Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
1291 AEG 3482 JNK inhibitor €85.00
2179 ASK1 Inhibitor 10 Potent, selective, and orally bioavailable ASK1 inhibitor €125.00
1516 AZD 6244 MEK1 and MEK2 inhibitor €60.00
1999 AZD 8330 MEK 1 inhibitor €105.00
2002 Bentamapimod JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 €70.00
3697 Binimetinib Potent, selective, non-ATP-competitive and orally available allosteric inhibitor of MEK1/2  Recently added €60.00
1358 BIRB 796 MAPK inhibitor (p38 specific) €65.00
1809 BIX 02189 MEK5 inhibitor; ERK5 inhibitor €110.00
3346 BIX02188 Potent MEK5 inhibitor €110.00
1808 BIX02188-Me MEK5 inhibitor; ERK5 inhibitor €110.00
2856 BMS 582949 Inhibitor of p38α MAPK €155.00
2025 CC-401 ATP-competitive JNK inhibitor €115.00
2634 CC-930 Potent, selective, and orally active anti-fibrotic JNK inhibitor €95.00
1694 FR 180204 ERK inhibitor; AP-1 inhibitor €95.00
3741 GDC-0994 ERK1/2 inhibitor  Recently added Inquire
3625 GNE-3511 Potent, selective, orally bioavailable and brain-penetrant DLK inhibitor €90.00
1761 GSK 1120212 MEK1 and MEK2 inhibitor €70.00
3059 GW 284543 hydrochloride Selective MEK5 inhibitor €95.00
2949 JNK inhibitor VIII Selective, ATP-competitive, and cell-permeable JNK inhibitor €105.00
2361 JNK-IN-8 Remarkably potent and selective covalent inhibitor of JNK €95.00
1895 LY 2228820 Inhibitor of p38 MAPK €105.00
3197 Mitochonic acid 5 Mitochondrial drug; Activator of MAPK-ERK-yap signalling €90.00
3440 MK2 inhibitor III Potent and selective MK-2 inhibitor €120.00
2366 NG 25 trihydrochloride Type II inhibitor of TAK1 (MAP3K7) and MAP4K2 (GCK) €75.00
1814 NQDI 1 Inhibitor of apoptosis signal-regulating kinase 1 (ASK1) €115.00
1408 PD 0325901 MEK1 and MEK2 inhibitor €50.00
1365 PD 169316 MAPK inhibitor (p38 specific) €95.00
1368 PD 184352 MEK 1 inhibitor €80.00
1223 PD 98059 MEK inhibitor €80.00

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