SP 141 | Specific MDM2 inhibitor with therapeutic effects in breast cancer models | €120.00 | |
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