Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

Items 1 to 30 of 63 total

per page
Page:
  1. 1
  2. 2
  3. 3
Axon ID Name Description From price
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
1291 AEG 3482 JNK inhibitor €90.00
3682 AMZ30 Potent, selective and covalent PME-1 inhibitor €130.00
4217 AS-703026 Potent, selective and orally bioavailable small molecular inhibitor of MEK1/2 Inquire
2179 ASK1 Inhibitor 10 Potent, selective, and orally bioavailable ASK1 inhibitor €130.00
1516 AZD6244 MEK1 and MEK2 inhibitor €60.00
1999 AZD8330 MEK 1 inhibitor €105.00
2002 Bentamapimod JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 €70.00
3697 Binimetinib Potent, selective, non-ATP-competitive and orally available allosteric inhibitor of MEK1/2 €60.00
1358 BIRB 796 MAPK inhibitor (p38 specific) €65.00
1809 BIX 02189 MEK5 inhibitor; ERK5 inhibitor €110.00
3346 BIX02188 Potent MEK5 inhibitor €110.00
1808 BIX02188-Me MEK5 inhibitor; ERK5 inhibitor €110.00
2856 BMS 582949 Inhibitor of p38α MAPK €155.00
2025 CC-401 ATP-competitive JNK inhibitor €120.00
2634 CC-930 Potent, selective, and orally active anti-fibrotic JNK inhibitor €95.00
1694 FR 180204 ERK inhibitor; AP-1 inhibitor €95.00
4148 GDC-0973 Orally bioavailable, potent and selective small-molecule inhibitor of mitogen-activated protein kinase 1 Inquire
3741 GDC-0994 ERK1/2 inhibitor Inquire
3625 GNE-3511 Potent, selective, orally bioavailable and brain-penetrant DLK inhibitor €90.00
1761 GSK 1120212 MEK1 and MEK2 inhibitor €70.00
3895 GSK329 Highly potent and selective TNNI3K inhibitor €130.00
3059 GW 284543 hydrochloride Selective MEK5 inhibitor €95.00
4195 HRX215 First-in-class, potent, selective and orally active MKK4 inhibitor  Recently added €180.00
2949 JNK inhibitor VIII Selective, ATP-competitive, and cell-permeable JNK inhibitor €105.00
2361 JNK-IN-8 Remarkably potent and selective covalent inhibitor of JNK €95.00
1895 LY 2228820 Inhibitor of p38 MAPK €105.00
3893 LY-3214996 Orally bioavailable, potent and highly selective inhibitor of ERK1 and ERK2 Inquire
3197 Mitochonic acid 5 Mitochondrial drug; Activator of MAPK-ERK-yap signalling €90.00
3440 MK2 inhibitor III Potent and selective MK-2 inhibitor €120.00

Items 1 to 30 of 63 total

per page
Page:
  1. 1
  2. 2
  3. 3
Please wait...