Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2089 | 7,8-Dihydroxyflavone | Tyrosine kinase receptor B (TrkB) agonist | €55.00 | |
| 2468 | ANA 12 | Selective TrkB antagonist with anxiolytic and antidepressant activity in mice | €90.00 | |
| 1610 | AZ 23 | TrkA and TrkB inhibitor | €80.00 | |
| 2248 | GNF 5837 | Potent, selective, and orally bioavailable tropomyosin receptor kinase (Trk) inhibitor | €90.00 | |
| 1251 | GW 441756 | TrkA inhibitor | €75.00 | |
| 3407 | LOXO-101 sulfate | First-in-class, potent, highly selective and ATP-competitive TRK inhibitor | €80.00 | |
| 3901 | LOXO-195 | Trk inhibitor | Inquire | |
| 2174 | PD90780 | Inhibitor of NGFs binding to the P75 NGFR | €110.00 | |
| 3775 | TrkB agonist prodrug R13 | Prodrug of 7,8-Dihydroxyflavone; TrkB agonist | €120.00 | |
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