Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
Axon ID | Name | Description | From price | |
---|---|---|---|---|
2786 | (±)-PH 797804 | Inhibitor of p38α MAPK | €115.00 | |
1291 | AEG 3482 | JNK inhibitor | €90.00 | |
3682 | AMZ30 | Potent, selective and covalent PME-1 inhibitor | €130.00 | |
4217 | AS-703026 | Potent, selective and orally bioavailable small molecular inhibitor of MEK1/2 | Inquire | |
2179 | ASK1 Inhibitor 10 | Potent, selective, and orally bioavailable ASK1 inhibitor | €130.00 | |
1516 | AZD6244 | MEK1 and MEK2 inhibitor | €60.00 | |
1999 | AZD8330 | MEK 1 inhibitor | €105.00 | |
2002 | Bentamapimod | JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 | €70.00 | |
3697 | Binimetinib | Potent, selective, non-ATP-competitive and orally available allosteric inhibitor of MEK1/2 | €60.00 | |
1358 | BIRB 796 | MAPK inhibitor (p38 specific) | €65.00 | |
1809 | BIX 02189 | MEK5 inhibitor; ERK5 inhibitor | €110.00 | |
3346 | BIX02188 | Potent MEK5 inhibitor | €110.00 | |
1808 | BIX02188-Me | MEK5 inhibitor; ERK5 inhibitor | €110.00 | |
2856 | BMS 582949 | Inhibitor of p38α MAPK | €155.00 | |
2025 | CC-401 | ATP-competitive JNK inhibitor | €120.00 | |
2634 | CC-930 | Potent, selective, and orally active anti-fibrotic JNK inhibitor | €95.00 | |
1694 | FR 180204 | ERK inhibitor; AP-1 inhibitor | €95.00 | |
4148 | GDC-0973 | Orally bioavailable, potent and selective small-molecule inhibitor of mitogen-activated protein kinase 1 | Inquire | |
3741 | GDC-0994 | ERK1/2 inhibitor | Inquire | |
3625 | GNE-3511 | Potent, selective, orally bioavailable and brain-penetrant DLK inhibitor | €90.00 | |
1761 | GSK 1120212 | MEK1 and MEK2 inhibitor | €70.00 | |
3895 | GSK329 | Highly potent and selective TNNI3K inhibitor | €130.00 | |
3059 | GW 284543 hydrochloride | Selective MEK5 inhibitor | €95.00 | |
4195 | HRX215 | First-in-class, potent, selective and orally active MKK4 inhibitor | Recently added | €180.00 |
2949 | JNK inhibitor VIII | Selective, ATP-competitive, and cell-permeable JNK inhibitor | €105.00 | |
2361 | JNK-IN-8 | Remarkably potent and selective covalent inhibitor of JNK | €95.00 | |
1895 | LY 2228820 | Inhibitor of p38 MAPK | €105.00 | |
3893 | LY-3214996 | Orally bioavailable, potent and highly selective inhibitor of ERK1 and ERK2 | Inquire | |
3197 | Mitochonic acid 5 | Mitochondrial drug; Activator of MAPK-ERK-yap signalling | €90.00 | |
3440 | MK2 inhibitor III | Potent and selective MK-2 inhibitor | €120.00 |