Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1378 | AG 490 | JAK2 inhibitor | €65.00 | |
| 1778 | AZ 960 | JAK2 inhibitor | €95.00 | |
| 3855 | AZD-4205 | Selective and ATP-competitive inhibitor of JAK1 | Inquire | |
| 1955 | Baricitinib | Inhibitor of JAK1 and JAK2 | €70.00 | |
| 3813 | BMS-911543 | Potent, selective and orally active inhibitor of JAK2 | Inquire | |
| 3671 | CEP-33779 | Potent, selective and orally bioavailable JAK2 inhibitor | €95.00 | |
| 1338 | CP 690550 | JAK3 inhibitor | €60.00 | |
| 3861 | Decernotinib | Potent and selective,orally bioavailable Janus kinase 3 (JAK3) inhibitor | Inquire | |
| 4006 | GLPG-0634 | The first orally-available, selective inhibitor of JAK1 | Inquire | |
| 1843 | JAK2 inhibitor 13 | JAK2 inhibitor | €110.00 | |
| 2554 | LY 2784544 | Potent, selective and ATP-competitive inhibitor of mutated janus kinase 2 (JAK2V617F) | €95.00 | |
| 1681 | Momelotinib | JAK1 and JAK2 inhibitor | €80.00 | |
| 4124 | Momelotinib hydrochloride | JAK1 and JAK2 inhibitor | €120.00 | |
| 2792 | NVP-BSK805 | Potent, selective and orally bioavailable JAK2 inhibitor | €125.00 | |
| 3950 | Peficitinib | Potent and orally bioavailable JAK inhibitor | €120.00 | |
| 2217 | PF 956980 | JAK3 inhibitor; analogue of Axon 1338 and 2072 | €90.00 | |
| 1598 | Ruxolitinib | JAK1 and JAK2 inhibitor | €65.00 | |
| 2539 | Solcitinib | Selective JAK1 inhibitor for treatment of degenerative and inflammatory diseases | €90.00 | |
| 1588 | TG 101348 | JAK2 inhibitor | €80.00 | |
| 2072 | Tofacitinib citrate | Potent Janus Kinase 3 (JAK3) inhibitor | €115.00 | |
| 2316 | WP 1066 | Potent JAK2 and STAT3 inhibitor and downregulator of antiapoptotic proteins | €95.00 | |
| 2231 | XL 019 | JAK2 inhibitor | €100.00 | |